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Search Results for " abeta "

Targets

44

Compounds

18

Natural Products

12

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7527 Frentizole Beta Amyloid
Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction
T3259 FPS-ZM1 Beta Amyloid , advanced glycation end products
FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.
T22694 CRANAD 2 Others
CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-f...
T12532 PQM130 Beta Amyloid
PQM130 is a neuroprotective compound ,and is a potential anti-AD drug.
TP1856 Colivelin Beta Amyloid , STAT
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
T7905 PBD-150 Beta Amyloid
PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
T5447 Anle138b Beta Amyloid , Others
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease
T7490 ARN2966 Beta Amyloid
ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.
T21825 TAE-1 Beta Amyloid , AChE
TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
T4364 Aftin-4 Aftin 4,Aftin4 Beta Amyloid , Gamma-secretase
Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus...
T21890 JLK6 Gamma-secretase
JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling
T14199 ALZ-801 Valiltramiprosate Beta Amyloid
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-m...
T4398 LX2343 Beta Amyloid , Beta-Secretase , BACE , PI3K , Autophagy
LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.
T11043 Dihydroergocristine mesylate DHEC (mesylate) Beta Amyloid
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebro...
T6125 Semagacestat LY450139 Beta Amyloid , Gamma-secretase
Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).
TQ0026 MDR-1339 DWK-1339 Beta Amyloid , Gamma-secretase
MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.
T2507 Azeliragon TTP488 Beta Amyloid , advanced glycation end products
Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-moderate Alzheimer_acute_s disease (AD).
T6202 DAPT LY-374973,GSI-IX Apoptosis , Beta Amyloid , Gamma-secretase , Autophagy
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.
T6708 Tolcapone Tasmar,Ro 40-7592 Apoptosis , Beta Amyloid , Transferase
Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.
T4422 Edonerpic maleate T-817MA,T-817 maleate Beta Amyloid
Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).
T29856 Aleplasinin PAZ 417,PAZ417,PAZ-417 PAI-1
Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...
T63208L Aβ-IN-1 TFA Aβ-IN-1 TFA(2766509-32-2 Free base)
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.
T6562 Latrepirdine dihydrochloride Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin Beta Amyloid , 5-HT Receptor , Adrenergic Receptor , GluR , Autophagy , Histamine Receptor
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.
T9713 δ-secretase inhibitor 11 Beta Amyloid , Caspase
δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.
T39781 Aβ/tau aggregation-IN-1
Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can pe...
T14284 β-Amyloid (25-35) β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35) Beta Amyloid
β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
T19011 Hoechst 34580 HOE 34580 Beta Amyloid
Hoechst 34580 (HOE 34580), a cell-permeable fluorescent dye, is used for staining DNA and nuclei.
T7562 β-Amyloid (31-35) β-Amyloid 31-35(TFA),β-Amyloid 31-35 Beta Amyloid
β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.
T7003 Leucomethylene blue mesylate TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate Beta Amyloid , Microtubule Associated
Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
TP1007 β-Amyloid (1-42), human β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human Beta Amyloid
Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
T0348 Labetalol hydrochloride Sch-15719W,AH-5158 hydrochloride,Labetalol HCl Adrenergic Receptor
Labetalol hydrochloride (Sch-15719W), a salicylamide derivative, is a non-cardioselective blocker of β-adrenergic receptors and α1-adrenergic receptors.
T5642 Tegatrabetan BC2059 Wnt/beta-catenin
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
T20570 Labetalol Apo-Labetalol,Albetol,Trandate,Dilevalol,Normodyne Adrenergic Receptor
Labetalol (Apo-Labetalol) is a mixed alpha/beta-adrenergic antagonist.It is used to treat high blood pressure. It can be given by mouth for long term hypertension management or intravenously in severe hypertensive situat...
T2480 Apabetalone RVX-208,RVX000222 Epigenetic Reader Domain , HIV Protease
Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery disease.
T35326 Labetalone hydrochloride Labetalone hydrochloride,Benzoic amide Others
Labetalone hydrochloride (Benzoic amide) is an impurity of Labetalol. Labetalol is an orally active adrenoceptor blocking drug, Labetalol is a competitive antagonist at both alpha- and beta-adrenoceptor sites
T22932L LPYFD-NH2 acetate LPYFD-NH2 acetate (700361-48-4 free base) Beta Amyloid
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).
T77054 Lecanemab BAN-2401 Beta Amyloid
Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated β-amyloid (Abeta) with activity against oligomers, protofibrils, and insoluble protofibrils, and may be useful in the study of Alzheimer's ...
T37621 Ezeprogind disulfate Beta Amyloid
Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta protein or tau protein. Ezeprogind disulfate can be used for the research of neurological disor...
T31801 Florbetapir F-18
Florbetapir F-18 is a PET agent for Abeta plaques.
T76666 β-Amyloid peptide(16-20)
β-Amyloid peptide(16-20) is a amino acid sequences (KLVFF) of Amyloid-β (Abeta). β-Amyloid peptide(16-20) is an effective inhibitor of Abeta fibril formation, with RG-/-GR-NH 2 residues added at N- and C-terminal ends to...
T80701 β Amyloid (1-16) rat
β-Amyloid (1-16) rat is a fragment of the metal-binding domain of the amyloid beta (Abeta) peptide. It contains three amino acid substitutions that distinguish it from its human counterpart, conferring reduced susceptibi...
T80700 β Amyloid(17-28) human
β-Amyloid(17-28) human is a fragment of the β-amyloid peptide (Abeta) associated with Alzheimer's disease (AD), promoting the aggregation of the full-length β-Amyloid40 into toxic aggregates [1]. This lipid-induced amylo...
TP1673 β-Amyloid (11-22) β-Amyloid 11-22
β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). A...
T40701 Ezeprogind AZP-2006
Ezeprogind (AZP-2006) is an orally active neurotrophic inducer that effectively addresses the underlying factors contributing to neurodegeneration, with a broad scope extending beyond the conventional targets like Abeta ...

Compounds

Frentizole
T7527
Synonym:
Target: Beta Amyloid
FPS-ZM1
T3259
Synonym:
Target: Beta Amyloid, advanced glycation end products
CRANAD 2
T22694
Synonym:
Target: Others
PQM130
T12532
Synonym:
Target: Beta Amyloid
Colivelin
TP1856
Synonym:
Target: Beta Amyloid, STAT
PBD-150
T7905
Synonym:
Target: Beta Amyloid
Anle138b
T5447
Synonym:
Target: Beta Amyloid, Others
ARN2966
T7490
Synonym:
Target: Beta Amyloid
TAE-1
T21825
Synonym:
Target: Beta Amyloid, AChE
Aftin-4
T4364
Synonym: Aftin 4,Aftin4
Target: Beta Amyloid, Gamma-secretase
JLK6
T21890
Synonym:
Target: Gamma-secretase
ALZ-801
T14199
Synonym: Valiltramiprosate
Target: Beta Amyloid
LX2343
T4398
Synonym:
Target: Beta Amyloid, Beta-Secretase, BACE, PI3K, Autophagy
Dihydroergocristine mesylate
T11043
Synonym: DHEC (mesylate)
Target: Beta Amyloid
Semagacestat
T6125
Synonym: LY450139
Target: Beta Amyloid, Gamma-secretase
MDR-1339
TQ0026
Synonym: DWK-1339
Target: Beta Amyloid, Gamma-secretase
Azeliragon
T2507
Synonym: TTP488
Target: Beta Amyloid, advanced glycation end products
DAPT
T6202
Synonym: LY-374973,GSI-IX
Target: Apoptosis, Beta Amyloid, Gamma-secretase, Autophagy
Tolcapone
T6708
Synonym: Tasmar,Ro 40-7592
Target: Apoptosis, Beta Amyloid, Transferase
Edonerpic maleate
T4422
Synonym: T-817MA,T-817 maleate
Target: Beta Amyloid
Aleplasinin
T29856
Synonym: PAZ 417,PAZ417,PAZ-417
Target: PAI-1
Aβ-IN-1 TFA
T63208L
Synonym: Aβ-IN-1 TFA(2766509-32-2 Free base)
Target:
Latrepirdine dihydrochloride
T6562
Synonym: Dimebolin dihydrochloride,Latrepirdine,Latrepirdine 2HCl,Dimebolin
Target: Beta Amyloid, 5-HT Receptor, Adrenergic Receptor, GluR, Autophagy, Histamine Receptor
δ-secretase inhibitor 11
T9713
Synonym:
Target: Beta Amyloid, Caspase
Aβ/tau aggregation-IN-1
T39781
Synonym:
Target:
β-Amyloid (25-35)
T14284
Synonym: β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35)
Target: Beta Amyloid
Hoechst 34580
T19011
Synonym: HOE 34580
Target: Beta Amyloid
β-Amyloid (31-35)
T7562
Synonym: β-Amyloid 31-35(TFA),β-Amyloid 31-35
Target: Beta Amyloid
Leucomethylene blue mesylate
T7003
Synonym: TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate
Target: Beta Amyloid, Microtubule Associated
β-Amyloid (1-42), human
TP1007
Synonym: β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human
Target: Beta Amyloid
Labetalol hydrochloride
T0348
Synonym: Sch-15719W,AH-5158 hydrochloride,Labetalol HCl
Target: Adrenergic Receptor
Tegatrabetan
T5642
Synonym: BC2059
Target: Wnt/beta-catenin
Labetalol
T20570
Synonym: Apo-Labetalol,Albetol,Trandate,Dilevalol,Normodyne
Target: Adrenergic Receptor
Apabetalone
T2480
Synonym: RVX-208,RVX000222
Target: Epigenetic Reader Domain, HIV Protease
Labetalone hydrochloride
T35326
Synonym: Labetalone hydrochloride,Benzoic amide
Target: Others
LPYFD-NH2 acetate
T22932L
Synonym: LPYFD-NH2 acetate (700361-48-4 free base)
Target: Beta Amyloid
Lecanemab
T77054
Synonym: BAN-2401
Target: Beta Amyloid
Ezeprogind disulfate
T37621
Synonym:
Target: Beta Amyloid
Florbetapir F-18
T31801
Synonym:
Target:
β-Amyloid peptide(16-20)
T76666
Synonym:
Target:
β Amyloid (1-16) rat
T80701
Synonym:
Target:
β Amyloid(17-28) human
T80700
Synonym:
Target:
β-Amyloid (11-22)
TP1673
Synonym: β-Amyloid 11-22
Target:
Ezeprogind
T40701
Synonym: AZP-2006
Target:
Cat No. Product Name Synonyms Targets
TN6919 Methyl tridecanoate Beta Amyloid , AChE
Methyl tridecanoate is a natural product.
T2212 Geniposide Beta Amyloid , Influenza Virus
Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation...
T3914 Saikosaponin C Beta Amyloid , Caspase
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
T8012 Scyllo-Inositol Scyllitol Beta Amyloid , Endogenous Metabolite
Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for Alzheimer's disease.
T4S0350 Licochalcone B Beta Amyloid , Others
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...
TMS1461 Qingyangshengenin B Otophylloside B Beta Amyloid
Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...
T0795 Rutin Quercetin 3-O-rutinoside,Rutoside Beta Amyloid , Prostaglandin Receptor , Autophagy
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
T6S1918 Schisantherin B Gomisin-B,Wuweizi ester-B,Schizantherin-B Beta Amyloid , Others
1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
T22417 Rutin hydrate Rutoside,Sophorin,Quercetin-3-O-rutinoside Beta Amyloid , Others , Autophagy
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.
T0883 Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed Beta Amyloid , GABA Receptor
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...
T1686 Hematoxylin Hydroxybrazilin,Natural Black 1,Haematoxylin Beta Amyloid , Others
Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.
T2872 Ginsenoside Re Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.
T2961 Notoginsenoside R1 Sanqi glucoside R1,Sanchinoside R1 Apoptosis , ERK , Beta Amyloid
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.
T2777 Ginsenoside Rg1 Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2 Apoptosis , Beta Amyloid , NF-κB
Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level i...
T2873 Ginsenoside Rg2 Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2 Beta Amyloid , GSK-3 , NF-κB
Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.
T3402 20(S)-Ginsenoside Rg3 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3 EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
TN1653 Fustin ERK , Beta Amyloid , AChR
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.
T14305 Apicidin OSI 2040 Apoptosis , HDAC , Autophagy
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis ...

Natural Products

Methyl tridecanoate
TN6919
Synonym:
Target: Beta Amyloid, AChE
Geniposide
T2212
Synonym:
Target: Beta Amyloid, Influenza Virus
Saikosaponin C
T3914
Synonym:
Target: Beta Amyloid, Caspase
Scyllo-Inositol
T8012
Synonym: Scyllitol
Target: Beta Amyloid, Endogenous Metabolite
Licochalcone B
T4S0350
Synonym:
Target: Beta Amyloid, Others
Qingyangshengenin B
TMS1461
Synonym: Otophylloside B
Target: Beta Amyloid
Rutin
T0795
Synonym: Quercetin 3-O-rutinoside,Rutoside
Target: Beta Amyloid, Prostaglandin Receptor, Autophagy
Schisantherin B
T6S1918
Synonym: Gomisin-B,Wuweizi ester-B,Schizantherin-B
Target: Beta Amyloid, Others
Rutin hydrate
T22417
Synonym: Rutoside,Sophorin,Quercetin-3-O-rutinoside
Target: Beta Amyloid, Others, Autophagy
Tramiprosate
T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed
Target: Beta Amyloid, GABA Receptor
Hematoxylin
T1686
Synonym: Hydroxybrazilin,Natural Black 1,Haematoxylin
Target: Beta Amyloid, Others
Ginsenoside Re
T2872
Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re
Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK
Notoginsenoside R1
T2961
Synonym: Sanqi glucoside R1,Sanchinoside R1
Target: Apoptosis, ERK, Beta Amyloid
Ginsenoside Rg1
T2777
Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2
Target: Apoptosis, Beta Amyloid, NF-κB
Ginsenoside Rg2
T2873
Synonym: Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2
Target: Beta Amyloid, GSK-3, NF-κB
20(S)-Ginsenoside Rg3
T3402
Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Fustin
TN1653
Synonym:
Target: ERK, Beta Amyloid, AChR
Apicidin
T14305
Synonym: OSI 2040
Target: Apoptosis, HDAC, Autophagy

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00851 IDE Protein, Human, Recombinant (His) Human Human Cells
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a r...
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc) Human HEK293
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03884 Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03885 Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02110 Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02221 Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02393 Thimet Oligopeptidase/THOP1 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, high...
TMPY-00752 BACE1 Protein, Human, Recombinant (His) Human HEK293
Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells. In the brain, This protein is expressed highly in the substantia nigra, locus c...
TMPY-00651 BACE1 Protein, Human, Recombinant (hFc) Human HEK293
Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells. In the brain, This protein is expressed highly in the substantia nigra, locus c...
TMPY-00678 BACE1 Protein, Mouse, Recombinant (His) Mouse HEK293
Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells. In the brain, This protein is expressed highly in the substantia nigra, locus c...
TMPY-00652 BACE1 Protein, Human, Recombinant Human HEK293
Beta-site APP-cleaving enzyme 1 (BACE1) is an aspartic-acid protease important in the formation of myelin sheaths in peripheral nerve cells. In the brain, This protein is expressed highly in the substantia nigra, locus c...
TMPY-04555 GRK5 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRKs specifically ...
TargetMol