a-66

A66 is a specific and effective p110α inhibitor(IC50=32 nM).

4-Chlorothieno[3,2-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T7256 and the CAS number is 16269-66-2.

LL-37, Human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.

Compound Fr14015 is a useful organic compound for research related to life sciences. The catalog number is Fr14015 and the CAS number is 607-66-9.

4-Chlorophenylacetic acid is a useful organic compound for research related to life sciences. The catalog number is T65823 and the CAS number is 1878-66-6.

Ensartinib (X-396) is a potent dual ALK MET inhibitor with IC50 values of <0.4 nM for ALK and 0.74 nM for MET.

4',5-Dihydroxyflavone is a soybean LOX-1 inhibitor (Ki: 102.6 μM) and a yeast α-Glucosidase inhibitor (IC50: 66 μM).

WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).

UNC3866 is a potent antagonist of the CBX7-H3 interaction, as determined by AlphaScreen.

SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.

BRD0705 is a potent, orally active GSK3α inhibitor with high selectivity (IC50: 66 nM; Kd: 4.8 μM), demonstrating an 8-fold higher selectivity for GSK3α compared to GSK3β (IC50: 515 nM).

BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1 2.

CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).

Camphans?ure (+)- is a useful organic compound for research related to life sciences. The catalog number is T124427 and the CAS number is 67111-66-4.

(R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66938 and the CAS number is 331763-66-7.

Cyclocerberidol is a natural product for research related to life sciences. The catalog number is TN3739 and the CAS number is 126594-66-9.

Melengestrol acetate-d3 is a deuterated compound of Melengestrol acetate. Melengestrol acetate has a CAS number of 2919-66-6. Melengestrol acetate is a derivative of progesterone and acts as a corticosteroid hormone. Melengestrol acetate promotes endometrial proliferation delay of menstrual activity and pregnancy maintenance.

Dabigatran-d4 Hydrochloride is a deuterated compound of Dabigatran Hydrochloride. Dabigatran Hydrochloride has a CAS number of 1019206-66-6.

Deltatsine is a natural product of Delphinium, Ranunculaceae. The catalog number is TN6070 and the CAS number is 92631-66-8. Deltatsine can be used as a reference standard.

1,3-Diacetoxy-4,6,12-tetradecatriene-8,10-diyne is a useful organic compound for research related to life sciences. The catalog number is T125101 and the CAS number is 29576-66-7.

1,2-Diphenoxyethane is a useful organic compound for research related to life sciences. The catalog number is T67072 and the CAS number is 104-66-5.

Cyclofos-3 is a useful organic compound for research related to life sciences. The catalog number is TF0013 and the CAS number is 823796-66-3.

Ethylamine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65164 and the CAS number is 557-66-4.

4-Amino-3,5-dichlorobenzaldehyde is a useful organic compound for research related to life sciences. The catalog number is T66139 and the CAS number is 62909-66-4.

6-Hydroxy-3,4-dihydroquinolin-2(1H)-one is a useful organic compound for research related to life sciences. The catalog number is T67507 and the CAS number is 54197-66-9.

3,5-Dimethyl-4-nitropyridine 1-oxide is a useful organic compound for research related to life sciences. The catalog number is T67494 and the CAS number is 14248-66-9.

Antibacterial agent 66 (Compound 6q) is a trifluoromethylpyridine 1,3,4-oxadiazole derivative active against Xanthomonas oryzae pv. oryzae (Xoo) (EC50: 7.2 μg/mL).

Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. cervinatalarvae weight gain and food consumption. 1.Gallagher, R.T., Latch, G.C., and Keogh, R.G.The janthitrems: Fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pasturesAppl. Environ. Microbiol.39(1)272-273(1980) 2.Babu, J.V., Popay, A.J., Miles, C.O., et al.Identification and structure elucidation of janthitrems A and D from Penicillium janthinellum and determination of the tremorgenic and anti-insect activity of janthitrems A and BJ. Agric. Food Chem.66(50)13116-13125(2018)

Triethyl 2-phosphonopropionate is a useful organic compound for research related to life sciences. The catalog number is T65480 and the CAS number is 3699-66-9.

Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. It enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy [1].

Antitumor agent-66 (Compound 4) is a derivative of (-)-cleistenolide, exhibiting potential as a research tool for cancer diseases [1].

CDK6 9-IN-1 (compound 66) is a potent, orally administered dual inhibitor of CDK6 and CDK9, with IC50 values of 40.5 nM and 39.5 nM, respectively.

Anticancer agent 66, a ciprofloxacin analog, functions as an anti-cancer agent by inducing apoptosis and elevating the sub-G1 cell population in MCF-7 cells.

Hodgkinsine is a pyrrolidinoindoline alkaloid that has been found inP. colorataand has analgesic activity.1It increases latency to paw licking in the hot plate test and latency to tail withdrawal in the tail-flick test in mice when administered at a dose of 5 mg/kg. 1.Amador, T.A., Verotta, L., Nunes, D.S., et al.Antinociceptive profile of hodgkinsinePlanta Med.66(8)770-772(2000)

5,6,7-Trihydroxy-4'-methoxyflavone is a useful organic compound for research related to life sciences. The catalog number is T124460 and the CAS number is 6563-66-2.

2',4'-Dihydroxy-4-prenyloxychalcone is a useful organic compound for research related to life sciences. The catalog number is T126321 and the CAS number is 1158019-66-9.

Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity.

Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3).

PRL 3195 is a somatostatin receptor antagonist with K i values of 6, 17, 66, 1000, and 1000 nM for human somatostatin receptors sst 5, sst 2, sst 3, sst 1, and sst 4, respectively [1].

Syringolin B is a useful organic compound for research related to life sciences. The catalog number is T125254 and the CAS number is 235096-66-9.

3-(3,5-Dimethylphenoxy)propane-1,2-diol is a useful organic compound for research related to life sciences. The catalog number is T67469 and the CAS number is 59365-66-1.

Coumarsabin is a useful organic compound for research related to life sciences. The catalog number is T124179 and the CAS number is 81421-66-1.

DHP-218 is a calcium channel antagonist. DHP-218 inhibits Calcium-induced contraction of the rat aorta in high K+ solution with the pA2 value of 9.11. The IC50 value for the inhibitory effects of DHP-218 in high K+-induced and phenylephrine-induced contra

Durantoside II is a natural product of Duranta, Verbenaceae. The catalog number is TN3903 and the CAS number is 53526-66-2. Durantoside II can be used as a reference standard.

(1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone is a useful organic compound for research related to life sciences. The catalog number is T66245 and the CAS number is 895152-66-6.

2,4,5-Trifluoro-3-methoxybenzoyl chloride is a useful organic compound for research related to life sciences. The catalog number is T64937 and the CAS number is 112811-66-2.

ZLM-66 is a doravirine analogue and a potent inhibitor of non-nucleoside reverse transcriptases (NNRTIs), acting on wild-type HIV-1 reverse transcriptase (IC50: 41 nM), wild-type HIV-1 (EC50: 13 nM) and cIAP1 (EC50: 0.32 nM). ZLM-66 can be used in AIDS research.

VEGFR-2-IN-30, a compound acting primarily as a VEGFR-2 inhibitor (IC50: 66 nM), demonstrates additional inhibitory effects on PDGFR, EGFR, and FGFR1, with IC50 values of 180, 98, and 82 nM, respectively. It effectively arrests cancer cells in the S-phase and induces both early and late apoptosis.

Caryatin is a natural product for research related to life sciences. The catalog number is TN6239 and the CAS number is 1486-66-4.

alpha-Guanosine is a useful organic compound for research related to life sciences. The catalog number is TNU1639 and the CAS number is 15398-66-0.