Thyroid hormone receptor(THR)

The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone.TRs act as transcription factors, ultimately affecting the regulation of gene transcription and translation. These receptors also have non-genomic effects that lead to second messenger activation, and corresponding cellular response.

Cat. No.	Product name	CAS No.	Purity
T15644	KAT681	373641-87-3	98%
T15644	KAT681 is a liver selective thyromimetic.
T10855	CO23	1370363-74-8	98%
T10855	CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.
T7590	Taltirelin	103300-74-9	98%
T7590	Taltirelin is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ conc...
T15699	L-Thyroxine sodium salt pentahydrate	6106-07-6	98%
T15699	L-Thyroxine sodium salt pentahydrate is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodot...
TP1022	Protirelin Acetate	120876-23-5	98%
TP1022	Protirelin Acetate is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
T6956	Protirelin	24305-27-9	98%
T6956	Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
T9691L	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate		98%
T9691L	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membr...
TP1906L1	DPC AJ1951 acetate	TP1906L1	98%
TP1906L1	DPC-AJ1951 acetate, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized ...
T13492	3,5-Diiodothyropropionic acid	1158-10-7	98%
T13492	3,5-Diiodothyropropionic acid is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.0...
T40548	NH-3	447415-26-1	98%
T40548	NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC 50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, in...
T6956L	Protirelin Acetate(24305-27-9 free base)	T6956L	100%
T6956L	Protirelin Acetate is a tripeptide that stimulates the release of thyrotropin and prolactin.
T16018	MB-07811	852948-13-1	97.28%
T16018	MB-07811 is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targeted THR-β.
T7578	REVERSE T3	5817-39-0	97.66%
T7578	reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
T1669	Liothyronine sodium	55-06-1	98%
T1669	Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyron...
T5360	Eprotirome	355129-15-6	98.29%
T5360	Eprotirome, a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
T23673	AH-3960	862907-48-0	98.44%
T23673	AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist.
T0864	L-Thyroxine	51-48-9	98.64%
T0864	Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling o...
T5313	Sobetirome	211110-63-3	98.72%
T5313	Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T3595	Resmetirom	920509-32-6	99.13%
T3595	MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist.
T0952	Carbimazole	22232-54-8	99.22%
T0952	Carbimazole is an imidazole antithyroid agent. It is only found in individuals that have used or taken this drug. Carbimazole is metabolized to methimazole, whic...