Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.

Cat. No.	Product name	CAS No.	Purity
TN2923	3'-Deoxy-4-O-methylsappanol	112408-68-1	98%
TN2923	3'-Deoxy-4-O-methylsappanol shows moderate cytotoxicities against cultured human melanoma HMV-II cells with the IC50 value of 872.0 uM ± 2.4.
TN3545	Buddlenoid A	142750-32-1	98%
TN3545	Buddlenoid A shows high inhibition of mushroom tyrosinase.
T60278	Tyrosinase-IN-2	180864-33-9	98%
T60278	Tyrosinase-IN-2 (compound 67) is a potent tyrosinase inhibitor. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalyt...
TN1314	6-Hydroxykaempferol	4324-55-4	98%
TN1314	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TN2280	Trametenolic acid	24160-36-9	98%
TN2280	Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
TN1832	Kanzonol C	151135-82-9	98%
TN1832	Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it sho...
T15204	EHT 1610	1425945-60-3	98%
T15204	EHT 1610 is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, r...
TN1690	Glabrene	60008-03-9	98%
TN1690	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely t...
TN5119	Taxoquinone	21764-41-0	98%
TN5119	Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important food...
TN4279	Isoderrone	121747-89-5	98%
TN4279	Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, sugge...
TMA0593	Broussoflavonol F	162558-94-3	98%
TMA0593	Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggrega...
TN2303	Viscumneoside III	118985-27-6	98%
TN2303	Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics.
TN4179	Haginin A	74174-29-1	98%
TN4179	Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...
TN4642	Neorauflavane	53734-74-0	98%
TN4642	Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content...
TN3882	Dodoviscin A	1372527-25-7	98%
TN3882	Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
T2S0799	Noroxyhydrastinine	21796-14-5	98%
T2S0799	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein leve...
TN2025	Oxyresveratrol 2-O-β-D-glucopyranoside	392274-22-5	98%
TN2025	Oxyresveratrol-2-O-beta-D-glucopyranoside shows better tyrosinase inhibitory activities than kojic acid.
TN4148	Glyasperin C	142474-53-1	98%
TN4148	Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidat...
TN2288	Uralenol	139163-15-8	98%
TN2288	Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
TMA0003	Trans-caffeic acid	501-16-6	98%
TMA0003	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...