Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T60889 | RP-6306 | 2719793-90-3 | 98% |
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RP-6306 is a potent, selective and orally active PKMYT1 inhibitor (IC50= 14 nM). RP-6306 exhibits a high degree of selectivity for PKMYT1 over other kinases in c... | ||||
T9864 | Debio-0123 | 2243882-74-6 | 98% |
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Debio-0123 is a potent Wee1 inhibitor with an IC50 value of 0.8 nM. Debio-0123 inhibits phospho-CDC2. Debio-0123 abrogates the G2 check point, increasing sensiti... | ||||
T8916 | WEE1-IN-3 | 2272976-28-8 | 98.61% |
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JUN76288 is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases. | ||||
T9643 | ZN-c3 | 2376146-48-2 | 98.97% |
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ZN-c3 is a potent and selective Wee1 inhibitor with balanced potency, ADME, and pharmacokinetic properties. | ||||
T2077 | Adavosertib | 955365-80-7 | 99.58% |
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MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint. | ||||
T6931 | PD0166285 | 185039-89-8 | 99.59% |
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PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator. |