T0677 |
Chlorothiazide
|
58-94-6
|
95.42%
|
|
Chlorothiazide is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
|
T0515 |
Tioxolone
|
4991-65-5
|
95.9%
|
|
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
|
T4S2354 |
Dimethylfraxetin
|
6035-49-0
|
98%
|
|
Dimethylfraxetin is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
|
T6781 |
Benzenesulfonamide
|
98-10-2
|
98%
|
|
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
|
T0738 |
Urea
|
57-13-6
|
98%
|
|
Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
|
T36758 |
CAIX Inhibitor S4
|
1330061-67-0
|
98.35%
|
|
CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
|
T21294 |
Polmacoxib
|
301692-76-2
|
98.49%
|
|
Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
|
T2S0357 |
6-Hydroxycoumarin
|
6093-68-1
|
98.5%
|
|
6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
|
T6469 |
Dichlorphenamide
|
120-97-8
|
98.51%
|
|
Dichlorphenamide is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
|
T0114 |
Trichlormethiazide
|
133-67-5
|
99.32%
|
|
Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appear...
|
T9323 |
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
|
654-62-6
|
99.34%
|
|
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
|
T2134 |
Dorzolamide hydrochloride
|
130693-82-2
|
99.48%
|
|
Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid co...
|
T0142 |
Brinzolamide
|
138890-62-7
|
99.5%
|
|
Brinzolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
|
T1026 |
Mafenide hydrochloride
|
138-37-4
|
99.53%
|
|
Mafenide hydrochloride is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
|
T2017 |
U-104
|
178606-66-1
|
99.6%
|
|
U-104 is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
|
T0813 |
Acetazolamide
|
59-66-5
|
99.61%
|
|
Acetazolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of ac...
|
T5012 |
Ethoxzolamide
|
452-35-7
|
99.62%
|
|
Ethoxzolamide is a carbonic anhydrase inhibitor.
|
T1999 |
Taselisib
|
1282512-48-4
|
99.62%
|
|
Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity....
|
T1409 |
Methocarbamol
|
532-03-6
|
99.75%
|
|
Methocarbamol is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of muscu...
|