Melanocortin Receptor

Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin receptor system:MC1R，MC2R，MC3R，MC4R，MC5R.

Cat. No.	Product name	CAS No.	Purity
T12882	Setmelanotide	920014-72-8	98%
T12882	Setmelanotide is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
TP1011L	ACTH (1-17) acetate		98%
TP1011L	ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
T7627	Adrenocorticotropic Hormone (ACTH) (4-10), human	4037-01-8	98%
T7627	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
T16879L	SHU 9119 acetate	T16879L	98%
T16879L	SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC...
TP1004L	Beta-MSH (1-22) (human) acetate		98%
TP1004L	β-Melanocyte Stimulating Hormone (MSH), human, a 22-peptide, is an endogenous melanocortin-4 receptor (MC4-R) agonist.
TP1889	MCL0020	475498-26-1	98%
TP1889	Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly...
T5464	JNJ-10229570	524923-88-4	98%
T5464	JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the produc...
T7627L	Adrenocorticotropic Hormone (ACTH) (4-10) TFA	T7627L	98%
T7627L	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
T8485	THIQ	312637-48-2	98%
T8485	THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
T9596	AP1189 acetate	959850-74-9	98%
T9596	AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
TP2212L	A-MSH, amide Acetate(581-05-5 free base)	TP2212L	98%
TP2212L	a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities....
TP1101	Nonapeptide-1 acetate salt (158563-45-2 free base)	TP1101	98%
TP1101	Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Nonapeptide-1 acetate salt...
TP1952L	PG 106 acetate		98%
TP1952L	PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with t...
T7589	Afamelanotide acetate	1566590-77-9	98%
T7589	Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Pro...
T7608	Bremelanotide Acetate	1607799-13-2	98%
T7608	Bremelanotide is an agonist of melanocortin receptor (MCR) .
T25310	Dersimelagon	1835256-48-8	98%
T25310	Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cyn...
TP1578L	Neuropeptide EI, rat acetate	TP1578L	98%
TP1578L	Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
T12882L	Setmelanotide Acetate(920014-72-8 free base)	2759937-80-7	98%
T12882L	Setmelanotide Acetate is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
TP1248L	ACTH 11-24 acetate(4237-93-8 free base)	79190-56-0	98%
TP1248L	ACTH (11-24) acetate is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39)...
TP1893L1	[D-Trp8]-γ-MSH acetate(321351-81-9 free base)	TP1893L1	98%
TP1893L1	Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammato...