Reverse Transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases are used by retroviruses to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes, and by some non-retroviruses such as the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses.

Cat. No.	Product name	CAS No.	Purity
T27625	IQP-0528	301297-45-0	98%
T27625	IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and sho...
T11189	Emtricitabine S-oxide	152128-77-3	98%
T11189	Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine su...
T3730	Methyl gallate	99-24-1	98%
T3730	Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
T6214	Emtricitabine	143491-57-0	98%
T6214	Emtricitabine (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus....
T1416	Zidovudine	30516-87-1	98%
T1416	Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the i...
T6367	Abacavir sulfate	188062-50-2	98%
T6367	Abacavir, a nucleoside analogue, effectively utilize its antiviral activity
T2551	Etravirine	269055-15-4	98%
T2551	Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that con...
T0153	Oltipraz	64224-21-1	98%
T0153	Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as g...
T4326	AG 555	133550-34-2	98%
T4326	AG 555 is an EGFR tyrosine kinase inhibitor.
T3632	Doravirine	1338225-97-0	98%
T3632	Doravirine is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.
T12609	R-10015	2097938-51-5	98%
T12609	R-10015 is a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket(IC50 of 38 nM for human LIMK1),and a broad-spectrum a...
T9223	RO-0335	867365-76-2	98%
T9223	RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) a...
T19963	Alizarin Complexone	3952-78-1	98%
T19963	Alizarin Complexone is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent f...
T6519	Gramine	87-52-5	98%
T6519	Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for A...
T27154	Dexelvucitabine	134379-77-4	98%
T27154	Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
T2901	Daidzin	552-66-9	98%
T2901	Daidzin is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T5981	2,2'-Anhydrouridine	3736-77-4	98%
T5981	2,2'-Cyclouridine is a research tool for antiviral and anticancer studies.
T2160	Suramin Sodium Salt	129-46-4	98%
T2160	Suramin Sodium is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various gro...
T16098	Islatravir	865363-93-5	98%
T16098	Islatravir is an effective anti-HIV-1 agent. It acting as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-...
T68103	MK-6186	1034474-19-5	98%
T68103	MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity for the study of viral infections.