a 66

A66 is a specific and effective p110α inhibitor(IC50=32 nM).

Antibacterial agent 66 (Compound 6q) is a trifluoromethylpyridine 1,3,4-oxadiazole derivative active against Xanthomonas oryzae pv. oryzae (Xoo) (EC50: 7.2 μg/mL).

Antitumor agent-66 (Compound 4) is a derivative of (-)-cleistenolide, exhibiting potential as a research tool for cancer diseases [1].

Anticancer agent 66, a ciprofloxacin analog, functions as an anti-cancer agent by inducing apoptosis and elevating the sub-G1 cell population in MCF-7 cells.

ZLM-66 is a doravirine analogue and a potent inhibitor of non-nucleoside reverse transcriptases (NNRTIs), acting on wild-type HIV-1 reverse transcriptase (IC50: 41 nM), wild-type HIV-1 (EC50: 13 nM) and cIAP1 (EC50: 0.32 nM). ZLM-66 can be used in AIDS research.

SARS-CoV-2-IN-66 (1), a derivative of vitamin K, serves as an inhibitor of SARS-CoV-2, with an effective concentration (EC50) of 70.8 μM in VeroE6 TMPRSS2 cells [1].

Compound 578-66-5 is a useful organic compound for research related to life sciences. The catalog number is TPL0185 and the CAS number is 578-66-5.

HSD17B13-IN-66 (Compound 146), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), shows a potent IC 50 value of ≤ 0.1 μM for estradiol. This compound is primarily utilized in research pertaining to liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells.

Antifungal agent 66 (compound 10) demonstrates broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and provides significant inhibitory effects on the spores of B. cinerea, with an IC50 value of 47.7 μg mL [1].

LL-37, Human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.

5-TAMRA can produce bright, pH insensitive orange fluorescence (Ex/ Em= 546 / 579nm), and has good photostability

Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease.

SC66 is a AKT inhibitor in HepG2, HA22T VGH, and PLC PRF 5 cells (IC50: about 0.75 μg ml, at 72 h).

CEF1, Influenza Matrix Protein M1 (58-66), is an epitope derived from the matrix protein of the influenza A virus. GILGFVFTL is an HLA-A2-restricted epitope from this matrix M1 protein.

BAK2-66 is a selective antagonist of the dopamine D3 receptor.

W 67 is a biochemical.

Human LL-37 is a 37 amino acid cationic (6+) peptide and has been widely studied. LL-37 penetrates the bacterial membrane and forms pores in the membrane.

PD-1-IN-17 TFA is a inhibitor of programmed cell death-1 (PD-1) .

CH 66 is an inhibitor of renin.

4-Chlorothieno[3,2-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T7256 and the CAS number is 16269-66-2.

Compound Fr14015 is a useful organic compound for research related to life sciences. The catalog number is Fr14015 and the CAS number is 607-66-9.

4-Chlorophenylacetic acid is a useful organic compound for research related to life sciences. The catalog number is T65823 and the CAS number is 1878-66-6.

Ensartinib (X-396) is a potent dual ALK MET inhibitor with IC50 values of <0.4 nM for ALK and 0.74 nM for MET.

4',5-Dihydroxyflavone is a soybean LOX-1 inhibitor (Ki: 102.6 μM) and a yeast α-Glucosidase inhibitor (IC50: 66 μM).

WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).

UNC3866 is a potent antagonist of the CBX7-H3 interaction, as determined by AlphaScreen.

SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.

BRD0705 is a potent, orally active GSK3α inhibitor with high selectivity (IC50: 66 nM; Kd: 4.8 μM), demonstrating an 8-fold higher selectivity for GSK3α compared to GSK3β (IC50: 515 nM).

BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1 2.

CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).

Camphans?ure (+)- is a useful organic compound for research related to life sciences. The catalog number is T124427 and the CAS number is 67111-66-4.

(R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66938 and the CAS number is 331763-66-7.

Cyclocerberidol is a natural product for research related to life sciences. The catalog number is TN3739 and the CAS number is 126594-66-9.

Melengestrol acetate-d3 is a deuterated compound of Melengestrol acetate. Melengestrol acetate has a CAS number of 2919-66-6. Melengestrol acetate is a derivative of progesterone and acts as a corticosteroid hormone. Melengestrol acetate promotes endometrial proliferation delay of menstrual activity and pregnancy maintenance.

Dabigatran-d4 Hydrochloride is a deuterated compound of Dabigatran Hydrochloride. Dabigatran Hydrochloride has a CAS number of 1019206-66-6.

Deltatsine is a natural product of Delphinium, Ranunculaceae. The catalog number is TN6070 and the CAS number is 92631-66-8. Deltatsine can be used as a reference standard.

1,3-Diacetoxy-4,6,12-tetradecatriene-8,10-diyne is a useful organic compound for research related to life sciences. The catalog number is T125101 and the CAS number is 29576-66-7.

1,2-Diphenoxyethane is a useful organic compound for research related to life sciences. The catalog number is T67072 and the CAS number is 104-66-5.

Cyclofos-3 is a useful organic compound for research related to life sciences. The catalog number is TF0013 and the CAS number is 823796-66-3.

Ethylamine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65164 and the CAS number is 557-66-4.

4-Amino-3,5-dichlorobenzaldehyde is a useful organic compound for research related to life sciences. The catalog number is T66139 and the CAS number is 62909-66-4.

6-Hydroxy-3,4-dihydroquinolin-2(1H)-one is a useful organic compound for research related to life sciences. The catalog number is T67507 and the CAS number is 54197-66-9.

3,5-Dimethyl-4-nitropyridine 1-oxide is a useful organic compound for research related to life sciences. The catalog number is T67494 and the CAS number is 14248-66-9.

Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. cervinatalarvae weight gain and food consumption. 1.Gallagher, R.T., Latch, G.C., and Keogh, R.G.The janthitrems: Fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pasturesAppl. Environ. Microbiol.39(1)272-273(1980) 2.Babu, J.V., Popay, A.J., Miles, C.O., et al.Identification and structure elucidation of janthitrems A and D from Penicillium janthinellum and determination of the tremorgenic and anti-insect activity of janthitrems A and BJ. Agric. Food Chem.66(50)13116-13125(2018)

Triethyl 2-phosphonopropionate is a useful organic compound for research related to life sciences. The catalog number is T65480 and the CAS number is 3699-66-9.

Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. It enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy [1].

CDK6 9-IN-1 (compound 66) is a potent, orally administered dual inhibitor of CDK6 and CDK9, with IC50 values of 40.5 nM and 39.5 nM, respectively.

Hodgkinsine is a pyrrolidinoindoline alkaloid that has been found inP. colorataand has analgesic activity.1It increases latency to paw licking in the hot plate test and latency to tail withdrawal in the tail-flick test in mice when administered at a dose of 5 mg/kg. 1.Amador, T.A., Verotta, L., Nunes, D.S., et al.Antinociceptive profile of hodgkinsinePlanta Med.66(8)770-772(2000)

5,6,7-Trihydroxy-4'-methoxyflavone is a useful organic compound for research related to life sciences. The catalog number is T124460 and the CAS number is 6563-66-2.