ppa

PPA serves as an ADC linker (US20060073528A1), facilitating the production of antibody-drug conjugates.

PPA-904 FA is a cationic photosensitizer with broad-spectrum antimicrobial activity for use in photodynamic studies (PDT) studies, which can be used to study chronic leg ulcers and diabetic foot ulcers.

PPA-904 is a selective phenothiazine photosensitizer with potential antitumor activity for the study of diabetic foot ulcers and chronic leg ulcers.

2',3'-cGAMP-C2-PPA (45) is a cyclic di-nucleotide that acts as a STING agonist (US20210015941A1). It is a drug-linker conjugate for antibody-drug conjugates (ADC) used in the targeted treatment of cancer.

PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.

(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an affinity for PD-1 of 0.51 μM and demonstrating efficacy both in vitro and in vivo [1].

Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids.

MTPPA (M 5011) is treating inflammation and pain.

Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.

Pyropheophorbide-a (Ppa) shows promise as a photosensitizer in tumor photodynamic therapy (PDT).

2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE is targets the thyroid stimulating hormone receptor (human)

1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, via activation of a MDM2-dependent ubiquitination process.

Mouse IgG3 kappa Isotype Control is a monoclonal antibody serving as an isotype control specifically for mouse IgG3κ antibodies.

Human IgG1 (D265A) kappa Isotype Control is a chimeric monoclonal antibody derived from both human and mouse, designed to serve as an isotype control for the human IgG1 (D265A)κ antibody.

PPACK is a synthetic peptide derivative. It also irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM).

Sappanol is a useful organic compound for research related to life sciences and the catalog number is T126391.

pppApG serves as an initial substrate for the synthesis of vRNA (viral RNA) and cRNA (complementary RNA), with applications in influenza virus research [1].

Human IgG1 (S239D/I332E) kappa Isotype Control is a chimeric monoclonal antibody derived from human and mouse sequences, serving as an isotype control for the Human IgG1 (S239D/I332E)κ antibody.

Human IgG1 (D270N) kappa Isotype Control is a chimeric human-mouse monoclonal antibody that serves as an isotype control for the human IgG1 (D270N)κ antibody.

Human IgG3 kappa Isotype Control is a chimeric monoclonal antibody comprising human and mouse components, serving as an isotype control for human IgG3κ antibodies.

Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an

Lappaol B is a natural product for research related to life sciences. The catalog number is TN6463 and the CAS number is 62359-60-8.

4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana.

Rabbit IgG1 kappa Isotype Control is a rabbit monoclonal antibody serving as an isotype control for Rabbit IgG1κ antibody.

Mouse IgG2c kappa Isotype Control is a monoclonal antibody serving as a specificity control for mouse IgG2cκ antibody assays.

Mouse IgG2b kappa Isotype Control is a mouse monoclonal antibody serving as an isotype control for mouse IgG2bκ antibody applications.

3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings.

Hippadine is isolated from Crinum bulbs and has reproductive effect.

Mouse IgG1 kappa Isotype Control is a mouse monoclonal antibody that serves as an isotype control for mouse IgG1κ antibodies.

Mouse IgG1 (D265A) kappa Isotype Control is a monoclonal antibody that serves as an isotype control for Mouse IgG1 (D265A) κ antibody.

Human IgG1 (K214R) kappa Isotype Control is a chimeric monoclonal antibody that serves as an isotype control for the human IgG1 (K214R)κ antibody.

m7GpppAmpG ammonium is a trinucleotide 5′ cap analog that exhibits capping efficiencies of 90% for the RNAs obtained [1].

PPACK Dihydrochloride is the dihydrochloride form of its active component PPACK (D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone), a potent, selective, and irreversible inhibitor of thrombin that inhibits human α-thrombin with inhibition constant (

1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade.
2. Lappaol F has potential chemosensitizing activity, it may be candidates for developing novel adju

Isolappaol C is a natural product for research related to life sciences. The catalog number is TN6462 and the CAS number is 929905-15-7.

Mouse IgG2a (D265A) kappa Isotype Control is a monoclonal antibody serving as an isotype control specifically for the Mouse IgG2a (D265A) antibody.

Mouse IgG1 kappa (N297A) Isotype Control is a mouse monoclonal antibody serving as an isotype control specifically for Mouse IgG1(N297A)κ antibodies.

10-O-Methylprotosappanin B is a protosaponin analog present in Haematococcus brasiliensis collected from northern Colombia.

Human IgG4 kappa Isotype Control is a monoclonal antibody serving as an isotype control for the human IgG4κ antibody [1].

PPARα-MO-1 is a potent modulator of PPARα.

APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of the polyol pathway. This compound shows promise for research into diabetic nephropathy (DN) [1].

Isolappaol A is a natural product for research related to life sciences. The catalog number is TN6461 and the CAS number is 131400-96-9.

3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.

Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.

Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.

vanilloid TRPV1 (VR1) receptor agonist

PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ. This compound does not exhibit cytotoxicity towards both non-resistant and resistant cells. Notably, PPARγ agonist 3 demonstrates antitumor efficacy exclusively when co-administered with Imatinib [1].

PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects. pparγ agonist 1 has shown research potential in cardiovascular diseases associated with metabolic disorders.

3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4.

Sappanone B is a useful organic compound for research related to life sciences and the catalog number is T126481.