MRP

Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance in tumor cells by extruding anticancer drugs out of the cell.

Cat No.	product name
T0291	Flurbiprofen	Flurbiprofen is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal dise...
T4A2399	Cinobufotalin	Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide pr...
T1484L	Perindopril erbumine	Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihyper...
T19866	Indican	Indican is a natural protective compound that is used to protect the liver.
T0450	Fluoxetine	Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
T0707	Cyclophosphamide hydrate	Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T0839	Ketoprofen	Ketoprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inh...
T1434	Clarithromycin	Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, a...
T1050	Prazosin hydrochloride	Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not complete...
T1130	Gramicidin	A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is ...
T0791	Reserpine	Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resul...
T0760	Cholesterol	Cholesterol is the primary sterol in mammals. The significance of Cholesterol is becoming more appreciated in fundamental cellular processes.
T1571	Estriol	Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
T0924	Benzocaine	Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
TN1863	Licoisoflavone A	Licoisoflavone A is a potential MRP inhibitor, it shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro.
TN2219	Sophoraisoflavone A	Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tu...
T8596	Ceefourin 1	Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
T0866	Propafenone	Propafenone is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmi...
T0706	Lisinopril dihydrate	Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1484	Perindoprilat	Perindoprilat is an angiotensin-converting enzyme inhibitor.
T1605	Enalapril	Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T9982	PU23	PU 23 是一种多药抗性蛋白4(MRP4)的抑制剂。