Progesterone Receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone. In humans, PR is encoded by a single PGR gene residing on chromosome 11q22, it has two isoforms, PR-A and PR-B, that differ in their molecular weight. The PR-B is the positive regulator of the effects of progesterone, while PR-A serve to antagonize the effects of PR-B.

Cat. No.	Product name	CAS No.	Purity
T61864	Melengestrol acetate	2919-66-6	98%
T61864	Melengestrol acetate is a derivative of progesterone and acts as a corticosteroid hormone. Melengestrol acetate promotes endometrial proliferation delay of menst...
T3036	Dydrogesterone	152-62-5	98%
T3036	Dydrogesterone is a potent progestogen which can be used in progesterone deficiency studies.
T60056	Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl-	936345-34-5	98%
T60056	Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin e...
T28362	PF-02413873	936345-35-6	98%
T28362	PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gyne...
T0870	Altrenogest	850-52-2	100%
T0870	Altrenogest(A35957; RU2267), a progestogen, has structural relation with veterinary steroid trenbolone.
T1596	Chlormadinone acetate	302-22-7	98.18%
T1596	Chlormadinone acetate is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
T2231	Estradiol dipropionate	113-38-2	98.89%
T2231	Estradiol dipropionate is a synthetic ester, specifically the 3, 17-dipropanoyl ester, of the natural estrogen, estradiol.
T5040	Medroxyprogesterone	520-85-4	99.29%
T5040	Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.
T1261	Medroxyprogesterone Acetate	71-58-9	99.45%
T1261	Medroxyprogesterone acetate is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally...
T7974	Lynestrenol	52-76-6	99.47%
T7974	Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist
T1514	Norethindrone	68-22-4	99.55%
T1514	Norethindrone is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has...
T2567	Etonogestrel	54048-10-1	99.69%
T2567	Etonogestrel is a steroidal progestin used as hormonal contraceptives.
T1284	Megestrol acetate	595-33-5	99.72%
T1284	Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. ...
T1102	Mifepristone	84371-65-3	99.76%
T1102	Mifepristone is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T1429	17α-Hydroxyprogesterone	68-96-2	99.79%
T1429	Hydroxyprogesterone is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester...
T1541	Drospirenone	67392-87-4	99.81%
T1541	Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
T5174	Nestoron	7759-35-5	99.83%
T5174	Nestoron, a synthetic progestin, is a high-affinity agonist of the progesterone receptor (EC50: 10.3 nM).
T1263	Levonorgestrel	797-63-7	99.83%
T1263	Levonorgestrel is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum Fertilization.
T7537	Norgestimate	35189-28-7	99.87%
T7537	Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.
T0996	Ethynodiol diacetate	297-76-7	99.89%
T0996	Ethynodiol diacetate is a synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive.