protected

Protected meropenem is a useful organic compound for research related to life sciences. The catalog number is T66294 and the CAS number is 96036-02-1.

Nucleoside Derivatives - Anhydro-nucleosides; Protected nucleosides with NH2/OH group

Nesosteine Lithium is a novel mucoregulatory that inhibits Herxheimer microconvulsions in guinea pigs and inhibits ovalbumin-induced histamine release from sensitized trachea.Nesosteine Lithium protects against ovalbumin-induced bronchospasm but is ineffective against histamine- and acetylcholine-induced bronchospasm. Nesosteine Lithium protected against ovalbumin-induced bronchospasm but not histamine- and acetylcholine-induced bronchospasm.

Boc-Gly-Gly-Phe-Gly-OH acetate (GGFG acetate) is a self-assembly of N- and C-protected tetrapeptide.

Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS-induced NF-κB activation and inflammatory response. Alliin might be used as an anti-inflammatory agent in the treatment of ALI.

1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.

N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecules for later reaction with sulfhydryl reactive crosslinkers such as Sulfo-SMCC, Sulfo-MBS, etc.

Boc-D-Trp(For)-OH, a derivative of the amino acid tryptophan with pharmacological properties such as inhibition of growth hormone release, induction of sleep, and anti-inflammatory effects [1] [2], is synthesized through the ammonolysis of Boc-protected D-alanine, followed by cyclization with ninhydrin to form the dipeptide.

A component of bacterial cell walls. For a protected derivative of MurNAc see Q-1005.

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative containing a hydroxyl group and Boc-protected amino group, and is a PROTAC linker.

Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 value of 10.46μM. Irilone potentiat

Boc-Gly-Gly-Phe-Gly-OH TFA is a self-assembly of N-protected and C-protected tetrapeptides and is a protease cleaved connector for antibody-drug binding (ADC).

Fmoc-Phe(4-CN)-OH is an N-Fmoc protected phenylalanine derivative and potentially useful synthetic intermediate

FMoc-Arg(Tos)-OH is a synthetic amino acid used in peptide synthesis, biochemistry and molecular biology. It is a Fmoc-protected amino acid used as an intermediate in peptide and protein synthesis for solid-phase peptide synthesis.

MN714 is a pivaloyloxymethyl-protected inhibitor (POM-protected inhibitor) [1].

Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, respectively. Mn(III)TMPyP protected and enhanced the growth of SOD E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 µM.

5'-O-Triphenylmethyl-2'-deoxyuridine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

5'-O-Benzoyl-2'-O,4'-C-methyleneuridine is a Nucleoside Derivative - LNA related nucleoside; Protected nucleoside with NH2/OH open.

Nucleoside Derivatives - 3’-Modified nucleosides; Protected nucleosides w/NH/OH open

9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

3'-O-(t-Butyldiphenylsilyl)thymidine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open.

Hydroxy-PEG12-t-butyl ester is a PEG derivative containing a hydroxyl group and a t-butyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Under acidic conditions, the t-butyl protected carbox

Amino-PEG3-t-butyl ester is a PEG derivative containing an amino group with the t-butyl protected carboxyl group. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides, Protected nucleosides with NH2/OH open

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides,2’-Modified nucleosides; Protected nucleosides with NH2/OH group

Nucleoside Derivatives - 3’-Modified nucleosides; Protected nucleosides with NH2/OH open; Ready for phosphorylation

Nucleoside Derivatives - Fluoro-modified nucleosides; 3’-Modified nucleosides; Protected nucleosides w/NH2/OH open

Nucleoside Derivatives - Thio-nucleosides; Protected nucleosides w/NH2/OH open; 2’-Modified nucleosides

5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside; Protected nucleoside with NH2/OH open; Ready for further phosphorylation.

Fmoc-ε-Acp-OH can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-ε-Acp-OH is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-Methyl guanosine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

Pemetrexed Diethyl Ester is a protected intermediate in the synthesis of Pemetrexed, a multi-targeted anti-folate that inhibits thymidylate synthase as well as other folate dependent enzymes.

5'-O-(4,4'-Dimethoxytrityl)-3'-O-(2-methoxyethyl) uridine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

Nucleosides Derivatives - Protected nucleosides with NH2/OH group

4'-alpha-C-Allyl-2',3'-bis(O-t-butyldimethylsilyl)uridine is a Nucleoside Derivative - 4'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

3',5'-TIPS-N-PAc-Guanosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

Nucleoside Derivatives - Halo-nucleoside; 2’-Modified nucleoside, Protected nucleosides with NH2/OH open

Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Nucleoside Derivatives - L-Nucleosides; Protected nucleosides w/NH2/OH open

Nucleoside Derivatives - Protected nucleosides with NH2/OH open, 2’-Modified nucleosides

2'-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group.

Azido-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.

3',5'-TIPS-N-Ac-Adenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.

Propargyl - peg2-tert-butyl ester is a PEG derivative containing propargyl and tert-butyl protected carboxyl groups.

Tryptophan is an amino acid precursor of serotonin and melatonin. DL-Tryptophan octyl ester is a tryptophan derivative with an octyl ester protected COOH group. This addition creates a stable, cell-permeable molecule capable of generating free tryptophan upon hydrolysis of the ester bond.

Fmoc-4-aminobutanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-4-aminobutanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Nucleoside Derivatives - Xylo-nucleosides, 2’-Deoxy-nucleosides; ; Protected nucleosides with NH2/OH group

Nucleoside Derivatives - 6-Modified purine nucleosides; Protected nucleosides w/NH2/OH open