trans4,5epoxy2(e)decenal

Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of decomposed lipids, with a detection threshold of 1.5 pg/l in air.[1] trans-4,5-epoxy-2(E)-Decenal also reacts with nucleophiles (lysine amino groups) on proteins, leading to loss of cell function and viability.[2] This reactive aldehyde is therefore a useful tool in elucidating the effects of peroxidative damage in experimental models.

Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders The urinary excretion of Trans-2-butene-1,4-dicarboxylic acid is increased in conditions of augmented mobilization of fatty acids or inhibited fatty acid oxidation.

Trans-2-Hexenal (trans-2-Hexenal) is an α,β-unsaturated carbonyl compound protecting plants against harmful substances.

Methyl (E)-oct-2-enoate (Methyl trans-2-octenoate) is a volatile substance found in melons and fruits and is a flavor.

trans-2-Undecenoic acid ((E)-Undec-2-enoic acid) ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid characterized by acid dimers.

(E)-2-Methyl-2-pentenoic acid, characterized by its sweet berry-like aroma and flavor, is widely utilized in food flavoring.

(E)-2-Butenoic acid (Crotonic acid) is fatty acid formed by the action of fatty acid synthases from acetyl-CoA and malonyl-CoA precursors. Crotonic acid is involved in the fatty acid biosynthesis. Crotonic acid is also found in water extracts from carrot seeds (Daucus carota L.).

Ethyl (E)-dec-2-enoate (Ethyl trans-2-decenoate) is a fatty acid and a RIFM flavor.

(E)-Oct-2-enoic acid (2-Octenoate) is an organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally present in urine and plasma.

2-Ethylhexyl trans-4-methoxycinnamate is a sunscreen agent.

1H-Pyrrole-2-carboxylic acid, 4,5-dibromo-1-methyl- (1-methyl-4,5-dibromopyrrole-2-carboxylic acid) is a marine derived natural products found in Agelas flabelliformis.

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent.

Upenazime is a non-radioactive precursor agent for diagnostic imaging.

4,5-Dibromo-1H-Pyrrole-2-Carboxylic Acid (4,5-Dibromo-2-pyrrolic acid) is a marine derived natural products found in Agelas oroides.

2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv showed high local anti-inflammatory potency and high lung selectivity when tested on Sprague Dawley rats.

(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide is a cannabinoid receptor antagonist/inverse agonist.

（E)-1,7,7-trimethyl-3-（（3-（trifluoromethyl）phenyl）imino）bicyclo【2.2.1】heptan-2-one is a useful organic compound for research related to life sciences and the catalog number is T9539.

(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.

(E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees.

(E)-2-(2-Methylbut-2-enamido)acetic acid is a valuable organic compound for life sciences research (catalog number: T65378, CAS number: 35842-45-6).

Methyl 2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T67049 and the CAS number is 877997-99-4.

2-(5-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium is a useful organic compound for research related to life sciences and the catalog number is T64625.

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde (MDA) and decreases in superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities as well as increases constitutive nitric oxide synthase (cNOS) activity and nitric oxide (NO) production in HUVECs. CSTMP also induces cell death of A549 non-small cell lung cancer (NSCLC) cells in an IRE1α-dependent manner through induction of IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum (ER) stress and mitochondrial apoptosis.

(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. It is used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality. For in vitro applications, BMC may be used to facilitate protein refolding of solubilized proteins from inclusion bodies. Reducing agents, like dithiothreitol, may interfere with refolding. BMC may also be added to the growth medium of cells, including yeast cells, to enhance the folding of proteins with disulfide bonds in vivo.

(e)-3-(3,4-dihydroxyphenyl)-n-(2-(3,4-dihydroxyphenyl)ethyl)-2-propenamide is capable of interacting with proteins and other molecules in a variety of ways and has been used to study protein-protein interactions as well as enzyme-substrate interactions.

(E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences. The catalog number is T124254 and the CAS number is 765-01-5.

3-O-(2'E,4'E-decadienoyl)-20-O-acetylingenol is an important organic compound for life sciences research [Catalog No. T124827, CAS No. 466663-12-7].

2-Methylcinnamic acid, predominantly trans is a useful organic compound for research related to life sciences. The catalog number is T65873 and the CAS number is 2373-76-4.

(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is a useful organic compound for research related to life sciences. The catalog number is T66342 and the CAS number is 863127-76-8.

1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine is a natural product of Hernandia, Hernandiaceae. The catalog number is TN2479, and the CAS number is 872729-33-4. It can be used as a reference standard.

1-(2-Amino-4,5-dimethoxyphenyl)ethanone is a useful organic compound for research related to life sciences. The catalog number is T64852 and the CAS number is 4101-30-8.

(E)-3-(2-Chloro-4-fluorophenyl)acrylic acid is a useful organic compound for research related to life sciences. The catalog number is T67409 and the CAS number is 174603-37-3.

(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.

trans-2-Hexen-1-ol is a natural product for research related to life sciences. The catalog number is TN5162 and the CAS number is 928-95-0.

3-Cyanovinyl-9-(5’-O-(4,4’-dimethoxytrityl)-2’-deoxyribofuranosyl)carbazole (trans: CAS#1044273-26-8) is a useful organic compound for research related to life sciences and the catalog number is TNU0955.

Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6304 and the CAS number is 71781-79-8.

Butyl (E)-2-methylbut-2-enoate is an aromatic compound found in papaya.

(E)-dodec-2-en-1-ol (trans-2-Dodecen-1-ol) is a fatty aldehyde in coriander.

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide inhibits stress-induced ulcers by maintaining phospholipase A2 and prostaglandin E2 levels in rats subjected to water immersion-restrained stress-induced ulceration.

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol is a useful organic compound for research related to life sciences and the catalog number is T124424.

(E)-4-(4-Hydroxyphenyl)but-3-en-2-one is a useful organic compound for research related to life sciences and the catalog number is T125306.

Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate is a useful organic compound for research related to life sciences. The catalog number is T65341 and the CAS number is 144689-94-1.

8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol, a chemical component of essential oils from Telekia speciosa, exhibits significant antiproliferative activity against human cancer cell lines in vitro.

3-O-(2'E,4'Z-Decadienoyl)ingenol, catalog number T124104, is a valuable organic compound for life sciences research.

Methyl 2-(6-(1H-imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate is a useful organic compound for research related to life sciences and the catalog number is T64664.

(E)-Methyl 4-bromobut-2-enoate is a useful organic compound for research related to life sciences. The catalog number is T66096 and the CAS number is 6000-00-6.

(E)-2-(Hydroxyimino)-1-phenylpropan-1-one is a useful organic compound for research related to life sciences and the catalog number is T64528.

(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU), which can be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner, enhancing the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil in a P388 murine leukemia model when administered at a dose of 200 μmol kg, thereby increasing survival time.