helicobacter

Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.5 kDa and the accession number is P14916.

Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreB Protein, Helicobacter pylori, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.7 kDa and the accession number is P69996.

Provides the (R)-glutamate required for cell wall biosynthesis. Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.9 kDa and the accession number is B5Z6S2.

HopQ Protein, Helicobacter pylori Hp M6, Recombinant (His & Myc) is expressed in E. coli.

HP-0175 Protein, Helicobacter pylori, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 58.8 kDa and the accession number is P56112.

Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions. vacA Protein, Helicobacter pylori, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.7 kDa and the accession number is Q48253.

Iron-storage protein.

Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases.

Iron-storage protein.

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach.