indoleamine 2,3-dioxygenase (ido)

(2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride is a cyclic amine that is structurally related to amphetamine and has been shown to have significant effects on the central nervous system.

2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.

sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate is an organosulfur compound. It has been used as a model compound to study the effects of sulfur-containing compounds on enzymatic activities and metabolic pathways. It has also been used to study the effects of sulfur-containing compounds on the regulation of bacterial growth and gene expression.

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.

2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2722 and the CAS number is 1167483-18-2. 2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one can be used as a reference standard.

(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].

2-Methyl-6-(p-tolyl)heptane-2,3-diol is a natural product for research related to life sciences. The catalog number is TN2778 and the CAS number is 117421-22-4.

The compound 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy has been isolated from the stem of Angelica dahurica, marking its first discovery from a plant source [1].

2-(4-Chlorophenyl)naphtho[2,3-d]oxazole-4,9-dione is a Heterocyclic Compound and can be used in anticancer and antimicrobial studies.

2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide is a natural product for research related to life sciences. The catalog number is TN2692 and the CAS number is 137809-97-3.

N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template.

IDO/Tubulin-IN-2 (HT2) is a powerful inhibitor of both TDO and tubulin. This compound demonstrates significant efficacy against various cancer cell lines, including U87, HepG2, A549, HCT-116, and LO2, with respective IC50 values of 0.43, 0.036, 0.041, 0.095, and 1.04 μM. Additionally, IDO/Tubulin-IN-2 markedly enhances antitumor activity [1].

2-Amino-4-chloro-5-iodo-N2-pivaloyl-7-[2-deoxy-3,5-di-O- (4-methylbenzoyl)-b-D-ribofuanosyl]-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deazapurine nucleoside; Halo-nucleoside.

Methyl 2-(6-acetyl-5-hydroxy-2,3-dihydrobenzofuran-2-yl)propenoate is a natural product from Vernonia cinerea.

2-(4-Methoxyphenyl)naphtho[2,3-d]oxazole-4,9-dione is a Heterocyclic Compound and can be used in anticancer and antimicrobial studies.

Methyl 2-(2,3-dihydroxyphenyl)acetate is a useful organic compound for research related to life sciences and the catalog number is T125619.

2-Amino-4-chloro-N2-pivaloyl-7-[2-deoxy-3,5-di-O-(4- methylbenzoyl)-b-D-ribofuanosyl]-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deazapurine nucleoside; Halo-nucleoside.

Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides

(Z)-[2,3’-Biindolinylidene]-2’,3-dione is a useful organic compound for research related to life sciences. The catalog number is T64423 and the CAS number is 906748-38-7.

N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuriminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively). In vivo, DANA (30 μL of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.

Nucleoside Derivatives - 7-Deaza-purine nucleosides; 6-De-aminopurine nucleosides

2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.

2'-O-(2-Cyanoethoxy) (diisopropylamino)phosphino-3'-O-(4,4'-dimethoxy triphenyl)methyl-N2-isobutyryl-(R)-9-(2,3-dihydroxypropyl)-guanine is a Nucleoside Phosphoramidite.

Nucleoside Derivatives - 7-Deaza-purine nucleoside

(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate is a useful organic compound for research related to life sciences. The catalog number is T67219 and the CAS number is 1175536-50-1.

7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione is a useful organic compound for research related to life sciences. The catalog number is T64627 and the CAS number is 2252403-82-8.

2-p-Tolylnaphtho[2,3-d]oxazole-4,9-dione is a Heterocyclic Compound and can be used in anticancer and antimicrobial studies.

(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one is a useful organic compound for research related to life sciences. The catalog number is T65968 and the CAS number is 42399-49-5.

1-(Chloromethyl)-1-methyl-4-(2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-yl)-piperazinium chloride is a useful organic compound for research related to life sciences and the catalog number is T64494.

2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65734 and the CAS number is 138564-60-0.

(E)-2,3-Dibromo-2-butenedioic acid is a brominated haloacid that belongs to the category of drinking water disinfection byproducts (DBPs).

2-Norbornanamine, N,N,2,3-tetramethyl- is a Drug / Therapeutic Agent.

2',4'-Dihydroxy-2,3',6'-trimethoxychalcone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2713 and the CAS number is 100079-39-8. 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone can be used as a reference standard.

5-(2-Thioxo-2,3-dihydrothiazol-4-yl)thiophene-2-carboxamide is a useful organic compound for research related to life sciences and the catalog number is T64886.

(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetic acid is a useful organic compound for research related to life sciences. The catalog number is T65534 and the CAS number is 63422-71-9.

Nucleoside Derivatives - 2’-Modified nucleosides, 7-Deaza-purine nucleosides, Halo-nucleosides

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1024.

(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine, a purine nucleoside analogue, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms including DNA synthesis inhibition and apoptosis induction [1].

4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.

2-Norbornanamine, N,2,3-trimethyl- is a Drug / Therapeutic Agent.

Nucleoside Derivatives - 7-Deaza-purine nucleoside; Scaffolds an Templates

2-Norbornanamine, 2,3-dimethyl- is a Drug / Therapeutic Agent.

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1021.

4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.

5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one is a useful organic compound for research related to life sciences. The catalog number is T66785 and the CAS number is 4803-74-1.

4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.

(S)-2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine (2R,3R)-2,3-dihydroxysuccinate is a useful organic compound for research related to life sciences. The catalog number is T67217 and the CAS number is 210095-58-2.

Nucleoside; Used for nucleoside and nucleic acid modification

(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine is a Nucleoside Derivative - Acyclic nucleoside.

4-Amino-5-cyano-1-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy, particularly against indolent lymphoid malignancies. Its anticancer properties primarily stem from the inhibition of DNA synthesis and the induction of apoptosis, among other mechanisms [1].