T78677 |
LTB4 antagonist 2
|
2929239-85-8
|
98%
|
|
LTB4 antagonist 2, a carboxamide-acid compound, serves as an antagonist to leukotriene B4 (LTB4), possessing potential anti-inflammatory properties. It exhibits ...
|
T78678 |
LTB4 antagonist 3
|
2929239-87-0
|
98%
|
|
Compound 24e, a leukotriene B4 (LTB4) antagonist, exhibits an inhibitory concentration 50 (IC50) of 477 nM and demonstrates anti-inflammatory activity [1].
|
T79418 |
BLT2 antagonist-1
|
2069220-61-5
|
98%
|
|
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not affecti...
|
T72625 |
LTB4 antagonist 1
|
2929239-84-7
|
98%
|
|
LTB4 Antagonist 1, a carboxamide-acid derivative, potently inhibits Leukotriene B4 (LTB4) activity with an IC50 value of 288 nM and exhibits notable anti-inflamm...
|
T74212 |
BLT2 probe 1
|
2893803-05-7
|
98%
|
|
BLT2 Probe 1 (Compound 13), a fluorescent probe derived from the synthetic BLT2 agonist CAY10583, offers a robust tool for exploring BLT2 receptor ligand pharmac...
|
T0694 |
Pranlukast
|
103177-37-3
|
99.85%
|
|
Pranlukast (ONO-1078) is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic ...
|
TN1182 |
11-Keto-beta-boswellic acid
|
17019-92-0
|
99.7%
|
|
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifeste...
|
T68130 |
Pobilukast
|
107023-41-6
|
99.65%
|
|
Pobilukast (SKF 104353) is a selective cysteinyl leukotriene receptor antagonist that blocks phosphatidylinositol metabolism and leukotriene D-induced thromboxan...
|
T27979 |
Masilukast
|
136564-68-6
|
99.53%
|
|
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation.
|
T22946 |
LY255283
|
117690-79-6
|
99.45%
|
|
LY255283 is a specific antagonit of leukotriene B4 (LTB4) receptor. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (...
|
T1677L |
Montelukast sodium
|
151767-02-1
|
99.35%
|
|
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and h...
|
T12771 |
RS-601
|
207987-59-5
|
99.31%
|
|
RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in a g...
|
T24327 |
L 674573
|
127481-29-2
|
99.22%
|
|
L 674573 is an inhibitor of leukotriene biosynthesis.
|
T26519 |
Ablukast
|
96566-25-5
|
99.18%
|
|
Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.
|
T22358 |
Etalocib
|
161172-51-6
|
98.92%
|
|
Etalocib (LY293111) is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of ...
|
T30828 |
CGP 35949
|
111130-13-3
|
98.89%
|
|
CGP 35949 is an LTD4 antagonist with phospholipase inhibitory activity.
|
T3148 |
MK-571 sodium
|
115103-85-0
|
98.69%
|
|
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, M...
|
T23390 |
SR 2640 hydrochloride
|
146662-42-2
|
98.36%
|
|
SR 2640 hydrochloride is a competitive antagonist of leukotriene D4 and E4 and can be used in studies about leukotrienes in human asthma.
|
T14387 |
AZD9898
|
2042347-69-1
|
98.27%
|
|
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and...
|
T26524 |
ABT-080
|
189498-57-5
|
98.15%
|
|
ABT-080 (VML 530), a leukotriene synthesis inhibitor, is used potentially for treatment of asthma.
|