Home Tools

c-Fms

Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded, in humans, by the CSF1R gene (known also as c-FMS). It is a receptor for a cytokine called colony stimulating factor 1.

Cat. No.	Product name	CAS No.	Purity
T1925	PLX647	873786-09-5
T1925	PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
T78603	Sotuletinib dihydrochloride	2222138-40-9	98%
T78603	Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM. It pr...
T79472	CSF1R-IN-17		98%
T79472	CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM. It is capable of inhib...
T79815	C-Fms-IN-14	1898210-99-5	98%
T79815	c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].
T80585	Anti-Mouse GM-CSF Antibody (MP1-22E9)		98%
T80585	Anti-Mouse GM-CSF Antibody is a rat-derived IgG2a isotype inhibitor that targets mouse granulocyte-macrophage colony-stimulating factor (GM-CSF).
T10648	C-Fms-IN-9	1628574-50-4	98%
T10648	c-Fms-IN-9 is a c-FMS inhibitor. It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).
T69759	IACS-9439	2231259-57-5	98%
T69759	IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM. It is applicable in the research of advanced solid tumors [1]....
T12505	PLX5622 hemifumarate	T12505	98%
T12505	PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor with an IC 50 of 0.016 μM and Ki of 5.9 nM. PLX5622 hemifumarate all...
T10645	C-Fms-IN-6	1628574-81-1	98%
T10645	c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).
T10649	C-Fms-IN-3	885704-21-2	99.92%
T10649	c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.
T2609	Masitinib	790299-79-5	99.91%
T2609	Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 200...
T10643	C-Fms-IN-1	885703-64-0	99.88%
T10643	c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).
T5586	CFMS Receptor Inhibitor II	959860-85-6	99.86%
T5586	cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor
T61589	C-Fms-IN-13	885704-58-5	99.83%
T61589	c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.
T79157	Pimicotinib	2253123-16-7	99.8%
T79157	Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.
T2624	OSI-930	728033-96-3	99.76%
T2624	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel ...
T60087	CFMS Receptor Inhibitor IV	959626-45-0	99.73%
T60087	cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.
TQ0015	PRN1371	1802929-43-6	99.72%
TQ0015	PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).
T13194	CSF1R-IN-2	2271119-26-5	99.71%
T13194	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).
T6930	Pazopanib Hydrochloride	635702-64-6	99.69%
T6930	Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM...