Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the ...
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay). |
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis. |
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals. |
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM). |
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infectio...
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination. |
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay). |
Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activ...
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase...
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibito...