T11886 |
LTβR-IN-1
|
2189366-77-4
|
98%
|
|
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12...
|
T15002 |
CP-105696
|
158081-99-3
|
98%
|
|
CP-105696 is a selective antagonist of Leukotriene B4 Receptor (IC50: 8.42 nM).
|
T17191 |
Bunaprolast
|
99107-52-5
|
98%
|
|
Bunaprolast shows significant inhibition of lipoxygenase and TXB2 release. Bunaprolast is a potent inhibitor of LTB4 production in human whole blood.
|
T11487L |
Fiboflapon sodium
|
1196070-26-4
|
98%
|
|
Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of ...
|
T15182 |
DW-1350
|
491577-61-8
|
98%
|
|
DW-1350 is an antagonist of LTB4 receptor.
|
T14210 |
Amelubant
|
346735-24-8
|
98%
|
|
Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long act...
|
T15813 |
LY309887
|
127228-54-0
|
98%
|
|
LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.
|
TN5164 |
Trans-Hinokiresinol
|
17676-24-3
|
98%
|
|
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
|
T11487 |
Fiboflapon
|
936350-00-4
|
98%
|
|
Fiboflapon is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition...
|
T16395 |
ONO4057
|
134578-96-4
|
98%
|
|
ONO4057 is an antagonist of the Leukotriene B4 receptor (IC50: 0.7±0.3 μM).
|
TN3983 |
Ergosta-7,22-dien-3-one
|
32507-77-0
|
98%
|
|
Ergosta-7,22-dien-3-one shows pro-inflammatory property, it can stimulate nitric oxide production, induce the expression of genes, and induce the production of T...
|
T10208 |
A-69412
|
123606-23-5
|
98%
|
|
A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other in...
|
T13295 |
Veliflapon
|
128253-31-6
|
98%
|
|
Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP). Veliflapon inhibits the synthesis of the leukotrienes B4 and ...
|
T9878 |
Croconazole
|
77175-51-0
|
98%
|
|
Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils. Croconazole is an antimycotic agent. The IC50s for the syn...
|
T10960 |
Darbufelone
|
139226-28-1
|
98%
|
|
Darbufelone is a non-competitive dual inhibitor of PGF2α and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGH...
|
T21504 |
γ-Linolenic Acid methyl ester
|
16326-32-2
|
|
|
γ-Linolenic Acid methyl ester is a weak leukotriene B4 (LTB4) receptor antagonist.
|
T1677 |
Montelukast
|
158966-92-8
|
100%
|
|
Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked t...
|
T3738 |
3-(4-Hydroxyphenyl)-1-propanol
|
10210-17-0
|
98.38%
|
|
3-(4-hydroxyphenyl)-1-propanol is a member of the class of compounds known as 1-hydroxy-2-unsubstituted benzenoids.
|
T3148 |
MK-571 sodium
|
115103-85-0
|
98.69%
|
|
MK-571 is a selective, orally active antagonist of the CysLT1 receptor. MK571 is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the...
|
T22358 |
Etalocib
|
161172-51-6
|
98.92%
|
|
Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotr...
|