Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.

Cyclohexylphenylketone (AI311009) can be used as a photo-initiator and a spectrophotometric determination of benzophenone.

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can cause chemical/occupational leukoderma. 2. Raspberry ketone is marketed on the Internet as a food supplement.

Cyclopentyl phenyl ketone (Benzoylcyclopentane) is used for the prevention and treatment of traumatic stress.

Dilinoleyl Ketone (Bis(linoleyl) ketone) is a lipid membrane that is a potential carrier of nucleic acids.

Dicyclohexyl ketone (Cyclohexane ketone) is a vulcanization accelerator.

NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.

Tanshinone IIA (Tanshinone B)(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.

Acetophenone (Phenylethanone) is used in chemical synthesis and as a fragrance.

Watermelon ketone (7-Methyl-2H-1,5-benzodioxepin-3(4H)-one) is a fragrance compound, with a special odorant. It has been widely used in the fragrance industry.

Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 phosphorylation.

2-Acetylthiazole (2-Acetylthiazole;2 Acetylthiazole) is used in the preparation of chiral alcohols, triazolothiazoles, it is also used in aldol condensation reactions.

3-Benzoylpyridine (Phenyl 3-pyridyl ketone) is a decomposition product of HGG-12 which is the soman antidote.

BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrate, blood Na+, blood glucose levels and blood creatinine levels after oral administration in mice. BD-AcAc 2 can partly prevent muscle weakness in septic mice. BD-AcAc 2 exhibits potential to improve endurance and exercise performance in animal body. BD-AcAc 2 can also be used to research diabetes or Parkinson’s disease.

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid. It is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Moreover, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. Given its diverse applications, AACOCF3 holds promise for cardiovascular disease research.

Naginata ketone is a natural product for research related to life sciences. The catalog number is TN5853 and the CAS number is 6138-88-1.

Ezetimibe, a compound known as a Niemann-Pick C1-like1 (NPC1L1) inhibitor and a potent Nrf2 activator, effectively inhibits cholesterol absorption. Additionally, Ezetimibe ketone (EZM-K) represents a phase-I metabolite of Ezetimibe.

Lycernuic ketone B is a useful organic compound for research related to life sciences and the catalog number is T124838.

Divinyl ketone is a kind of high reactivity, easy polymerization of multifunctional cyclization reagent.

Perilla ketone is a naturally occurring xenobiotic compound that undergoes activation by pulmonary P450 cytochrome enzymes within the lung. This activation leads to the manifestation of severe pulmonary damage and the development of diffuse pulmonary edema.

Windaus ketone functions as a vitamin D (VD) synthesis inhibitor.

Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.

Cyclopropyl methyl ketone can be used in the preparation of homoallylic alcohols.

Lysine chloromethyl ketone is an affinity label for peptides.

Raspberry ketone glucoside is a natural product in raspberry fruit, has lasting effects for the inhibition of melanogenesis and various melanogenic factors after the degradation in the skin.

Montelukast methyl ketone is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhibits an inhibitory effect on IFN-γ activities.

Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) functions as a cysteine protease inhibitor and has been shown to impede SARS infection. Furthermore, it affords protection to mice when challenged with T. crassiceps [1] [2].

Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.

2'-Hydroxyacetophenone (o-Hydroxyacetophenone) is a phenolic compound used in the synthesis of potential anti-myobacterial and anticancer agents.

Deoxybenzoin (2-Phenylacetophenone) is used to target immune sensors and xanthine oxidase. It is used for the treatment of gout.

Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. Benzylacetone has a strong and reversible anti-mushroom tyrosinase effect, with IC50 values of 2.8 mM and 0.6 mM for monophenolase and biphenolase effects, respectively.

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2]

2-Acetonaphthone (beta-Naphthyl methyl ketone) is a fragrance, anticonvulsant, and antimicrobial agent. It has an onion type flavor and a sulfurous type odor.

p-Phenylpropiophenone is anticipated as an energy sink.

Capriphenone is an intermediate for antituberculous, antiviral, antibacterial, and antifungal products.

4-Methyl-1-phenyl-2-pentanone (Benzyl isobutyl ketone) is a volatile flavor that is used as a food additive.

Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.

3-Acetyl-2,5-dimethylfuran is a flavoring agent, it has a nutty type flavor and a musty type odor.

SL-01 is an oral derivative of gemcitabine. SL-01 inhibited human breast cancer growth through the induction of apoptosis. SL-01 inhibited human cancer growth more potently than gemcitabine.

(S,S)-BD-AcAc 2 ((S,S)-Ketone Ester), an (S,S)-enantiomer of BD-AcAc 2, increases AcAc and acetone levels, inducing sustained ketosis and significantly delaying seizures associated with central nervous system oxygen toxicity (CNS-OT).

Decanophenone, 10-fluoro- is a biochemical.

3-Oxo-3-phenylpropene is an active-site directed irreversible inhibitor of hydroxynitrile lyase.

Octanophenone can be analyzed by reverse phase (RP) HPLC method with simple conditions. The phosphoric acid needs to be replaced with formic acid for Mass-Spec (MS) compatible applications. For fast UPLC applications, smaller 3 µm particles columns is av

1-(4-Pyridinyl)-1-propanone is chemical used for drug synthesis

2-Nonanone is a flavor and fragrance agent with a fruity type odor and a cheesy type flavor.

2-Acetylfluorene is a product used for proteomics research.

Isophorone is a clear liquid that smells like peppermint. It can be dissolved in water and evaporates somewhat faster than water.

3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical pa