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Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.
Cat No. product name
T2A2524 2-Hydroxy-4-methoxybenzaldehyde 2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a pot...
T4920 2-Ketoglutaric acid Sodium alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase a...
T3923 Calycosin Calycosin acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 famil...
T3S1068 Oxyresveratrol 1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gli...
T5985 Glycolic acid Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
TCS1709 BENZYLACETONE Used in soap perfumes.
T3745 3,4-Dimethoxyphenol 3, 4-Dimethoxyphenol is an active biochemical.
T1738 Taxifolin Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
T3734 3',4'-Dihydroxyacetophenone 3', 4'-Dihydroxyacetophenone is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity.
TN1772 Isoastilbin Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) wit...
T4185 Lavendustin C Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
T4911 α-Arbutin Alpha-arbutin is a synthetic and functional active ingredient for skin lightening.
T5980 2-Ketoglutaric acid 2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination rea...
T7394 Toceranib Phosphate Toceranib phosphate, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR
T8697 ZAP-180013 ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).
T7052 Gnetol Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly sup...
T0314 Hexylresorcinol Hexylresorcinol is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
TN1296 5-Feruloylquinic acid 5-O-Feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated...
T7966 3-O-Ethyl-L-ascorbic acid 3-O-Ethyl-L-ascorbic acid is a chemical compound
T2S0973 2-Methoxycinnamic acid 1. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity.
T0666 4-Chlorosalicylic acid 4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
T3403 Glabridin Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-gluc...
T3709 XMD8-87 XMD8-87 is a TNK2 inhibitor with activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation muta...
T3569 SU5214 SU 5214 is a modulator of tyrosine kinase signal transduction.
T4S1658 Benzoyloxypaeoniflorin Benzoyloxypeoniflorin is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coa...
T3710 XMD16-5 XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted m...
T4587 Mirificin Puerarin Apioside is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.
T4182 Lavendustin B Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gro...
T1188 Mizoribine Mizoribine belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T4S0998 Trifolirhizin Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirh...
T6S1597 Mulberroside A 1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
TCS2170 2,5-Dihydroxyacetophenone 1. 2, 5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2, 5-Dihydroxyacetophenone treatment can induce a sustained activation of J...
T5889 Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase.
TN1804 Isosilybin A Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC5...
TN1928 Methyl rosmarinate Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmari...
T5552 Methyl cinnamate Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
T2340 AC1NS4RE It is a tyrosine kinase inhibitor.
T2742 Aloin(mixture of A&B) Aloin(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
TN2672 2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran 2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
T8087 Tropolone Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
T7714 Temocapil Temocapril is an inhibitor of tyrosine kinase.
T7438 3,5-Dimethoxyphenol 3,5-Dimethoxyphenol as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.
T7125 4-Butylresorcinol 4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
TC0017 Haplopine Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
TMA0593 Broussoflavonol F Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggrega...
TMA2563 Pedalitin Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosm...
TMA0003 Trans-caffeic acid Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
TN1314 6-Hydroxykaempferol 6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TN1545 D-Tyrosine D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine inhibits biofilm formatio...
TN2280 Trametenolic acid Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
2-Hydroxy-4-methoxybenzaldehyde
T2A2524
2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a pot...
2-Ketoglutaric acid Sodium
T4920
alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase a...
Calycosin
T3923
Calycosin acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 famil...
Oxyresveratrol
T3S1068
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gli...
Glycolic acid
T5985
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
BENZYLACETONE
TCS1709
Used in soap perfumes.
3,4-Dimethoxyphenol
T3745
3, 4-Dimethoxyphenol is an active biochemical.
Taxifolin
T1738
Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
3',4'-Dihydroxyacetophenone
T3734
3', 4'-Dihydroxyacetophenone is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity.
Isoastilbin
TN1772
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) wit...
lavendustin C
T4185
Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
α-Arbutin
T4911
Alpha-arbutin is a synthetic and functional active ingredient for skin lightening.
2-Ketoglutaric acid
T5980
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination rea...
Toceranib Phosphate
T7394
Toceranib phosphate, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR
ZAP-180013
T8697
ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).
Gnetol
T7052
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly sup...
Hexylresorcinol
T0314
Hexylresorcinol is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
5-Feruloylquinic acid
TN1296
5-O-Feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated...
3-O-Ethyl-L-ascorbic acid
T7966
3-O-Ethyl-L-ascorbic acid is a chemical compound
2-Methoxycinnamic acid
T2S0973
1. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity.
4-Chlorosalicylic acid
T0666
4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
Glabridin
T3403
Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-gluc...
XMD8-87
T3709
XMD8-87 is a TNK2 inhibitor with activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation muta...
SU5214
T3569
SU 5214 is a modulator of tyrosine kinase signal transduction.
Benzoyloxypaeoniflorin
T4S1658
Benzoyloxypeoniflorin is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coa...
XMD16-5
T3710
XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted m...
Mirificin
T4587
Puerarin Apioside is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.
lavendustin B
T4182
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gro...
Mizoribine
T1188
Mizoribine belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
Trifolirhizin
T4S0998
Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirh...
Mulberroside A
T6S1597
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
2,5-Dihydroxyacetophenone
TCS2170
1. 2, 5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2, 5-Dihydroxyacetophenone treatment can induce a sustained activation of J...
Kojic acid
T5889
Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase.
Isosilybin A
TN1804
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (I...
Methyl rosmarinate
TN1928
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmari...
Methyl cinnamate
T5552
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
AC1NS4RE
T2340
It is a tyrosine kinase inhibitor.
Aloin(mixture of A&B)
T2742
Aloin(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran
TN2672
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
Tropolone
T8087
Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
Temocapil
T7714
Temocapril is an inhibitor of tyrosine kinase.
3,5-Dimethoxyphenol
T7438
3,5-Dimethoxyphenol as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.
4-Butylresorcinol
T7125
4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
Haplopine
TC0017
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
Broussoflavonol F
TMA0593
Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggrega...
Pedalitin
TMA2563
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl ros...
Trans-caffeic acid
TMA0003
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
6-Hydroxykaempferol
TN1314
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
D-Tyrosine
TN1545
D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine inhibits biofilm formatio...
Trametenolic acid
TN2280
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and ...
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