Factor Xa

Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.Factor X is activated, by hydrolysis, into factor Xa by both factor IX (with its cofactor, factor VIII in a complex known as intrinsic Tenase) and factor VII with its cofactor, tissue factor (a complex known as extrinsic Tenase ). It is therefore the first member of the final common pathway or thrombin pathway.

Cat. No.	Product name	CAS No.	Purity
T19488	O-Desmethyl apixaban sulfate sodium	T19488	98%
T19488	O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
T12736	Rivaroxaban-d4	1132681-38-9	98%
T12736	Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
T12782	RWJ-445167	226566-43-4	98%
T12782	RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.
T6531	Heparin sodium salt	9041-08-1
T6531	Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse p...
T4076	Fondaparinux sodium	114870-03-0	98%
T4076	Fondaparinux Sodium is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
T10174	5-R-Rivaroxaban	865479-71-6	98.3%
T10174	5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0...
T20454	4-Chlorophenylurea	140-38-5	98.69%
T20454	4-Chlorophenylurea is a novel orally bioavailable inhibitor of factor Xa.
T31206	Darexaban	365462-23-3	98.81%
T31206	Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothr...
T4341	Betrixaban	330942-05-7	99.35%
T4341	Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
T4690	Betrixaban hydrochloride(330942-05-7(free base))	T4690	99.54%
T4690	Betrixaban is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
T0642	2-Methoxyphenothiazine	1771-18-2	99.56%
T0642	2-Methoxy Phenothiazine is light yellow or light gray solid.
T2368L	Edoxaban	480449-70-5	99.6%
T2368L	Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respecti...
T0372	Gabexate mesylate	56974-61-9	99.64%
T0372	Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a ...
T1184	Rivaroxaban	366789-02-8	99.69%
T1184	Rivaroxaban is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administr...
T1736	Apixaban	503612-47-3	99.7%
T1736	Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the c...
T0775	Coumarin	91-64-5	99.96%
T0775	Coumarin is a chemical compound/poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as...
T2368	Edoxaban Tosylate Monohydrate	1229194-11-9	99.97%
T2368	Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
T4980	Betrixaban maleate	936539-80-9	99.46%
T4980	Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...