T12330 |
OT-82
|
1800487-55-1
|
98%
|
|
OT-82 is a potent, selective and orally active NAMPT inhibitor.
|
T15403 |
GNE-618
|
1362151-42-5
|
98%
|
|
GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM). GNE-618 depletes NAD levels and induces tumor cell death....
|
T11823 |
LB-60-OF61
|
794461-93-1
|
98%
|
|
LB-60-OF61, a NAMPT inhibitor, is a cytotoxic compound that is selective to MYC overexpressed cell lines.
|
T12854 |
SBI-797812
|
2237268-08-3
|
98%
|
|
SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
|
T6682 |
STF-118804
|
894187-61-2
|
98%
|
|
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
|
T12171 |
Nampt-IN-5
|
2380013-17-0
|
98%
|
|
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
|
T4376 |
Nampt-IN-1
|
1698878-14-6
|
98%
|
|
Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
|
T1998 |
CHS-828
|
200484-11-3
|
98%
|
|
GMX1778(CHS-828), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).
|
T4354 |
KPT9274
|
1643913-93-2
|
98%
|
|
KPT-9274 is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.
|
T2644 |
(E)-Daporinad
|
658084-64-1
|
98%
|
|
Daporinad is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activities.
|
T4335 |
GNE-617
|
1362154-70-8
|
98%
|
|
GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.
|
T67925 |
Nampt activator-1
|
701929-65-9
|
98%
|
|
NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 μM). NAMP...
|