T77580 |
IK-930
|
2563892-44-2
|
98%
|
|
IK-930 is an orally active TEAD inhibitor (EC50 < 0.1 µM) with potent potency.
|
T60148 |
MSC-4106
|
2738542-58-8
|
98%
|
|
MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and exhibits inhibitory effect on NCI-H22...
|
TP2160L1 |
YAP-TEAD-IN-1 acetate
|
TP2160L1
|
98%
|
|
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.
|
T64342 |
DC-TEADin02
|
2380228-45-3
|
98%
|
|
DC-TEADin02 is an inhibitor of TEAD auto palmitoylation (IC50 = 197 nM). DC-TEADin02 can be in studies about development, regeneration, and tissue homeostasis.
|
T60218 |
YAP/TAZ inhibitor-2
|
2762617-31-0
|
98%
|
|
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC 50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative and antitumor ...
|
T9566 |
PY-60
|
2765218-56-0
|
98%
|
|
PY-60 potently activates YAP transcriptional activities targeting annexin A2 (Kd = 1.4 µM). PY-60 activates a proproliferative, YAP-dependent transcriptional pro...
|
T22372 |
MYF-01-37
|
2416417-65-5
|
98%
|
|
MYF-01-37 is a novel covalent TEAD inhibitor.
|
T67872 |
VT104
|
2417718-25-1
|
98%
|
|
VT104 is a potent YAP/TAZ inhibitor with oral activity that can be used in cancer research. VT104 prevents palmitylation of endogenous TEAD1 and TEAD3 proteins.
|
T3050 |
ML-7 hydrochloride
|
110448-33-4
|
98%
|
|
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-musc...
|
T1477 |
AICAR
|
2627-69-2
|
98%
|
|
Acadesine is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating othe...
|
T35545 |
VT107
|
2417718-63-7
|
98%
|
|
VT107 is a potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer[1].
|
T9053 |
Lats-IN-1
|
1424635-83-5
|
98%
|
|
Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
|
T3112 |
Verteporfin
|
129497-78-5
|
98%
|
|
Verteporfin, a benzoporphyrin derivative monoacid ring A, can inhibit the activity of YAP.
|
T8421 |
TED-347
|
2378626-29-8
|
98%
|
|
TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
|
T69760 |
TT-10
|
2230640-94-3
|
98%
|
|
TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart...
|