Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the ...
BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.