T11896 |
LV-320
|
2449093-46-1
|
98%
|
|
LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC 50 of 24.5 μM and a K d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flu...
|
T13705 |
GLPG2451
|
2055015-61-5
|
98%
|
|
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1...
|
T16474 |
Petesicatib
|
1252637-35-6
|
98%
|
|
Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
|
T10924 |
Cysteine protease inhibitor-2
|
612048-23-4
|
98%
|
|
Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μ...
|
T16394 |
ONO-5334
|
868273-90-9
|
98%
|
|
ONO-5334 is an effective and selective cathepsin K inhibitor (Ki: 0.10 nM, 0.049 nM, and 0.85 nM for human, rabbit, and rat cathepsin K, respectively). ONO-5334 ...
|
T11846 |
LHVS
|
170111-28-1
|
98%
|
|
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine proteas...
|
T12819 |
S130
|
1160852-22-1
|
98%
|
|
S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.
|
T13439 |
(RS)-Butyryltimolol
|
2320274-78-8
|
98%
|
|
(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol is an effective prodrug of Timolol that improves the corneal penetration of Timolol [1]. Bu...
|
T11554 |
Cathepsin Inhibitor 2
|
1017931-53-1
|
98%
|
|
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
|
T8677 |
3,4 Dichloroisocoumarin
|
51050-59-0
|
99.9%
|
|
3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor
|
T0789 |
PMSF
|
329-98-6
|
99.9%
|
|
Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthe...
|
T15641 |
K777
|
233277-99-1
|
99.71%
|
|
K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 a...
|
TJS2216 |
Aurantiamide acetate
|
56121-42-7
|
99.68%
|
|
Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selectiv...
|
T6015 |
Cathepsin Inhibitor 1
|
225120-65-0
|
99.68%
|
|
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
|
T6040 |
Aloxistatin
|
88321-09-9
|
99.47%
|
|
Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable i...
|
T60812 |
Cathepsin X-IN-1
|
2418577-51-0
|
99.46%
|
|
Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].
|
T6738 |
Z-FA-FMK
|
197855-65-5
|
99.43%
|
|
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
|
T9710 |
Dazcapistat
|
2221010-42-8
|
99.41%
|
|
Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.
|
T12051 |
MIV-247
|
1352817-76-5
|
99.31%
|
|
MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuat...
|
T65868 |
Z-Lys-OH
|
2212-75-1
|
99.11%
|
|
Z-Lys-OH is a competitive inhibitor of papain, a lysine derivative.
|