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4-methylumbelliferyl-β-d-glucuronide hydrate

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4-Methylumbelliferyl-β-D-glucuronide hydrate
MUG
T18887881005-91-0
4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate (λex=362 nm, λem=445 nm).
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4-Methylumbelliferyl heptanoate
4-Methylumbelliferyl enanthate
T8364318319-92-1
4-Methylumbelliferyl heptanoate (4-Methylumbelliferyl enanthate) is a lipase fluorescent substrate that detects cell-mediated cytotoxicity and cell proliferation.
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5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside
T60017177966-52-8
5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.
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4-Nitrophenyl β-D-xylopyranoside
T784442001-96-9
4-Nitrophenyl β-D-xylopyranoside serves as a chromogenic substrate for β-xylosidase, facilitating the assessment of enzyme activity.
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4-Methylumbelliferyl-α-L-Fucopyranoside
4-ΜU-α-L-Fucopyranoside,4-Methylumbelliferyl-α-L-Fucoside
T8389754322-38-2
4-Methylumbelliferyl-α-L-fucopyranoside serves as a fluorogenic substrate for α-L-fucosidase, releasing 4-methylumbelliferone (4-ΜU) upon enzymatic cleavage by the enzyme. The fluorescence of 4-ΜU, with excitation/emission maxima at 350/440 nm, respectively, allows for the quantification of α-L-fucosidase activity.
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4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt)
T37566206443-06-3
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
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4-Methylumbelliferyl-β-D-Galactoside
T375696160-78-7
4-Methylumbelliferyl-β-D-galactoside (MUG) is a fluorogenic substrate for β-galactosidase (β-gal).1Hydrolysis of MUG by β-gal releases the fluorescent moiety 4-MU, which displays a pH-dependent excitation maximum of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm.2MUG has been used to detect β-gal activity in intact bacteria, yeast, and mammalian cells.1 1.Vidal-Aroca, F., Giannattasio, M., Brunelli, E., et al.One-step high-throughput assay for quantitative detection of β-galactosidase activity in intact Gram-negative bacteria, yeast, and mammalian cellsBiotechniques40(4)433-434(2006) 2.Zhi, H., Wang, J., Wang, S., et al.Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsuleJ. Spectrosc.1(1)147128(2013)
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7-10 days
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Fluorescein Di-β-D-Glucuronide
T75363134869-04-8
Fluorescein Di-β-D-Glucuronide, a fluorescent probe, enables non-invasive imaging of intestinal bacterial β-glucuronidase activity in nude mice. Its utilization for both in vitro and in vivo imaging provides valuable insights into bacterial β-glucuronidase activity, thereby enhancing pharmacodynamic research on specific inhibitors in animal models [1].
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4-Methylumbelliferyl oleate
T7838618323-58-5
4-Methylumbelliferyl oleate is a fluorescent substrate for lipases (Ex Em=320 450 nm), which can be cleaved by lipase and can be used to measure pancreatic inhibitory activity.
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4-Methylumbelliferyl sulfate potassium
4-MUS,4 MUS,Potassium 4-methylumbelliferyl sulfate Potassium 4 methylumbelliferyl sulfate Hymecromone sulfate,Potassium 4-methylumbelliferyl sulfate,4MUS
T8546015220-11-8
4-Methylumbelliferyl sulfate (potassium) is a fluorescent substrate widely used to identify sulfatase activity in biochemical and biomedical research. It features a sulfate group linked to a fluorescent molecule, cleaved by sulfatase enzymes to release a highly fluorescent product detectable via fluorescence microscopy or spectroscopy. This substrate enables precise detection and quantification of sulfatase enzymes across diverse biological samples.
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4-Methylumbelliferyl palmitate
T8331417695-48-6
4-Methylumbelliferyl palmitate serves as a potent fluorophore to assay acid lipase activity in human leukocytes, with its fluorescence significantly affected by acidity and solvent properties. In near-neutral aqueous solutions, it predominates in a neutral molecular form, emitting strong fluorescence at 445 nm, whereas in weakly alkaline solutions, it primarily exists in an anionic form, resulting in even stronger fluorescence at the same wavelength [1] [2].
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3-Indolyl-β-D-glucuronide
T8543335804-66-1
3-Indolyl-β-D-glucuronide is a chromogenic substrate for β-D-glucuronidase, used in detecting and counting E. coli, and produces a blue precipitate upon cleavage. It also serves as a novel indicator of renal failure in patients' plasma [1] [2].
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5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside
T89476341972-94-9
5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside is a chemiluminescent enzyme substrate used in diagnostic assays to detect bacterial and fungal infections, among other diseases.
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5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt
T64896129541-41-9
5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt is a useful organic compound for research related to life sciences. The catalog number is T64896 and the CAS number is 129541-41-9.
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7-10 days
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4-Methylumbelliferyl phosphate disodium
T7534022919-26-2
4-Methylumbelliferyl phosphate disodium (4-MUP), an anionic organophosphate, serves as a fluorogenic substrate for acid and alkaline phosphatases. Additionally, this compound acts as a simulant for nerve agents [1] [2] [3].
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4-Methylumbelliferyl phosphate
4-MUP
T188883368-04-5
4-Methylumbelliferyl phosphate (4-MUP) (4-MUP) is used as a fluorogenic substrate of alkaline phosphatases.
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N-(4-Methylumbelliferyl)-maleinimid
T86943211565-47-8
N-(4-Methylumbelliferyl)-maleinimid serves as a multifunctional dye utilized extensively across various domains. In biological experiments, dyes are pivotal for observing and analyzing cell structures, tracking biomolecules, assessing cell functions, differentiating cell types, detecting biomolecules, exploring tissue pathology, and monitoring microorganisms. Their utilization spans from fundamental scientific research to a broad spectrum of clinical diagnostics. Additionally, dyes find applications in conventional industries like textile dyeing and in emerging sectors, including functional textile processing, food pigments, and dye-sensitized solar cells.
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4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide
T8546180265-04-9
4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide serves as a fluorogenic substrate for the detection of α-N-acetylglucosaminidase [1].
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5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside
T8547915548-60-4
5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside, a chromogenic substrate, is widely utilized in molecular biology for β-galactosidase activity detection, especially in gene expression and reporter gene analysis. When cleaved by β-galactosidase, it yields a blue precipitate visible through microscopy or alternative detection techniques. Known for its high sensitivity and specificity, it remains a valuable asset in molecular biology research.
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Sodium 2,6-dibromo-4-(3-(3,5-dibromo-4-hydroxy-2-methylphenyl)-2,2-dioxido-3H-benzo[d][1,2]oxathiol-3-yl)-3-methylphenolate
T6478862625-32-5
Sodium 2,6-dibromo-4-(3-(3,5-dibromo-4-hydroxy-2-methylphenyl)-2,2-dioxido-3H-benzo[d][1,2]oxathiol-3-yl)-3-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T64788 and the CAS number is 62625-32-5.
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    4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt)
    T37568460085-45-4
    4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm. The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.
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    4-Methylumbelliferyl β-D-cellobioside
    T8810772626-61-0
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    4-Methylumbelliferyl β-cellotrioside
    T8331384325-18-8
    4-Methylumbelliferyl β-cellotrioside, a cellulose-derived fluorescent chromogenic substrate [1], is specifically hydrolyzed by β-glycosidases.
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    4-Methylumbelliferyl butyrate
    T8545917695-46-4
    4-Methylumbelliferyl butyrate (4-MUB) serves as a coumarin-based fluorogenic substrate for detecting M. catarrhalis C4-esterase. It converts into the blue-emissive compound 4-methylumbelliferone (4-MU [1]).
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