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Rho

Rho protein functions as a hexamer of a single polypeptide chain with 419 residues, which is the product of the rho gene. It is an RNA-binding protein with the capacity to hydrolyze ATP and other nucleoside triphosphates.
Cat. No. Product name CAS No. Purity Chemical Structure
T15602 ITX3 347323-96-0 98%
ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange ...
TP2327L Y16 acetate(429653-73-6 free base) TP2327L 98%
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
T12452 Digeranyl bisphosphonate 878143-03-4 98%
Digeranyl bisphosphonate is a potent inhibitor of geranylgeranylpyrophosphate (GGPP) synthase.
T16746 Rhosin 1173671-63-0 98%
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin...
TP2130L Rac1 Inhibitor F56, control peptide acetate TP2130L 98%
Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not...
T22991 ML-099 496775-95-2 98%
pan activator of Ras-related GTPases
T9986 (E/Z)-ZINC09659342 591726-26-0 98%
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
T14004 1A-116 1430208-73-3 98%
1A-116 is a specific inhibitor of Rac1 .
T24833 ZINC69391 303094-67-9 98%
ZINC69391 is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, red...
T3553 Y16 429653-73-6 100%
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
T2427 EHop-016 1380432-32-5 97.69%
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
T24642 YH-306 1373764-75-0 97.87%
YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
T8473 MLS000532223 16616-39-0 98.11%
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
T7764 CCG-222740 1922098-69-8 98.79%
CCG-222740 is an inhibitor of Rho/MRTF pathway
T16745 Rhosin hydrochloride 1281870-42-5 98.92%
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0...
TP2131L Rac1 Inhibitor W56 acetate(1095179-01-3 free base) TP2131L 98.96%
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with...
T1237 Azathioprine 446-86-6 99.25%
Azathioprine, an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
T4306 CCG-203971 1443437-74-8 99.35%
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This...
T6483 EHT 1864 754240-09-0 99.42%
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
T6342 NSC 23766 trihydrochloride 1177865-17-6 99.54%
NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
ITX3
T15602
ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange ...
Y16 acetate(429653-73-6 free base)
TP2327L
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
Digeranyl bisphosphonate
T12452
Digeranyl bisphosphonate is a potent inhibitor of geranylgeranylpyrophosphate (GGPP) synthase.
Rhosin
T16746
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin...
Rac1 Inhibitor F56, control peptide acetate
TP2130L
Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not...
ML-099
T22991
pan activator of Ras-related GTPases
(E/Z)-ZINC09659342
T9986
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
1A-116
T14004
1A-116 is a specific inhibitor of Rac1 .
ZINC69391
T24833
ZINC69391 is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, red...
Y16
T3553
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
EHop-016
T2427
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
YH-306
T24642
YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
MLS000532223
T8473
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
CCG-222740
T7764
CCG-222740 is an inhibitor of Rho/MRTF pathway
Rhosin hydrochloride
T16745
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0...
Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
TP2131L
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with...
Azathioprine
T1237
Azathioprine, an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
CCG-203971
T4306
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This...
EHT 1864
T6483
EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
NSC 23766 trihydrochloride
T6342
NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
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