DNA Alkylator/Crosslinker

Cat. No.	Product name	CAS No.	Purity
T22857	Illudin S	1149-99-1	98%
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
T17212	VAL-083	23261-20-3
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
T4558	Trioxsalen	3902-71-4	100%
Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation ...
T4459	PK11000	38275-34-2	100%
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
T1488	Procarbazine hydrochloride	366-70-1	85.01%
Procarbazine Hydrochloride is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cyt...
T4570	Pipobroman	54-91-1	93.01%
Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essen...
T4350	Palifosfamide	31645-39-3	97%
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
T8380	Bendamustine	16506-27-7	97.38%
Bendamustine for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
T7221	Satraplatin	129580-63-8	98%
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...
T4368	Miriplatin	141977-79-9	98%
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
T0707	Cyclophosphamide hydrate	6055-19-2	98%
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T17159	Treosulfan	299-75-2	98%
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
T0095	Bendamustine hydrochloride	3543-75-7	98.03%
Bendamustine hydrochloride (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
T1798	RITA	213261-59-7	98.85%
RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 i...
T1250	Thio-TEPA	52-24-4	99.07%
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
T5017	Nimustine Hydrochloride	55661-38-6	99.2%
Nimustine has been used in trials studying the treatment of Glioblastoma.
T1507	Streptozocin	18883-66-4	99.56%
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
T0975	Chlorambucil	305-03-3	99.58%
Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, result...
T1564	Cisplatin	15663-27-1	99.62%
Cisplatin, a DNA-crosslinking agent, is able to suppress DNA synthesis by conforming DNA adducts in cancer cells.
T0164	Oxaliplatin	61825-94-3	99.63%
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T22857

Illudin S

1149-99-1

98%

Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.

T17212

VAL-083

23261-20-3

VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.

T4558

Trioxsalen

3902-71-4

100%

Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation ...

T4459

PK11000

38275-34-2

100%

PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.

T1488

Procarbazine hydrochloride

366-70-1

85.01%

Procarbazine Hydrochloride is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cyt...

T4570

Pipobroman

54-91-1

93.01%

Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essen...

T4350

Palifosfamide

31645-39-3

97%

Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...

T8380

Bendamustine

16506-27-7

97.38%

Bendamustine for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia

T7221

Satraplatin

129580-63-8

98%

Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...

T4368

Miriplatin

141977-79-9

98%

Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).

T0707

Cyclophosphamide hydrate

6055-19-2

98%

Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.

T17159

Treosulfan

299-75-2

98%

Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.

T0095

Bendamustine hydrochloride

3543-75-7

98.03%

Bendamustine hydrochloride (IC50 of 50 μM) is an alkylating agent associated with DNA damage.

T1798

RITA

213261-59-7

98.85%

RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 i...

T1250

Thio-TEPA

52-24-4

99.07%

Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.

T5017

Nimustine Hydrochloride

55661-38-6

99.2%

Nimustine has been used in trials studying the treatment of Glioblastoma.

T1507

Streptozocin

18883-66-4

99.56%

Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...

T0975

Chlorambucil

305-03-3

99.58%

Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, result...

T1564

Cisplatin

15663-27-1

99.62%