Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.

Cat No.	product name
T2A2524	2-Hydroxy-4-methoxybenzaldehyde	2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a pot...
T4920	2-Ketoglutaric acid Sodium	alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase a...
T3923	Calycosin	Calycosin acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 famil...
T3S1068	Oxyresveratrol	1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gli...
T5985	Glycolic acid	Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
TCS1709	BENZYLACETONE	Used in soap perfumes.
T3745	3,4-Dimethoxyphenol	3, 4-Dimethoxyphenol is an active biochemical.
T1738	Taxifolin	Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
T3734	3',4'-Dihydroxyacetophenone	3', 4'-Dihydroxyacetophenone is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity.
TN1772	Isoastilbin	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) wit...
T4185	Lavendustin C	Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
T4911	α-Arbutin	Alpha-arbutin is a synthetic and functional active ingredient for skin lightening.
T5980	2-Ketoglutaric acid	2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination rea...
T7394	Toceranib Phosphate	Toceranib phosphate, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR
T8697	ZAP-180013	ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).
T7052	Gnetol	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly sup...
T0314	Hexylresorcinol	Hexylresorcinol is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
TN1296	5-Feruloylquinic acid	5-O-Feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated...
T7966	3-O-Ethyl-L-ascorbic acid	3-O-Ethyl-L-ascorbic acid is a chemical compound
T2S0973	2-Methoxycinnamic acid	1. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity.
T0666	4-Chlorosalicylic acid	4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
T3403	Glabridin	Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-gluc...
T3709	XMD8-87	XMD8-87 is a TNK2 inhibitor with activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation muta...
T3569	SU5214	SU 5214 is a modulator of tyrosine kinase signal transduction.
T4S1658	Benzoyloxypaeoniflorin	Benzoyloxypeoniflorin is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coa...
T3710	XMD16-5	XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted m...
T4587	Mirificin	Puerarin Apioside is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.
T4182	Lavendustin B	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gro...
T1188	Mizoribine	Mizoribine belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T4S0998	Trifolirhizin	Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirh...
T6S1597	Mulberroside A	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
TCS2170	2,5-Dihydroxyacetophenone	1. 2, 5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2, 5-Dihydroxyacetophenone treatment can induce a sustained activation of J...
T5889	Kojic acid	Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase.
TN1804	Isosilybin A	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC5...
TN1928	Methyl rosmarinate	Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmari...
T5552	Methyl cinnamate	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
T2340	AC1NS4RE	It is a tyrosine kinase inhibitor.
T2742	Aloin(mixture of A&B)	Aloin(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
TN2672	2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran	2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
T8087	Tropolone	Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
T7714	Temocapil	Temocapril is an inhibitor of tyrosine kinase.
T7438	3,5-Dimethoxyphenol	3,5-Dimethoxyphenol as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.
T7125	4-Butylresorcinol	4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
TC0017	Haplopine	Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
TMA0593	Broussoflavonol F	Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggrega...
TMA2563	Pedalitin	Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosm...
TMA0003	Trans-caffeic acid	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
TN1314	6-Hydroxykaempferol	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TN1545	D-Tyrosine	D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine inhibits biofilm formatio...
TN2280	Trametenolic acid	Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...