Biotin-PEG-Alk (MW 3400), a biotinylated polyethylene glycol (PEG) compound with an alkyne group, serves as a versatile click chemistry reagent. The biotin moiety acts as an enzyme cofactor desirable for protein labeling, PEG imparts hydrophilicity and aqueous solubility with minimal toxicity, and the alkyne (a type of acyclic hydrocarbon) facilitates efficient target binding by reacting with azides via copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Biotin-PEG-azide (MW 2000) is a biotinylated polyethylene glycol (PEG) compound featuring an azide group. Biotin serves as an enzyme cofactor suitable for protein labeling. PEG, noted for its hydrophilicity and water solubility, exhibits low toxicity. The azide functionality is a reasonably effective leaving group that participates in copper-catalyzed reactions with alkynes, enhancing the binding efficiency to biotin's targets.

Biotin-PEG-Alk (MW 10000) is a biotinylated polyethylene glycol (PEG) derivative featuring an alkyne group for click chemistry applications. This compound combines biotin, an enzyme co-factor used in protein labeling, with PEG, a hydrophilic, water-soluble, and low-toxicity polymer. The alkyne moiety facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azido-containing molecules, enhancing the efficiency of targeting biotin-binding entities.

Biotin-PEG-Alk (MW 600) is a biotin-labeled, alkyne-functionalized polyethylene glycol utilized as a click chemistry reagent for protein, peptide, and oligonucleotide modification [1]. Containing an alkyne group, it is designed for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.

Biotin-PEG-OH (MW 3400) is a polymer comprised of biotin and polyethylene glycol (PEG) units [1].

Biotin-PEG-Alk (MW 20000) is a biotin-labeled polyethylene glycol (PEG) derivative featuring a terminal alkyne group for efficient click chemistry applications. Serving as an enzymatic cofactor, biotin provides specific labeling of proteins, while the hydrophilic PEG moiety offers solubility and low toxicity. The alkyne functionality enables copper-catalyzed azide-alkyne cycloaddition (CuAAC), enhancing target binding through reaction with azide-modified molecules.

Biotin-PEG-azide (MW 3400) is a biotinylated polyethylene glycol (PEG) derivative featuring an azide group. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG is a hydrophilic, water-soluble, low-toxicity polymer. The azide group, a moderately good leaving group, undergoes Cu-catalyzed reactions with alkynes, enhancing the efficiency of target binding by biotin.

Biotin-PEG-OH (MW 20000) serves as a polyethylene glycol (PEG)-based PROTAC linker suitable for synthesizing PROTACs [1].

Biotin-PEG-Alk (MW 1000) is a biotinylated polyethylene glycol (PEG) derivative with alkyne functionality for click chemistry applications. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG provides hydrophilic, water-soluble, and low-toxicity characteristics. The alkyne group (Alk) facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with azido-modified molecules, enhancing the compound's ability to target and bind with biotin receptors.

Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative featuring biotin labels at each terminal end. As an enzyme co-factor, biotin facilitates protein labeling, while PEG, known for its hydrophilic nature and low toxicity, confers water solubility to the compound.

Biotin-PEG-Alk (MW 2000) is a biotin-labeled polyethylene glycol (PEG) derivative featuring an alkyne group for click chemistry applications. This compound, efficiently binding to biotin targets due to the alkyne moiety that can react with azides, serves as a versatile tool in bioconjugation processes, including the labeling of proteins. The hydrophilic nature of PEG ensures solubility in aqueous environments and minimal toxicity, while the alkyne (an acyclic hydrocarbon that may be branched or unbranched) facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC), enhancing biotin-avidin interaction assays and molecular assembly.

Biotin-PEG-Thiol (MW 2000) is an active, pegylated compound that binds to streptavidin or antibiotin with high affinity and specificity. It is capable of modifying biomolecules, proteins, peptides, and other small molecular materials. This compound is commonly utilized in agent release research and the development of novel nanomaterials [1].

Amine-PEG3-Biotin can be used as a signal amplification label.