T15602 |
ITX3
|
347323-96-0
|
98%
|
|
ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange ...
|
TP2327L |
Y16 acetate(429653-73-6 free base)
|
TP2327L
|
98%
|
|
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
|
T12452 |
Digeranyl bisphosphonate
|
878143-03-4
|
98%
|
|
Digeranyl bisphosphonate is a potent inhibitor of geranylgeranylpyrophosphate (GGPP) synthase.
|
T16746 |
Rhosin
|
1173671-63-0
|
98%
|
|
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin...
|
TP2130L |
Rac1 Inhibitor F56, control peptide acetate
|
TP2130L
|
98%
|
|
Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not...
|
T22991 |
ML-099
|
496775-95-2
|
98%
|
|
pan activator of Ras-related GTPases
|
T9986 |
(E/Z)-ZINC09659342
|
591726-26-0
|
98%
|
|
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
|
T14004 |
1A-116
|
1430208-73-3
|
98%
|
|
1A-116 is a specific inhibitor of Rac1 .
|
T24833 |
ZINC69391
|
303094-67-9
|
98%
|
|
ZINC69391 is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, red...
|
T3553 |
Y16
|
429653-73-6
|
100%
|
|
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
|
T2427 |
EHop-016
|
1380432-32-5
|
97.69%
|
|
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
|
T24642 |
YH-306
|
1373764-75-0
|
97.87%
|
|
YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
|
T8473 |
MLS000532223
|
16616-39-0
|
98.11%
|
|
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
|
T7764 |
CCG-222740
|
1922098-69-8
|
98.79%
|
|
CCG-222740 is an inhibitor of Rho/MRTF pathway
|
T16745 |
Rhosin hydrochloride
|
1281870-42-5
|
98.92%
|
|
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0...
|
TP2131L |
Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
|
TP2131L
|
98.96%
|
|
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with...
|
T1237 |
Azathioprine
|
446-86-6
|
99.25%
|
|
Azathioprine, an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
|
T4306 |
CCG-203971
|
1443437-74-8
|
99.35%
|
|
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This...
|
T6483 |
EHT 1864
|
754240-09-0
|
99.42%
|
|
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
|
T6342 |
NSC 23766 trihydrochloride
|
1177865-17-6
|
99.54%
|
|
NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
|