T79764 |
PF-07202954
|
2639372-47-5
|
98%
|
|
PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against human...
|
T82848 |
BMS-986172
|
1808258-99-2
|
98%
|
|
BMS-986172 is an orally active, highly selective inhibitor of MGAT2, demonstrating inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM ...
|
T12426 |
PF-06424439
|
1469284-78-3
|
98%
|
|
PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of 14 nM).
|
T29329 |
24-Methylenecholesterol
|
474-63-5
|
98%
|
|
24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.
|
T16409 |
OSMI-1
|
1681056-61-0
|
99.83%
|
|
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qua...
|
T6937 |
PF-04620110
|
1109276-89-2
|
99.82%
|
|
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
|
T12425 |
PF-06424439 methanesulfonate
|
1469284-79-4
|
99.79%
|
|
PF-06424439 methanesulfonate, an orally administered, potent, and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14...
|
T12797 |
RU-SKI 43
|
1043797-53-0
|
99.78%
|
|
RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM.RU-SKI 43 has anticancer activity and is a potential compoun...
|
TN1691 |
Glabrol
|
59870-65-4
|
99.72%
|
|
Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
|
T23550 |
YM-750
|
138046-43-2
|
99.63%
|
|
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of ch...
|
T25651 |
Lecimibide
|
130804-35-2
|
99.45%
|
|
Lecimibide (DuP 128) is a potent and selective inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT), which can be used to study diseases due to high ...
|
T22665 |
PD 128042
|
114289-47-3
|
99.44%
|
|
PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhi...
|
T12225L |
Nevanimibe hydrochloride
|
133825-81-7
|
99.25%
|
|
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 o...
|
T25635 |
Lateritin
|
65454-13-9
|
99.23%
|
|
Lateritin (Bassiatin) is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor from the mycelial cake of Gibberella later...
|
T3342 |
Xanthohumol
|
6754-58-1
|
99.18%
|
|
Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated...
|
T8314 |
RP-64477
|
135239-65-5
|
99.16%
|
|
RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.
|
T12767 |
RP 70676
|
136609-26-2
|
98.89%
|
|
RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
|
T2753 |
Avasimibe
|
166518-60-1
|
98.77%
|
|
Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol depositi...
|
T27245L |
Eflucimibe
|
202340-45-2
|
98.56%
|
|
Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders...
|
T31611 |
Eldacimibe
|
141993-70-6
|
98.30%
|
|
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hy...
|