Protease-activated Receptor

Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain. They are highly expressed in platelets, and also on endothelial cells, myocytes and neurons.

Cat. No.	Product name	CAS No.	Purity
T7380	Protease-Activated Receptor-4	245443-52-1
T7380	Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy
T7573	TFLLR-NH2	197794-83-5
T7573	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
T4186	AC-264613	1051487-82-1	98%
T4186	AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin...
T7496	Thrombin Receptor Activator for Peptide 5 (TRAP-5)	141685-53-2	98%
T7496	Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in c...
T7623L	PAR-4 Agonist Peptide, amide acetate	T7623L	98%
T7623L	PAR-4 Agonist Peptide, amide acetate is an agonist of proteinase-activated receptor-4 (PAR-4).
T7013	Vorapaxar	618385-01-6	99.93%
T7013	Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).
T3098	Vorapaxar sulfate	705260-08-8	99.9%
T3098	Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.
T8917	PAR-2-IN-1	1690176-75-0	99.79%
T8917	PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.
T41190	AY 77	1835734-92-3	99.7%
T41190	AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ...
T7740	Protease-Activated Receptor-4 diTFA	T7740	99.42%
T7740	Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist
T2370	AC-55541	916170-19-9	99.35%
T2370	AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobiliz...
TP1904L	FSLLRY-NH2 TFA(245329-02-6 free base)	TP1904L	99.32%
TP1904L	FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR...
T63966	BMS-986141	1478711-48-6	99.11%
T63966	BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibi...
T21699L	VKGILS-NH2 Acetate	T21699L	98.83%
T21699L	VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.
T12870	SCH79797 dihydrochloride	1216720-69-2	98.58%
T12870	SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihyd...
T38852L	TRAP-6 amide acetate		98.55%
T38852L	TRAP-6 amide acetate is a PAR-1 thrombin receptor agonist peptide[1].
TP1046L	PAR-2 Activating Peptide acetate	TP1046L	98.5%
TP1046L	PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
TQ0012	AZ3451	2100284-59-9	98.44%
TQ0012	AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
TP1046	SLIGRL-NH2	171436-38-7	98.29%
TP1046	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus.
T1986	Atopaxar	751475-53-3	98.25%
T1986	Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Corona...