T0179 |
Ticagrelor
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Ticagrelor, produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The ...
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T6172 |
MRS 2578
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MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.
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T8582 |
1-[(5-methylisoxazol-3-yl)methyl]piperazine
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Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI) is a P2Y12 inhibitor.
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T11177 |
Elinogrel
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Elinogrel is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 nM and exhibits potent antiplatelet effects.
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T0182 |
Clopidogrel
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Clopidogrel, a P2Y12 receptor antagonist, decreases platelet aggregation.
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T4706 |
Uridine-5'-diphosphate disodium salt
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UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstr...
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T21059 |
Ticagrelor metabolite M5
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Ticagrelor metabolite M5 is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster an...
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T5036 |
Cangrelor tetrasodium
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Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.
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T12164 |
N6-(4-Hydroxybenzyl)adenosine
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N6-(4-Hydroxybenzyl)adenosine is a platelet aggregation inhibitor.
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T4132 |
BPTU
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Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contrac...
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T0182L |
Clopidogrel hydrogen sulfate
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(S)-(+)-Clopidogrel hydrogensulfate, a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and ...
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T0182L2 |
(±) Clopidogrel hydrogen sulfate
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Clopidogrel, an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cere...
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T3536 |
AZD1283
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AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibi...
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T7423 |
Diquafosol tetrasodium
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Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium improves tear film stability...
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T0230 |
Prasugrel
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Prasugrel is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANG...
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T6952 |
Prasugrel Hydrochloride
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Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome...
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T4743 |
Uridine 5′-diphosphoglucose disodium salt
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UDP-Glucose sodium salt is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 =...
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