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DNA Damage/DNA Repair Telomerase

Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of eukaryotic chromosomes in most eukaryotes.
Cat No. product name
T1416 Zidovudine Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the ...
T2380 BIBR 1532 BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
T2902 Costunolide Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T3333 Cycloastragenol Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
T7409 360A 360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
T7447 Adefovir Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infectio...
T3182 L-778123 hydrochloride The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
T13504 360A iodide 360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
T13115 Telomerase-IN-2 Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activ...
T10574 BMVC BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase...
TN4443 Lipiferolide Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibito...
Zidovudine
T1416CAS 30516-87-1
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the ...
BIBR 1532
T2380CAS 321674-73-1
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
Costunolide
T2902CAS 553-21-9
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
Cycloastragenol
T3333CAS 84605-18-5
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
360A
T7409CAS 794458-56-3
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
Adefovir
T7447CAS 106941-25-7
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infectio...
L-778123 hydrochloride
T3182CAS 253863-00-2
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
360A iodide
T13504CAS 737763-37-0
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
Telomerase-IN-2
T13115CAS 1610878-54-0
Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activ...
BMVC
T10574CAS 627810-06-4
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase...
Lipiferolide
TN4443CAS 41059-80-7
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibito...