Neurotensin Receptor

The neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the SORT1 gene.

Cat. No.	Product name	CAS No.	Purity	Chemical Structure
T7617	Neurotensin(8-13)	60482-95-3
T7617	Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
T23386	SR 142948	184162-64-9
T23386	SR 142948 is a neurotensin (NT) receptor antagonist.
T78954	HNTS1R agonist-1		98%
T78954	Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (B...
T79105	BVFP	357158-20-4	98%
T79105	BVFP exhibits affinity for the PGRN 588–593 peptide through binding with a dissociation constant (Kd) of 20 μM and is capable of disrupting the interaction betwe...
T79106	SORT-PGRN interaction inhibitor 3	2691846-87-2	98%
T79106	SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study o...
TQ0075	ML314	1448895-09-7	98%
TQ0075	ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).
TP2104L	UFP 803 acetate		99.78%
TP2104L	UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist.
T16860	SBI-553	1849603-72-0	99.69%
T16860	SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
T28217	NTRC-844	1811503-67-9	99.61%
T28217	NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.
T9044	SORT-PGRN interaction inhibitor 1	100957-85-5	99.56%
T9044	SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
TQ0086	AF38469	1531634-31-7	99.56%
TQ0086	AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
T22476	(±)-AC 7954 hydrochloride	477313-09-0	99.42%
T22476	(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.
T23323	SB 611812	345892-71-9	99.34%
T23323	SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about the treatment of cardiovascular disease.
TP2106L	Urantide acetate(669089-53-6 free base)	TP2106L	99.22%
TP2106L	Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. E...
T12848	SB-657510	474960-44-6	98.03%
T12848	SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively...
T7617L	Neurotensin(8-13) 3TFA(60482-95-3(free base))	2952825-79-3	100%
T7617L	Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
TP1116L	Kinetensin acetate(103131-69-7 free base)	TP1116L	100%
TP1116L	Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
TP1310	Neurotensin	39379-15-2	100%
TP1310	Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction wit...
T38807L	[Lys8, Lys9]-Neurotensin (8-13) acetate		98%
T38807L	[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, ...
T77053	Latozinemab		98%	Latozinemab
T77053	Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interru...			Latozinemab