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Reverse Transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases are used by retroviruses to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes, and by some non-retroviruses such as the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses.
Cat. No. Product name CAS No. Purity Chemical Structure
T27625 IQP-0528 301297-45-0 98%
IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and sho...
T11189 Emtricitabine S-oxide 152128-77-3 98%
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine su...
T3730 Methyl gallate 99-24-1 98%
Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
T6214 Emtricitabine 143491-57-0 98%
Emtricitabine (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus....
T1416 Zidovudine 30516-87-1 98%
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
T6367 Abacavir sulfate 188062-50-2 98%
Abacavir, a nucleoside analogue, effectively utilize its antiviral activity
T2551 Etravirine 269055-15-4 98%
Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that con...
T0153 Oltipraz 64224-21-1 98%
Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as g...
T4326 AG 555 133550-34-2 98%
AG 555 is an EGFR tyrosine kinase inhibitor.
T3632 Doravirine 1338225-97-0 98%
Doravirine is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.
T12609 R-10015 2097938-51-5 98%
R-10015 is a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket(IC50 of 38 nM for human LIMK1),and a broad-spectrum a...
T9223 RO-0335 867365-76-2 98%
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) a...
T19963 Alizarin Complexone 3952-78-1 98%
Alizarin Complexone is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent f...
T6519 Gramine 87-52-5 98%
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for A...
T27154 Dexelvucitabine 134379-77-4 98%
Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
T2901 Daidzin 552-66-9 98%
Daidzin is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T5981 2,2'-Anhydrouridine 3736-77-4 98%
2,2'-Cyclouridine is a research tool for antiviral and anticancer studies.
T2160 Suramin Sodium Salt 129-46-4 98%
Suramin Sodium is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various gro...
T16098 Islatravir 865363-93-5 98%
Islatravir is an effective anti-HIV-1 agent. It acting as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-...
T68103 MK-6186 1034474-19-5 98%
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity for the study of viral infections.
IQP-0528
T27625
IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and sho...
Emtricitabine S-oxide
T11189
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine su...
Methyl gallate
T3730
Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
Emtricitabine
T6214
Emtricitabine (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus....
Zidovudine
T1416
Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
Abacavir sulfate
T6367
Abacavir, a nucleoside analogue, effectively utilize its antiviral activity
Etravirine
T2551
Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that con...
Oltipraz
T0153
Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as g...
AG 555
T4326
AG 555 is an EGFR tyrosine kinase inhibitor.
Doravirine
T3632
Doravirine is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.
R-10015
T12609
R-10015 is a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket(IC50 of 38 nM for human LIMK1),and a broad-spectrum a...
RO-0335
T9223
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) a...
Alizarin Complexone
T19963
Alizarin Complexone is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent f...
Gramine
T6519
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for A...
Dexelvucitabine
T27154
Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
Daidzin
T2901
Daidzin is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
2,2'-Anhydrouridine
T5981
2,2'-Cyclouridine is a research tool for antiviral and anticancer studies.
Suramin Sodium Salt
T2160
Suramin Sodium is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various gro...
Islatravir
T16098
Islatravir is an effective anti-HIV-1 agent. It acting as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-...
MK-6186
T68103
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity for the study of viral infections.
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