Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.

Cat. No.	Product name	CAS No.	Purity
T25372	EMD57033	147527-31-9	98%
T25372	EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
T68136	5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)-	133276-52-5	98%
T68136	5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)- shows activity against Carbonic anhydrase and Cyclooxygenase 2.
T0037	Halazone	80-13-7	98%
T0037	Halazone is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
TN6707	Methyl 2,4-dihydroxybenzoate	2150-47-2	98%
TN6707	Methyl 2,4-dihydroxybenzoate is a natural product.
T0267	Zonisamide	68291-97-4	98%
T0267	Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...
T8827	EMAC10101d	2561476-24-0	98%
T8827	compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an i...
T16960	Sultiame	61-56-3	98%
T16960	Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.
T2616	PIK-93	593960-11-3	98%
T2616	PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
T6S0221	Eriocitrin	13463-28-0	98%
T6S0221	1. Eriocitrin is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in...
T0465	Ellagic acid	476-66-4	98%
T0465	Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
T67774	Compound CDy9	952306-80-8	98%
T67774	Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.
T2530	Levosimendan	141505-33-1	98%
T2530	Levosimendan is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calci...
T1999	Taselisib	1282512-48-4	98%
T1999	Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity....
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide	654-62-6	98%
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
T4321	Indisulam	165668-41-7	98%
T4321	Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and ...
T2S0357	6-Hydroxycoumarin	6093-68-1	98%
T2S0357	6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
T21294	Polmacoxib	301692-76-2	98%
T21294	Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
T36758	CAIX Inhibitor S4	1330061-67-0	98%
T36758	CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
T4S2354	Dimethylfraxetin	6035-49-0	98%
T4S2354	Dimethylfraxetin is a Carbonic anhydrase inhibitor（Ki：0.0097 μM）
T0738	Urea	57-13-6	98%
T0738	Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...