NAMPT

Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin is an enzyme that in humans is encoded by the NAMPT gene. This protein is the rate-limiting enzyme in the Nicotinamide adenine dinucleotide (NAD+) salvage pathway that converts nicotinamide to nicotinamide mononucleotide in mammals to enable NAD+ biosynthesis. NAMPT has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis.

Cat. No.	Product name	CAS No.	Purity
T12330	OT-82	1800487-55-1	98%
T12330	OT-82 is a potent, selective and orally active NAMPT inhibitor.
T15403	GNE-618	1362151-42-5	98%
T15403	GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM). GNE-618 depletes NAD levels and induces tumor cell death....
T11823	LB-60-OF61	794461-93-1	98%
T11823	LB-60-OF61, a NAMPT inhibitor, is a cytotoxic compound that is selective to MYC overexpressed cell lines.
T12854	SBI-797812	2237268-08-3	98%
T12854	SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
T6682	STF-118804	894187-61-2	98%
T6682	STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
T12171	Nampt-IN-5	2380013-17-0	98%
T12171	Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
T4376	Nampt-IN-1	1698878-14-6	98%
T4376	Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
T1998	CHS-828	200484-11-3	98%
T1998	GMX1778(CHS-828), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).
T4354	KPT9274	1643913-93-2	98%
T4354	KPT-9274 is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.
T2644	(E)-Daporinad	658084-64-1	98%
T2644	Daporinad is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activities.
T4335	GNE-617	1362154-70-8	98%
T4335	GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.
T67925	Nampt activator-1	701929-65-9	98%
T67925	NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 μM). NAMP...