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LTR

LTR retrotransposons are class I transposable element characterized by the presence of Long Terminal Repeats (LTRs) directly flanking an internal coding region. As retrotransposons, they mobilize through reverse-transcription of their mRNA and integration of the newly created cDNA into another location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that most LTR-retrotransposons do not form infectious particles that leave the cells and therefore only replicate inside their genome of origin.
Cat No. product name
T3148 MK-571 sodium MK-571 is a selective, orally active antagonist of the CysLT1 receptor. MK571 is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the...
T1677 Montelukast Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked t...
T22358 Etalocib Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotr...
T0694 Pranlukast Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to...
T1257 Bestatin Ubenimex competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential...
T4114 Diffractaic Acid Diffractaic Acid can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.
T1677L Montelukast sodium Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked t...
T3715 Acebilustat Acebilustat (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.
T21504 γ-Linolenic Acid methyl ester γ-Linolenic Acid methyl ester is a weak leukotriene B4 (LTB4) receptor antagonist.
T7841 MK 571 MK 571 is an orally active antagonist of CysLT1 receptor .
T13295 Veliflapon Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP). Veliflapon inhibits the synthesis of the leukotrienes B4 and ...
T10208 A-69412 A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other in...
T10917 LTB4-IN-1 LTB4-IN-1 with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4).
T11487L Fiboflapon sodium Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of ...
T11487 Fiboflapon Fiboflapon is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition...
TN3983 Ergosta-7,22-dien-3-one Ergosta-7,22-dien-3-one shows pro-inflammatory property, it can stimulate nitric oxide production, induce the expression of genes, and induce the production of T...
TN5164 Trans-Hinokiresinol Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
T4192 Hnps-PLA Inhibitor Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
T3738 3-(4-Hydroxyphenyl)-1-propanol 3-(4-hydroxyphenyl)-1-propanol is a member of the class of compounds known as 1-hydroxy-2-unsubstituted benzenoids.
T15182 DW-1350 DW-1350 is an antagonist of LTB4 receptor.
T15002 CP-105696 CP-105696 is a selective antagonist of Leukotriene B4 Receptor (IC50: 8.42 nM).
T14210 Amelubant Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long act...
T17191 Bunaprolast Bunaprolast shows significant inhibition of lipoxygenase and TXB2 release. Bunaprolast is a potent inhibitor of LTB4 production in human whole blood.
T15815 LY3295668 LY3295668 is an effective and orally active and highly specific inhibitor of Aurora-A kinase (Ki: 0.8 nM and 1038 nM for AurA and AurB, respectively).
T15813 LY309887 LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.
T16395 ONO4057 ONO4057 is an antagonist of the Leukotriene B4 receptor (IC50: 0.7±0.3 μM).
T9878 CROCONAZOLE Croconazole 对中性粒细胞的 5-脂氧合酶 (5-LOX) 表现出剂量依赖性抑制活性。Croconazole 是一种抗真菌剂。Croconazole 对合成白三烯 B4 (LTB4) 和 5-羟基二十碳四烯酸 (5-HETE) 的 IC50 分别为 7.8 ± 1.7 和 7.6 ± 0.3 μM。
MK-571 sodium
T3148
MK-571 is a selective, orally active antagonist of the CysLT1 receptor. MK571 is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the...
Montelukast
T1677
Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked t...
Etalocib
T22358
Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotr...
Pranlukast
T0694
Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to...
Bestatin
T1257
Ubenimex competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential...
Diffractaic Acid
T4114
Diffractaic Acid can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.
Montelukast sodium
T1677L
Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked t...
Acebilustat
T3715
Acebilustat (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.
γ-Linolenic Acid methyl ester
T21504
γ-Linolenic Acid methyl ester is a weak leukotriene B4 (LTB4) receptor antagonist.
MK 571
T7841
MK 571 is an orally active antagonist of CysLT1 receptor .
Veliflapon
T13295
Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP). Veliflapon inhibits the synthesis of the leukotrienes B4 and ...
A-69412
T10208
A-69412 is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other in...
LTB4-IN-1
T10917
LTB4-IN-1 with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4).
Fiboflapon sodium
T11487L
Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of ...
Fiboflapon
T11487
Fiboflapon is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition...
Ergosta-7,22-dien-3-one
TN3983
Ergosta-7,22-dien-3-one shows pro-inflammatory property, it can stimulate nitric oxide production, induce the expression of genes, and induce the production of T...
trans-Hinokiresinol
TN5164
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
hnps-PLA Inhibitor
T4192
Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
3-(4-Hydroxyphenyl)-1-propanol
T3738
3-(4-hydroxyphenyl)-1-propanol is a member of the class of compounds known as 1-hydroxy-2-unsubstituted benzenoids.
DW-1350
T15182
DW-1350 is an antagonist of LTB4 receptor.
CP-105696
T15002
CP-105696 is a selective antagonist of Leukotriene B4 Receptor (IC50: 8.42 nM).
Amelubant
T14210
Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long act...
Bunaprolast
T17191
Bunaprolast shows significant inhibition of lipoxygenase and TXB2 release. Bunaprolast is a potent inhibitor of LTB4 production in human whole blood.
LY3295668
T15815
LY3295668 is an effective and orally active and highly specific inhibitor of Aurora-A kinase (Ki: 0.8 nM and 1038 nM for AurA and AurB, respectively).
LY309887
T15813
LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.
ONO4057
T16395
ONO4057 is an antagonist of the Leukotriene B4 receptor (IC50: 0.7±0.3 μM).
CROCONAZOLE
T9878