T3091 |
Carmustine
|
154-93-8
|
99.97%
|
|
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.
|
T0164 |
Oxaliplatin
|
61825-94-3
|
99.93%
|
|
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcr...
|
T8554 |
KCC-07
|
315702-75-1
|
99.93%
|
|
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD...
|
T1601 |
Lomustine
|
13010-47-4
|
99.86%
|
|
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.
|
T0923 |
Busulfan
|
55-98-1
|
99.77%
|
|
Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully...
|
T6798 |
Tretazicar
|
21919-05-1
|
99.7%
|
|
CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and ...
|
T0707 |
Cyclophosphamide hydrate
|
6055-19-2
|
99.65%
|
|
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
|
T0975 |
Chlorambucil
|
305-03-3
|
99.58%
|
|
Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cyc...
|
T16871 |
Semustine
|
13909-09-6
|
99.55%
|
|
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for ...
|
T1564 |
Cisplatin
|
15663-27-1
|
99.54%
|
|
Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also...
|
T1058 |
Carboplatin
|
41575-94-4
|
99.43%
|
|
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death...
|
T17159 |
Treosulfan
|
299-75-2
|
99.26%
|
|
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
T5017 |
Nimustine Hydrochloride
|
55661-38-6
|
99.2%
|
|
Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.
|
T4558 |
Trioxsalen
|
3902-71-4
|
98.96%
|
|
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After ph...
|
T4169 |
N-Nitroso-N-methylurea
|
684-93-5
|
98.78%
|
|
N-Nitroso-N-methylurea (Methylnitrosourea) is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
|
T1178 |
Temozolomide
|
85622-93-1
|
98.43%
|
|
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic acti...
|
T22857 |
Illudin S
|
1149-99-1
|
98.15%
|
|
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
|
T0095 |
Bendamustine hydrochloride
|
3543-75-7
|
98.03%
|
|
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
|
T4368 |
Miriplatin
|
141977-79-9
|
98%
|
|
Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
|
T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|