T14142 |
AGL-2263
|
638213-98-6
|
98%
|
|
AGL-2263 is a blocker of insulin receptor (IR)
|
TN4675 |
Nortrachelogenin
|
34444-37-6
|
98%
|
|
Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth ...
|
T6003 |
GSK1904529A
|
1089283-49-7
|
98%
|
|
GSK1904529A is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
|
T2349 |
BMS-754807
|
1001350-96-4
|
98%
|
|
Dual IGF-1R/InsR Inhibitor BMS-754807 is an oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine ...
|
T13564 |
AZ7550
|
1421373-99-0
|
98%
|
|
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
T9980 |
AVJ16
|
|
98%
|
|
AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.
|
TN7108 |
Urolithin C
|
165393-06-6
|
98%
|
|
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
|
T24398 |
Lenaldekar
|
418800-15-4
|
98%
|
|
Lenaldekar is a T-cell expansion and autoimmune encephalomyelitis inhibitor.
|
T21761 |
HNMPA
|
132541-52-7
|
98%
|
|
HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin recep...
|
TP1125 |
Insulin(cattle)
|
11070-73-8
|
|
|
Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells。It has often been used as growth supp...
|
T9030 |
SU4984
|
186610-89-9
|
100%
|
|
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
|
TP2209L |
Xenin 8 acetate
|
|
95.54%
|
|
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family. Xenin 8 acetate augments Arginine-induced insulin release (by 40%)...
|
T13564L |
AZ7550 hydrochloride
|
2309762-40-9
|
97.07%
|
|
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
|
T3059 |
ALK-IN-1
|
1197958-12-5
|
97.66%
|
|
AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. P...
|
T6S1487 |
Ginsenoside Rg5
|
186763-78-0
|
98%
|
|
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production a...
|
T2755 |
Rhoifolin
|
17306-46-6
|
98.11%
|
|
Rhoifolin is extracted from Turpinia arguya Seem dried leaves.
|
T2642 |
PD173074
|
219580-11-7
|
98.21%
|
|
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for ...
|
TP2018L |
GIP (human) acetate
|
|
98.65%
|
|
GIP (human) acetate is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP (human) acetate plays a vital role...
|
T3079 |
GSK1838705A
|
1116235-97-2
|
98.89%
|
|
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to ...
|
T17267 |
XL228
|
898280-07-4
|
98.92%
|
|
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).
|