T80067 |
Uroguanylin (human)
|
154525-25-4
|
98%
|
|
Uroguanylin (human) serves as a natural ligand for the Guanylyl Cyclase C (GCC) receptor in metastatic colorectal cancer tumors and exhibits anti-tumor effects i...
|
T80150 |
Guanylin (mouse, rat)
|
145257-03-0
|
98%
|
|
Guanylin (mouse, rat), a peptide consisting of 15 amino acids, acts as an activator of intestinal guanylate cyclase and is utilized in diarrhea research [1].
|
T6968 |
Riociguat
|
625115-55-1
|
99.91%
|
|
Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hype...
|
T17226 |
Vericiguat
|
1350653-20-1
|
99.6%
|
|
Vericiguat (BAY1021189) is a potent and orally available guanylate cyclase stimulator.
|
T21607 |
Ataciguat
|
254877-67-3
|
99.57%
|
|
Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
|
T67734 |
MCUF-651
|
2747162-85-0
|
99.57%
|
|
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
|
T21712 |
BAY 41-8543
|
256498-66-5
|
99.49%
|
|
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
|
T16344 |
NS-2028
|
204326-43-2
|
99.44%
|
|
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used ...
|
T16383 |
Olinciguat
|
1628732-62-6
|
99.33%
|
|
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assay...
|
T7201 |
Nelociguat
|
625115-52-8
|
99.15%
|
|
Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxi...
|
T16569 |
Praliciguat
|
1628730-49-3
|
99.05%
|
|
Praliciguat (IW-1973) stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also...
|
T34648 |
Sinitrodil
|
143248-63-9
|
99%
|
|
Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
|
T21576 |
LY83583
|
91300-60-6
|
98.71%
|
|
LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.
|
T19777 |
ODQ
|
41443-28-1
|
98.46%
|
|
ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.
|
T11852 |
Linaclotide
|
851199-59-2
|
97.93%
|
|
Linaclotide developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, and is a potent and selective guan...
|
T9080 |
Plecanatide
|
467426-54-6
|
97.51%
|
|
Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.
|
T11424 |
Glutaminyl Cyclase Inhibitor 1
|
2110449-60-8
|
100%
|
|
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.
|
T6991 |
Nitroprusside disodium dihydrate
|
13755-38-9
|
|
|
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
|
T0006 |
Methylene Blue trihydrate
|
7220-79-3
|
98%
|
|
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water o...
|
T16808 |
Runcaciguat
|
1402936-61-1
|
98%
|
|
Runcaciguat is a soluble guanylate cyclase stimulator. Runcaciguat combines with selective partial adenosine A1 receptor agonists and can be used in studies abou...
|