T64342 |
DC-TEADin02
|
2380228-45-3
|
98%
|
|
DC-TEADin02 is an inhibitor of TEAD auto palmitoylation (IC50 = 197 nM). DC-TEADin02 can be in studies about development, regeneration, and tissue homeostasis.
|
TP2160L1 |
YAP-TEAD-IN-1 acetate
|
|
98.11%
|
|
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.
|
T60218 |
YAP/TAZ inhibitor-2
|
2762617-31-0
|
98.84%
|
|
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/T...
|
T9566 |
PY-60
|
|
98.86%
|
|
PY-60 potently activates YAP transcriptional activities targeting annexin A2 (Kd = 1.4 µM). PY-60 activates a proproliferative, YAP-dependent transcriptional pro...
|
T22372 |
MYF-01-37
|
2416417-65-5
|
99.46%
|
|
MYF-01-37 is a novel covalent TEAD inhibitor.
|
T3050 |
ML-7 hydrochloride
|
110448-33-4
|
99.61%
|
|
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-musc...
|
T1477 |
AICAR
|
2627-69-2
|
99.71%
|
|
Acadesine is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating othe...
|
T3112 |
Verteporfin
|
129497-78-5
|
99.82%
|
|
Verteporfin, a benzoporphyrin derivative monoacid ring A, can inhibit the activity of YAP.
|
T9053 |
Lats-IN-1
|
1424635-83-5
|
99.82%
|
|
Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.
|
T8421 |
TED-347
|
2378626-29-8
|
99.91%
|
|
TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
|