T6412 |
CVT-12012
|
1018675-35-8
|
98%
|
|
CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).
|
T16068 |
MF-438
|
921605-87-0
|
98%
|
|
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
|
T1869 |
PluriSIn 1
|
91396-88-2
|
98%
|
|
PluriSln 1(NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism ...
|
T14878 |
CAY10566
|
944808-88-2
|
98%
|
|
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 c...
|
T13356 |
XEN723
|
1072803-08-7
|
98%
|
|
XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
|
T5427 |
GSK1940029
|
1150701-66-8
|
98%
|
|
GSK1940029 is a stearoyl-coa desaturase (SCD) inhibitor.
|
T10525 |
SCD1 inhibitor-4
|
1295541-87-5
|
98%
|
|
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
|
T4515 |
A939572
|
1032229-33-6
|
98%
|
|
A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.
|
T3341 |
Elemicin
|
487-11-6
|
98%
|
|
Elemicin is a constituent of several plant species' essential oils with anticholinergic effects in human.
|
T9722 |
YTX-465
|
2225824-53-1
|
98%
|
|
YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM).
|
T2650 |
MK-8245
|
1030612-90-8
|
98%
|
|
MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.
|
T12931 |
SLC13A5-IN-1
|
2227548-95-8
|
98%
|
|
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).
|