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Proteases/Proteasome Tyrosinase

Tyrosinase

Cat No. product name
T0314 Hexylresorcinol Hexylresorcinol is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T0357 Potassium iodide Potassium iodide is used as the treatment of overactive thyroid and as protection of the thyroid gland from the influences of radiation from swallowed or inhale...
T0473 Arbutin Arbutin(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent th...
T0759 Monobenzone Monobenzone is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone is by mea...
T1188 Mizoribine Mizoribine belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T1210 Sodium etidronate Etidronate Disodium is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, et...
T1738 Taxifolin Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
T3403 Glabridin Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction,through regulating the synthesis and activity of iNOS under high-gluc...
T3737 Hydroumbellic acid Hydroumbellic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid. It i...
T3827 Rhein-8-glucoside calcium salt Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
T3923 Calycosin Calycosin acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 fami...
T4185 lavendustin C Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
T6463 Deoxyarbutin DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.
T4182 lavendustin B Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gr...
T4291 (+)-Isocorydine hydrochloride (+)-Isocorydine is a eukaryote protein kinases Inhibitor.
T2P2923 Stearic acid 1. Stearic Acid can reduce metastatic tumor burden. 2. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocyte...
T3S1068 Oxyresveratrol 1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive g...
T3S1612 kuwanon G 1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment fo...
TCS2170 Acetylhydroquinone 1. 2,5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JN...
T7052 Gnetol Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly su...
T5552 Methyl cinnamate Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
T5755 Aloesin Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first...
T7125 4-Butylresorcinol 4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
T5985 Glycolic acid Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
T7438 3,5-Dimethoxyphenol 3,5-Dimethoxyphenol as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.
T7714 Temocapil Temocapril is an inhibitor of tyrosine kinase.
T4183 lavendustin A lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
T6S1597 Mulberroside A 1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycos...
T3382 Wilforlide A Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. High-dose wilforlide A has obvious anti-inflammatory effect,...
T0666 4-Chlorosalicylic acid 4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
T8087 Tropolone Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
TN1314 6-Hydroxykaempferol 6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TN1325 6-Prenylnaringenin 6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin.
TN1690 Glabrene Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likel...
TN1928 Methyl rosmarinate Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteina...
TN1958 Mulberroside F Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity th...
TN2026 Oxyresveratrol 3'-O-beta-D-glucopyranoside Oxyresveratrol-3'-O-beta-D-glucopyranoside shows tyrosinase inhibitory activity, it may be a potential candidate as skin-whitening agents without posing any ser...
TN2078 Pinocembrin chalcone Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic...
TN2148 Retusin Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well...
TN2280 Trametenolic acid Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and...
TN2288 Uralenol Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as ...
TN2303 Viscumneoside III Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics.
TN1772 Isoastilbin Isoastilbin has anti-acne and tyrosinase inhibition properties.
TN2025 Oxyresveratrol 2-O-beta-D-glucopyranoside Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
TN1705 Glycyrrhisoflavone Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
TN1804 Isosilybin A Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (...
TN1832 Kanzonol C Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sh...
TN1840 Kurarinol Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts vary...
T4S1658 Benzoyloxypeoniflorin Benzoyloxypeoniflorin is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood co...
T10664 Calcium 2-oxoglutarate Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
Hexylresorcinol
T0314CAS 136-77-6
Hexylresorcinol is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
Potassium iodide
T0357CAS 7681-11-0
Potassium iodide is used as the treatment of overactive thyroid and as protection of the thyroid gland from the influences of radiation from swallowed or inhale...
Arbutin
T0473CAS 497-76-7
Arbutin(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent th...
Monobenzone
T0759CAS 103-16-2
Monobenzone is a Depigmenting Agent. The mechanism of action of monobenzone is as a Melanin Synthesis Inhibitor. The physiologic effect of monobenzone is by mea...
Mizoribine
T1188CAS 50924-49-7
Mizoribine belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
Sodium etidronate
T1210CAS 7414-83-7
Etidronate Disodium is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, et...
Taxifolin
T1738CAS 480-18-2
Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
Glabridin
T3403CAS 59870-68-7
Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction,through regulating the synthesis and activity of iNOS under high-gluc...
Hydroumbellic acid
T3737CAS 5631-68-5
Hydroumbellic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid. It i...
Rhein-8-glucoside calcium salt
T3827CAS 113443-70-2
Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
Calycosin
T3923CAS 20575-57-9
Calycosin acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 fami...
lavendustin C
T4185CAS 125697-93-0
Lavendustin C is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
Deoxyarbutin
T6463CAS 53936-56-4
DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.
lavendustin B
T4182CAS 125697-91-8
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived gr...
(+)-Isocorydine hydrochloride
T4291CAS 13552-72-2
(+)-Isocorydine is a eukaryote protein kinases Inhibitor.
Stearic acid
T2P2923CAS 57-11-4
1. Stearic Acid can reduce metastatic tumor burden. 2. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocyte...
Oxyresveratrol
T3S1068CAS 29700-22-9
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive g...
kuwanon G
T3S1612CAS 75629-19-5
1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment fo...
Acetylhydroquinone
TCS2170CAS 490-78-8
1. 2,5-Dihydroxyacetophenone possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JN...
Gnetol
T7052CAS 86361-55-9
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly su...
Methyl cinnamate
T5552CAS 103-26-4
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
Aloesin
T5755CAS 30861-27-9
Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first...
4-Butylresorcinol
T7125CAS 18979-61-8
4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
Glycolic acid
T5985CAS 79-14-1
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
3,5-Dimethoxyphenol
T7438CAS 500-99-2
3,5-Dimethoxyphenol as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.
Temocapil
T7714CAS 111902-57-9
Temocapril is an inhibitor of tyrosine kinase.
lavendustin A
T4183CAS 125697-92-9
lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
Mulberroside A
T6S1597CAS 102841-42-9
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycos...
Wilforlide A
T3382CAS 84104-71-2
Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. High-dose wilforlide A has obvious anti-inflammatory effect,...
4-Chlorosalicylic acid
T0666CAS 5106-98-9
4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
Tropolone
T8087CAS 533-75-5
Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion
6-Hydroxykaempferol
TN1314CAS 4324-55-4
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
6-Prenylnaringenin
TN1325CAS 68236-13-5
6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin.
Glabrene
TN1690CAS 60008-03-9
Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likel...
Methyl rosmarinate
TN1928CAS 99353-00-1
Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteina...
Mulberroside F
TN1958CAS 193483-95-3
Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity th...
Oxyresveratrol 3'-O-beta-D-glucopyranoside
TN2026CAS 144525-40-6
Oxyresveratrol-3'-O-beta-D-glucopyranoside shows tyrosinase inhibitory activity, it may be a potential candidate as skin-whitening agents without posing any ser...
Pinocembrin chalcone
TN2078CAS 4197-97-1
Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic...
Retusin
TN2148CAS 1245-15-4
Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well...
Trametenolic acid
TN2280CAS 24160-36-9
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and...
Uralenol
TN2288CAS 139163-15-8
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as ...
Viscumneoside III
TN2303CAS 118985-27-6
Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics.
Isoastilbin
TN1772CAS 54081-48-0
Isoastilbin has anti-acne and tyrosinase inhibition properties.
Oxyresveratrol 2-O-beta-D-glucopyranoside
TN2025CAS 392274-22-5
Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
Glycyrrhisoflavone
TN1705CAS 116709-70-7
Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase.
Isosilybin A
TN1804CAS 142796-21-2
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (...
Kanzonol C
TN1832CAS 151135-82-9
Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sh...
Kurarinol
TN1840CAS 855746-98-4
Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts vary...
Benzoyloxypeoniflorin
T4S1658CAS 72896-40-3
Benzoyloxypeoniflorin is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood co...
Calcium 2-oxoglutarate
T10664CAS 71686-01-6
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).