caspase-3/7

Caspase-3/7 Activator 2 is a potent compound that selectively activates Caspase-3/7, demonstrating tumor specificity, anti-proliferative properties, and a high capacity for inducing apoptosis.

Caspase-3/7 Activator 3 is a potent and tumor-selective compound that effectively activates Caspase-3/7, demonstrating significant anti-proliferative activity and a high capacity to induce apoptosis.

3-Bromo-7-nitroindazole is a specific neuronal nitric oxide synthase (nNOS) inhibitor that affects the synthesis of the intercellular messenger NO throughout the brain and body.

(6Z)-7-Phenyl-7-(3-Pyridinyl)-6-Heptenoic Acid is a derivative of 7-Phenyl-7-(3-Pyridyl) -6-Heptenoic Acid that can be used in biological research.

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombophlebitis, atherosclerosis, cerebral embolism, stroke and pulmonary embolism.

3- Phenyl- N- [1- (phenylmethyl) - 4- piperidinyl] -tricyclo[3.3.1.13, 7] decane- 1- carboxamide with antiviral activity against Ebola virus that targets the surface-exposed glycoprotein and inhibits viral entry into host cells. In vitro studies in Vero cells revealed the compound inhibits the viral replication with EC50 of 0.38 μM.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.

Hemorphin-7 acetate is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE).

6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a compound used as a molecular structural unit for pefloxacin impurities.

3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one is a compound that has been extensively investigated for the treatment of a variety of disorders including tumors, Alzheimer's and Parkinson's diseases, anti-inflammatory drugs, and analgesic agents.

3',4',7-Trimethoxyquercetin (3,5-Dihydroxy-7,3',4'-trimethoxyflavone) is a polymethoxyquercetin isolated from Scutellaria baicalensis with antioxidant activity.

3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis.

3',4',7-Trimethoxyflavan is a natural product for research related to life sciences. The catalog number is T4240 and the CAS number is 116384-26-0.

3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclastogenesis via nuclear factor of activ

7-Amino-4-methylcoumarin-3-acetic acid [7-Amino-4-methylcoumarin] is a more suitable substrate for enteropeptidase compared to GD(4)K-NA.

MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a concentration-dependent manner.MMPSI can be used to study cardioprotection and myocardial injury.

Kaempferol 3-O-neohesperidoside 7-O-glucoside is a useful organic compound for research related to life sciences and the catalog number is T124218.

Stigmast-7-en-3-ol is a useful organic compound for research related to life sciences and the catalog number is T125511.

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T64879 and the CAS number is 162012-67-1.

1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66423 and the CAS number is 112811-57-1.

7-(4-Hydroxyphenyl)-5-methoxy-1-phenylheptan-3-one is a natural product for research related to life sciences. The catalog number is TN6372 and the CAS number is 100667-53-6.

1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66422 and the CAS number is 103460-89-5.

2-(4-Hydroxy-3-methoxyphenyl)-7-methoxy-5-benzofuranpropanol is a natural product for research related to life sciences. The catalog number is TN5407 and the CAS number is 144735-57-9.

7-Deaza-3’-deoxy-3’-fluoro-7-iodoadenosine is a useful organic compound for research related to life sciences and the catalog number is TNU0057.

3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64758.

1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane is a natural product for research related to life sciences. The catalog number is TN5758 and the CAS number is 182369-54-6.

3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride is a useful organic compound for research related to life sciences and the catalog number is T65076.

The compound 3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a cytotoxic tirucallane C26 triterpenoid that has been extracted from the stem barks of Aphanamixis grandifolia.

7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's disease (AD).

(R)-tert-Butyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate is a useful organic compound for research related to life sciences and the catalog number is T65597.

(3β,24S)-3-Hydroxystigmast-5-en-7-one (Compound 31), isolated from Lindera akoensis, exhibits anti-inflammatory activity [1].

2-Amino-3-(7-methyl-1H-indol-3-yl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T64952 and the CAS number is 17332-70-6.

7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) is a natural product for research related to life sciences. The catalog number is TN3217 and the CAS number is 79559-60-7.

Isorhamnetin 3-sophoroside-7-rhamnoside is a natural flavonol glycoside. Isorhamnetin 3-sophoroside-7-rhamnoside inhibited the growth of harmful microalgae. Isorhamnetin 3-sophoroside-7-rhamnoside is closely related to the convergence of different fruit pups, which is less affected by some known convergent compounds.

7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2',3'-dideoxynucleoside 5'-triphosphate that inhibits HIV-1 reverse transcriptase with a Ki of 25 nM [1].

Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha is a flavonol glycoside with no significant inhibitory effects on lipid accumulation induced by albumin oleate.

MMP-7-IN-3 is a potent and selective MMP-7 inhibitor that effectively suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction [1].

3-O-Methylquercetin 4',7-di-β-D-glucopyranoside, a flavonoside, is isolated from *Ophioglossum pedunculosum* [1].

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine is a useful organic compound for research related to life sciences. The catalog number is T66986 and the CAS number is 767340-03-4.

(R)-Methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate is a useful organic compound for research related to life sciences. The catalog number is T66656 and the CAS number is 10538-59-7.

Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and considerably diminishes post-traumatic apoptosis, enhancing neurological recovery in rats before and after traumatic brain injury induction.

7-Amino-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences and the catalog number is T67151.

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T67192 and the CAS number is 923036-30-0.

(R)-5-Hydroxy-7-(4-hydroxyphenyl)-1-phenylheptan-3-one is a natural product for research related to life sciences. The catalog number is TN6384 and the CAS number is 1961196-24-6.

1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione is a useful organic compound for research related to life sciences. The catalog number is T67692 and the CAS number is 764667-65-4.

5-Allyl-3-methoxy-6-methyl-7-(3,4,5-trimethoxyphenyl)bicyclo[3.2.1]oct-3-ene-2,8-dione is a natural product for research related to life sciences. The catalog number is TN3104 and the CAS number is 106894-43-3.

5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA) is a pancreatic lipase inhibitor, it shows antihyperlipidemic activity.