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Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Tanshinone IIA sulfonate sodium (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats.

Aescin IIA is a natural product

1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2 STAT3.

Virginiamycin M1 (Pristinamycin IIA) is a macrocyclic lactone peptide antibiotic and is a member of the streptogramin A group of antibiotics.

Hemslecin D is a natural product for research related to life sciences. The catalog number is TN5989 and the CAS number is 586960-44-3.

Tanshinone IIA (Tanshinone B) is a diterpene quinone natural product that targets the protein kinase domain of VEGF VEGFR2. Tanshinone IIA inhibits angiogenesis and exhibits anti-inflammatory, antioxidant, and therapeutic activities against coronary heart disease.

11-Oxomogroside IIa is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. It has inhibitory effects against the EBV-EA activation induced by TPA, shows weak inhibitory effects on activation of NOR 1, a nitric oxide (NO) donor.

Tanshinone IIA anhydride is a potent, irreversible inhibitor of human carboxylesterase (CE), exhibiting inhibitory constants (K i values) of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE), respectively [1].

1,2-Didehydrotanshinone IIA is a useful organic compound for research related to life sciences and the catalog number is T126245.

Hydroxytanshinone ⅡA has good antiproliferative effect on SGC-7901,HeLa, and HepG 2 cell, the values of IC50 are 4.18, 6.08 and10.20 uM, respectively; it has tumor cell proliferation inhibition significantly stronger than the tanshinoneⅡA.

Cucurbitacin IIa 2-O-glucoside is a natural product for research related to life sciences. The catalog number is TN5995 and the CAS number is 77704-34-8.

3α-Hydroxytanshinone IIA (Compound 5), an isolatable compound from the roots of Salvia miltiorrhiza [1], exhibits specific characteristics.

3alpha-Hydroxytanshinone IIA is a useful organic compound for research related to life sciences and the catalog number is T123833.

Momordin IIa is a useful organic compound for research related to life sciences and the catalog number is T123849.

Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite.

Sulfotanshinone IIA Sodium mitigates oxidative damage in peritoneal mesothelial cells caused by peritoneal dialysis solution (PDS) by inhibiting the ASK1-p38 signaling pathway.

Cinchonain IIa has antioxidant activity, it shows high radical scavenging activity and reducing power.

1-Oxotanshinone IIA (Compound 6), derived from Perovskia artemisioides, exhibits potent anti-inflammatory activity [1].

11-Oxomogroside IIA2 is a natural product for research related to life sciences. The catalog number is TN6624 and the CAS number is 2170761-37-0.

Mogroside IIA1 (Mogroside II-A1) is isolated from the fruits of Siraitia grosvenorii. Mogroside IIA1 is a a nonsugar sweetener and sweeter than sucrose. Mogroside IIA1 possesses antioxidant, antidiabetic and anticancer activities.

Aristololactam IIIa demonstrates substantial inhibition of superoxide anion generation and elastase release, exhibiting IC50 values of 0.12 and 0.20 μg/mL, respectively [1].

Atractysucrose IIIa is a useful organic compound for research related to life sciences. The catalog number is T126467 and the CAS number is 1053636-75-1.

Aristolactam IIIa N-β-glucoside is a natural product for research related to life sciences. The catalog number is TN6118 and the CAS number is 80311-26-8.

Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB signaling.

Aristolactam AIIIa is a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD), it has anti-tumor activity. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid.

Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.