T34648 |
Sinitrodil
|
143248-63-9
|
98%
|
|
Sinitrodil is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
|
T6968 |
Riociguat
|
625115-55-1
|
98%
|
|
Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
|
T1984 |
Cinaciguat
|
329773-35-5
|
98%
|
|
Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failur...
|
T17226 |
Vericiguat
|
1350653-20-1
|
98%
|
|
Vericiguat is a potent and orally available guanylate cyclase stimulator.
|
T21607 |
Ataciguat
|
254877-67-3
|
98%
|
|
Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
|
T67734 |
MCUF-651
|
2747162-85-0
|
98%
|
|
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
|
T21712 |
BAY 41-8543
|
256498-66-5
|
98%
|
|
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
|
T4381 |
Lificiguat
|
170632-47-0
|
98%
|
|
YC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
|
T16344 |
NS-2028
|
204326-43-2
|
98%
|
|
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used ...
|
T16383 |
Olinciguat
|
1628732-62-6
|
98%
|
|
Olinciguat is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a wh...
|
T7201 |
Nelociguat
|
625115-52-8
|
98%
|
|
Nelociguat(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signa...
|
T16569 |
Praliciguat
|
1628730-49-3
|
98%
|
|
Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances ...
|
T21576 |
LY83583
|
91300-60-6
|
98%
|
|
LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.
|
T19777 |
ODQ
|
41443-28-1
|
98%
|
|
ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.
|
T11852 |
Linaclotide
|
851199-59-2
|
98%
|
|
Linaclotide developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, and is a potent and selective guan...
|
T0006 |
Methylene Blue trihydrate
|
7220-79-3
|
98%
|
|
Methylene blue is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue...
|
T9080 |
Plecanatide
|
467426-54-6
|
98%
|
|
Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.
|
T6991 |
Nitroprusside disodium dihydrate
|
13755-38-9
|
98%
|
|
Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.
|
T16808 |
Runcaciguat
|
1402936-61-1
|
98%
|
|
Runcaciguat is a soluble guanylate cyclase stimulator. Runcaciguat combines with selective partial adenosine A1 receptor agonists and can be used in studies abou...
|
T6888 |
Methylene Blue
|
61-73-4
|
98%
|
|
Methylene Blue(IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
|