Tyrosinase

Cat No.	product name
T0314	Hexylresorcinol	Hexylresorcinol is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T0357	Potassium iodide	Potassium iodide is used as the treatment of overactive thyroid and as protection of the thyroid gland from the influences of radiation from swallowed or inhale...
T0473	Arbutin	Arbutin(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent th...
T0759	Monobenzone	Monobenzone is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone is by mea...
T1188	Mizoribine	Mizoribine belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T1210	Sodium etidronate	Etidronate Disodium is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, et...
T1738	Taxifolin	Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
T3403	Glabridin	Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction,through regulating the synthesis and activity of iNOS under high-gluc...
T3737	Hydroumbellic acid	Hydroumbellic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid. It i...
T3827	Rhein-8-glucoside calcium salt	Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
T3923	Calycosin	Calycosin acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 fami...
T4185	lavendustin C	Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
T6463	Deoxyarbutin	DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.
T4182	lavendustin B	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gr...
T4291	(+)-Isocorydine hydrochloride	(+)-Isocorydine is a eukaryote protein kinases Inhibitor.
T2P2923	Stearic acid	1. Stearic Acid can reduce metastatic tumor burden. 2. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocyte...
T3S1068	Oxyresveratrol	1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive g...
T3S1612	kuwanon G	1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment fo...
TCS2170	Acetylhydroquinone	1. 2,5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JN...
T7052	Gnetol	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly su...
T5552	Methyl cinnamate	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
T5755	Aloesin	Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first...
T7125	4-Butylresorcinol	4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
T5985	Glycolic acid	Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
T7438	3,5-Dimethoxyphenol	3,5-Dimethoxyphenol as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.
T7714	Temocapil	Temocapril is an inhibitor of tyrosine kinase.
T4183	lavendustin A	lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
T6S1597	Mulberroside A	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycos...
T3382	Wilforlide A	Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. High-dose wilforlide A has obvious anti-inflammatory effect,...
T0666	4-Chlorosalicylic acid	4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
T8087	Tropolone	Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
TN1314	6-Hydroxykaempferol	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TN1325	6-Prenylnaringenin	6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin.
TN1690	Glabrene	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likel...
TN1928	Methyl rosmarinate	Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteina...
TN1958	Mulberroside F	Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity th...
TN2026	Oxyresveratrol 3'-O-beta-D-glucopyranoside	Oxyresveratrol-3'-O-beta-D-glucopyranoside shows tyrosinase inhibitory activity, it may be a potential candidate as skin-whitening agents without posing any ser...
TN2078	Pinocembrin chalcone	Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic...
TN2148	Retusin	Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well...
TN2280	Trametenolic acid	Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and...
TN2288	Uralenol	Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as ...
TN2303	Viscumneoside III	Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics.
TN1772	Isoastilbin	Isoastilbin has anti-acne and tyrosinase inhibition properties.
TN2025	Oxyresveratrol 2-O-beta-D-glucopyranoside	Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
TN1705	Glycyrrhisoflavone	Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
TN1804	Isosilybin A	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (...
TN1832	Kanzonol C	Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sh...
TN1840	Kurarinol	Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts vary...
T4S1658	Benzoyloxypeoniflorin	Benzoyloxypeoniflorin is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood co...
T10664	Calcium 2-oxoglutarate	Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
T2S0799	Noroxyhydrastinine	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein lev...
TC0017	Haplopine	Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the ...
TN2672	2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran	2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2...
TN2923	3'-Deoxy-4-O-methylsappanol	3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4.
TMA0593	Broussoflavonol F	Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggreg...
TN3540	Broussonin C	Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
TN3545	Buddlenoid A	Buddlenoid A shows high inhibition of mushroom tyrosinase.
TN3644	Chlorophorin	Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values o...
TN3753	Dalbergioidin	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyce...
TN3882	Dodoviscin A	Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isob...
TN4117	GB 1a	GB 1a shows potential in vitro antioxidant activities.
TN4148	Glyasperin C	Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candida...
TN4179	Haginin A	Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB acti...
TN4279	Isoderrone	Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, su...
TN4580	Morachalcone A	Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 ...
TN4642	Neorauflavane	Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin conten...
TMA2563	Pedalitin	Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl ro...
TN5117	Taxiphyllin	Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity agains...
TN5119	Taxoquinone	Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foo...
TN5153	Torilin	Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linoleni...
TMA0003	Trans-caffeic acid	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 an...
TN1545	D-Tyrosine	D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine inhibits biofilm formati...