Acyltransferase

Acyltransferase is a type of transferase enzyme that acts upon acyl groups.

Cat. No.	Product name	CAS No.	Purity
T6937	PF-04620110	1109276-89-2	98%
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
T12426	PF-06424439	1469284-78-3	98%
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
T13373	YM17E	124900-72-7	98%
YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.
T12767	RP 70676	136609-26-2	98%
RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
T23521	VULM 1457	228544-65-8	98%
Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor
T10035	10,12-Tricosadiynoic acid	66990-30-5
10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It can treat the high-fat diet- or obesity-induced met...
T5544	2-Furoic acid	88-14-2	100%
2-Furoic acid, an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessiv...
T16409	OSMI-1	1681056-61-0	96.79%
OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked...
T6365	A 922500	959122-11-3	97.34%
A922500 is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferases, hERG, and a panel o...
T8236	RHC 80267	83654-05-1	98%
RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 µM in canine platelets)
T8314	RP-64477	135239-65-5	99.16%
RP64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.
T0504	Cyclandelate	456-59-7	99.21%
Cyclandelate, a direct-acting smooth muscle relaxant, is used to dilate blood vessels.
T12225L	Nevanimibe hydrochloride	133825-81-7	99.25%
Nevanimibe hydrochloride is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).
T3342	Xanthohumol	6754-58-1	99.36%
Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated...
T22665	PD 128042	114289-47-3	99.44%
acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor
TN1691	Glabrol	59870-65-4	99.72%
Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
T12425	PF-06424439 methanesulfonate	1469284-79-4	99.79%
PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor(IC50 of 14 nM)[1]. PF-06424439 m...
T11733	K-604 dihydrochloride	217094-32-1	99.88%
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.
T4681	T863	701232-20-4	99.88%
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
T2753	Avasimibe	166518-60-1	99.91%
Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the ar...

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T6937

PF-04620110

1109276-89-2

98%

PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.

T12426

PF-06424439

1469284-78-3

98%

PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).

T13373

YM17E

124900-72-7

98%

YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.

T12767

RP 70676

136609-26-2

98%

RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).

T23521

VULM 1457

228544-65-8

98%

Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor

T10035

10,12-Tricosadiynoic acid

66990-30-5

10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It can treat the high-fat diet- or obesity-induced met...

T5544

2-Furoic acid

88-14-2

100%

2-Furoic acid, an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessiv...

T16409

OSMI-1

1681056-61-0

96.79%

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked...

T6365

A 922500

959122-11-3

97.34%

A922500 is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferases, hERG, and a panel o...

T8236

RHC 80267

83654-05-1

98%

RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 µM in canine platelets)

T8314

RP-64477

135239-65-5

99.16%

RP64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.

T0504

Cyclandelate

456-59-7

99.21%

Cyclandelate, a direct-acting smooth muscle relaxant, is used to dilate blood vessels.

T12225L

Nevanimibe hydrochloride

133825-81-7

99.25%

Nevanimibe hydrochloride is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).

T3342

Xanthohumol

6754-58-1

99.36%

Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated...

T22665

PD 128042

114289-47-3

99.44%

acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor

TN1691

Glabrol

59870-65-4

99.72%

Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.

T12425

PF-06424439 methanesulfonate

1469284-79-4

99.79%

PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor(IC50 of 14 nM)[1]. PF-06424439 m...

T11733

K-604 dihydrochloride

217094-32-1

99.88%

K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.

T4681

T863

701232-20-4

99.88%

T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...

T2753

Avasimibe

166518-60-1

99.91%

Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the ar...