T25372 |
EMD57033
|
147527-31-9
|
98%
|
|
EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to pro...
|
T68136 |
5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)-
|
133276-52-5
|
98%
|
|
5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)- shows activity against Carbonic anhydrase and Cyclooxygenase 2.
|
T0037 |
Halazone
|
80-13-7
|
98%
|
|
Halazone is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
|
TN6707 |
Methyl 2,4-dihydroxybenzoate
|
2150-47-2
|
98%
|
|
Methyl 2,4-dihydroxybenzoate is a natural product.
|
T0267 |
Zonisamide
|
68291-97-4
|
98%
|
|
Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydra...
|
T8827 |
EMAC10101d
|
2561476-24-0
|
98%
|
|
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an i...
|
T16960 |
Sultiame
|
61-56-3
|
98%
|
|
Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.
|
T2616 |
PIK-93
|
593960-11-3
|
98%
|
|
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
|
T6S0221 |
Eriocitrin
|
13463-28-0
|
98%
|
|
1. Eriocitrin is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in...
|
T0465 |
Ellagic acid
|
476-66-4
|
98%
|
|
Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
|
T67774 |
Compound CDy9
|
952306-80-8
|
98%
|
|
Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.
|
T2530 |
Levosimendan
|
141505-33-1
|
98%
|
|
Levosimendan is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calci...
|
T1999 |
Taselisib
|
1282512-48-4
|
98%
|
|
Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity....
|
T9323 |
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
|
654-62-6
|
98%
|
|
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
|
T4321 |
Indisulam
|
165668-41-7
|
98%
|
|
Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and ...
|
T2S0357 |
6-Hydroxycoumarin
|
6093-68-1
|
98%
|
|
6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a hu...
|
T21294 |
Polmacoxib
|
301692-76-2
|
98%
|
|
Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant col...
|
T36758 |
CAIX Inhibitor S4
|
1330061-67-0
|
98%
|
|
CAIX Inhibitor S4 is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM...
|
T4S2354 |
Dimethylfraxetin
|
6035-49-0
|
98%
|
|
Dimethylfraxetin is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
|
T0738 |
Urea
|
57-13-6
|
98%
|
|
Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
|