Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.

Cat. No.	Product name	CAS No.	Purity
T0677	Chlorothiazide	58-94-6	95.42%
T0677	Chlorothiazide is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
T0515	Tioxolone	4991-65-5	95.9%
T0515	Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
T4S2354	Dimethylfraxetin	6035-49-0	98%
T4S2354	Dimethylfraxetin is a Carbonic anhydrase inhibitor（Ki：0.0097 μM）
T6781	Benzenesulfonamide	98-10-2	98%
T6781	Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
T0675	Topiramate	97240-79-4	98%
T0675	Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T0738	Urea	57-13-6	98%
T0738	Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
T36758	CAIX Inhibitor S4	1330061-67-0	98.35%
T36758	CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
T21294	Polmacoxib	301692-76-2	98.49%
T21294	Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
T2S0357	6-Hydroxycoumarin	6093-68-1	98.5%
T2S0357	6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
T6469	Dichlorphenamide	120-97-8	98.51%
T6469	Dichlorphenamide is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
T0114	Trichlormethiazide	133-67-5	99.32%
T0114	Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appear...
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide	654-62-6	99.34%
T9323	4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
T2134	Dorzolamide hydrochloride	130693-82-2	99.48%
T2134	Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid co...
T0142	Brinzolamide	138890-62-7	99.5%
T0142	Brinzolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
T1026	Mafenide hydrochloride	138-37-4	99.53%
T1026	Mafenide hydrochloride is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
T2017	U-104	178606-66-1	99.6%
T2017	U-104 is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
T0813	Acetazolamide	59-66-5	99.61%
T0813	Acetazolamide is a Carbonic Anhydrase Inhibitor. The mechanism of action of acetazolamide is as a Carbonic Anhydrase Inhibitor. The chemical classification of ac...
T5012	Ethoxzolamide	452-35-7	99.62%
T5012	Ethoxzolamide is a carbonic anhydrase inhibitor.
T1999	Taselisib	1282512-48-4	99.62%
T1999	Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity....
T1409	Methocarbamol	532-03-6	99.75%
T1409	Methocarbamol is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of muscu...