T11614 |
IDO-IN-11 |
IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell). |
T11615 |
IDO-IN-12 |
IDO-IN-12 is an indoleamine 2,3-dioxygenase (IDO) inhibitor. |
T11617 |
IDO-IN-3 |
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM. |
T11619 |
IDO-IN-5 |
IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor, has an IC50 of 1-10 μM. |
T11620 |
IDO-IN-6 |
IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor. |
T11621 |
IDO-IN-8 |
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor , has an IC50 of 1-10 μM. |
T11622 |
IDO-IN-9 |
IDO-IN-9 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.011 μM (Kinase) and 0.0018 μM (Hela Cell). |
T11624 |
IDO1-IN-2 |
IDO1-IN-2 has anti-cancer activity. IDO1-IN-2 is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse) and 28 nM (rat), respectively. |
T11626 |
IACS-8968 |
IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. |
T11627 |
IACS-8968 R-enantiomer |
IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. IACS-8968 is the R-enantiomer of IACS-8968. |
T11628 |
IACS-8968 S-enantiomer |
IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. IACS-8968 is the S-enantiomer of IACS-8968. |
T11901 |
IDO1-IN-5 |
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. |
T1806 |
NLG919 |
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor. |
T2647 |
INCB024360 analogue |
IDO-IN-2 is an effective IDO1 inhibitor(IC50=10 nM). |
T3548 |
Epacadostat |
Epacadostat is an oral-available inhibitor of indoleamine 2,3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reduc...
|
T4142 |
DO-IN-2 |
IDO-IN-2 is an IDO inhibitor extracted from patent WO/2015031295 A1, compound example 1. |
T4307 |
PF-06840003 |
PF-06840003 is a specific and oral active IDO-1 inhibitor. |
T4532 |
Linrodostat |
BMS-986205 is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor. |
T5S0053 |
Coptisine |
1. Coptisine treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2,3-dioxygenase . 2. Coptisine treats myoca...
|
T5S0056 |
Coptisine chloride |
1. Coptisine chloride can be absorbed across intestinal epithelial cells, and completely absorbed compounds. |
T6407 |
Beta-Lapachone |
Beta-Lapachone is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase. |
T6543 |
Indoximod |
Indoximod is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades...
|
T8214 |
Flemiphilippinin D |
Kushenol E is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 µM, Ki: 9.5 µM), has anti-tumor ac...
|
TQ0071 |
Navoximod |
Navoximod (NLG-919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM). |