T4299 |
AS-2444697
|
1287665-60-4
|
98%
|
|
AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits hum...
|
T9631 |
IRAK-4 protein kinase inhibitor 2
|
301675-24-1
|
98%
|
|
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).
|
T9203 |
JH-X-119-01
|
2227368-54-7
|
98%
|
|
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
|
T62714 |
IRAK4-IN-20
|
1931994-80-7
|
98%
|
|
IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM). IRAK4-IN-20, which has anti-inflammatory, antitumor and anticancer effects, is often us...
|
T60012 |
HS-243
|
848249-10-5
|
98%
|
|
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
|
T5094 |
IRAK inhibitor 1
|
1042224-63-4
|
98%
|
|
IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).
|
TQ0167 |
Zimlovisertib
|
1817626-54-2
|
98%
|
|
PF06650833 is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and PB...
|
T37082 |
HS271
|
2410393-15-4
|
98%
|
|
HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM). HS271 shows excellent enzymatic and cellular activities, as well as excelle...
|
T14367 |
AZ1495
|
2196204-23-4
|
98%
|
|
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. W...
|
T37076 |
Zabedosertib
|
1931994-81-8
|
98%
|
|
Zabedosertib is an inhibitor of IRAK4 with immunomodulatory potential. Zabedosertib protects against acute respiratory distress syndrome, a new study suggests.
|
T5110 |
IRAK inhibitor 6
|
1042672-97-8
|
98%
|
|
IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).
|
T7755 |
Thalidomide 4-fluoride
|
835616-60-9
|
98%
|
|
Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thali...
|
T11673 |
IRAK4-IN-4
|
1850276-58-2
|
98%
|
|
IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an I...
|
T5354 |
IRAK4-IN-7
|
1801343-74-7
|
98%
|
|
CA-4948 (previously AU-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.
|
T9027 |
CA-4948
|
1801344-14-8
|
98%
|
|
Emavusertib is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.
|
T2822 |
Ginsenoside Rb1
|
41753-43-9
|
98%
|
|
Ginsenoside Rb1 is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
|
T4140 |
IRAK4-IN-1
|
1820787-94-7
|
98%
|
|
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
|
T7035 |
ANTHRAQUINONE-2-CARBOXYLIC ACID
|
117-78-2
|
98%
|
|
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of frui...
|
T2457 |
IRAK-1-4 Inhibitor I
|
509093-47-4
|
98%
|
|
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.
|
T11670 |
IRAK inhibitor 3
|
1012343-93-9
|
98%
|
|
IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator.
|