euphorbia

Deoxy euphorbia factor L1 is a natural product found in the seeds of Euphorbia lathyris L

Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr.

Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.

Euphorbia factor L9 is a useful organic compound for research related to life sciences and the catalog number is T126086.

Euphorbia factor L22 is a useful organic compound for research related to life sciences and the catalog number is T125686.

Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, anti-osteoclastogenic, and multidrug-resistant regulatory effects.

Euphorbia factor L25 is a useful organic compound for research related to life sciences and the catalog number is T125089.

Euphorbia factor L7a is a diterpene found in the seeds of Morinda citrifolia.

Euphorbia factor L8 is a diterpene from Morinda citrifolia seeds.

Euphorbia factor L24 is a useful organic compound for research related to life sciences and the catalog number is T125685.

Euphorbiasteroid (Euphobiasteroid) (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.

20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, antifungal and antioxidant effects.

1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability.

(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.t(E)-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.

1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance.

Phorbol 12-myristate 13-acetate (PMA), a member of the phorbol ester group of natural products, activates PKC, SphK, and NF-κB, and induces THP1 cell differentiation.

γ-L-Glutamyl-L-alanine consists of γ-glutamate and alanine, and is a substrate for CRF21 (γ-glutamyl cyclotransferase, GGCT), a proteolytic breakdown product of larger proteins.γ-L-Glutamyl-L-alanine is a positive regulator of calcium-sensitive receptor (CaR) function.

7β-Hydroxylathyrol is a diterpenoid extract from the seed oil of Caper Spurge and displays P-gp inhibition resulting in cytotoxic properties.

Maltol is a type of aromatic compound found in high concentrations in red ginseng and is a potent antioxidant used to enhance flavor and preserve food.

Kansuinine A possesses analgesic props, it also shows NGF inducing activity.

1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV. 3. Ingenol is a weak PKC activator and possesses important anticancer activity.

Ingenol-3,4,5,20-diacetonide, a natural product isolated from the sap of the Euphorbia plant, exhibits a wide range of biological activities, including anti-tumor, anti-inflammatory, and immunomodulatory effects.

Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM.

9-O-Ethyldeacetylorientalide is a natural product for research related to life sciences. The catalog number is TN3324 and the CAS number is 1258517-60-0.

(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell

Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphor

Germanicol acetate shows some slight cytotoxic activity against Jurkat cells .

Butyrospermol is a protolimonoid extracted from shea (Euphorbia). As a long-chain fatty acid ester first discovered from natural products, Butyrospermol has antifeedant and antitumor activities.

Ingenol 20-palmitate is a natural product from Euphorbia sieboldiana.

AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.

Euphorbadienol is a triterpenic compound isolated from the latex of Euphorbia resinifera. It has antileishmanial and antitrypanosomal activity.

ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide shows significant cytotoxic activity against ANA-1 and Jurkat cells with IC50 values 7.12 x 10(-3) and 1.79 x 10(-2) microM.

20-DEOXYINGENOL is a natual product.

Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration.

Euphoscopin C, a diterpenoid isolated from Euphorbia helioscopia, significantly enhances the cytotoxic activity of natural killer (NK) cells against H1299-luci and A549-luci cells [1].

Jatrophane VI is a natural product for research related to life sciences. The catalog number is TN4354 and the CAS number is 210108-90-0.

Gopherenediol shows weak antifeedant activity.

Pepluanin A, shows a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport.

5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane is a natural product for research related to life sciences. The catalog number is TN3097 and the CAS number is 210108-91-1.

Ebracteolata cpd B (TN3909, CAS 83459-37-4) is a natural product utilized in life sciences research.

Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.

Euphebracteolatin B, a natural product, can be isolated from the plant Euphorbia fischeriana [1].

20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets,

2',4'-Dihydroxy-3'-methoxyacetophenone is a natural product for research related to life sciences. The catalog number is TN2717 and the CAS number is 62615-26-3.

Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis.

Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity

3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN2890 and the CAS number is 244277-75-6. 3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one can be used as a reference standard.

5-hydroxythalidomide is a natural product for research related to life sciences. The catalog number is TN3098 and the CAS number is 219916-77-5.

Simiarenone is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN5025 and the CAS number is 2318-78-7. Simiarenone can be used as a reference standard.

Kaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan- 3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.