TN4383 |
Kazinol U
|
1238116-48-7
|
98%
|
|
Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-κB pathway in pancreatic β-cells reduces ce...
|
T3775 |
Armepavine
|
524-20-9
|
98%
|
|
Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBP pathways. It improves experimental autoimmun...
|
T14669 |
BMS-066
|
914946-88-6
|
98%
|
|
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
|
TN3635 |
Chlojaponilactone B
|
1449382-91-5
|
98%
|
|
Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264...
|
T14508 |
Bay 65-1942 hydrochloride
|
600734-06-3
|
98%
|
|
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
|
T13097 |
TBK1/IKKε-IN-1
|
2058264-32-5
|
98%
|
|
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
T11633 |
IKK-IN-1
|
406211-06-1
|
98%
|
|
IKK-IN-1 is an inhibitor of IKK.
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
TN4986 |
Selinidin
|
19427-82-8
|
98%
|
|
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
|
T15558 |
GSK319347A
|
862812-98-4
|
98%
|
|
GSK319347A is a TBK1 and IKKε dual inhibitor (IC50s: 93 nM and 469 nM, respectively). GSK319347A inhibits IKK2 (IC50: 790 nM).
|
TN2534 |
1-Hydroxy-2,3,5-trimethoxyxanthone
|
22804-49-5
|
98%
|
|
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
|
TN4683 |
Nyasol
|
96895-25-9
|
98%
|
|
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ...
|
TN4318 |
Isophysalin A
|
1363398-67-7
|
98%
|
|
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production in...
|
TN3539 |
Broussonin A
|
73731-87-0
|
98%
|
|
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tra...
|
TN4779 |
Physalin O
|
120849-18-5
|
98%
|
|
Physalin O possesses anti-inflammatory activity, it exhibited conjugating abilities with GSH and also showed significant nitric oxide (NO) production inhibiting ...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
T14567 |
BI605906
|
960293-88-3
|
98%
|
|
BI605906 is an inhibitor of IKKβ. When assayed at 0.1 mM ATP, the IC50 value is 380 nM.
|
T10472L |
Bay 65-1942 free base
|
600734-02-9
|
98%
|
|
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
|