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Metabolism NADPH

NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.
Cat No. product name
T0342 Carvedilol phosphate Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
T0441 Pasiniazid Pasiniazid is an anti-TB and anti-leprosy drug.
T0447 Carvedilol Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
T0809 Dicumarol Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a com...
T0816 Acetohexamide Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inw...
T1079 Metronidazole Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T1313 Nitrofurantoin Nitrofurantoin, an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inacti...
T1314 Triclosan Triclosan is an antibacterial and antifungal agent.
T1558 ResveratrolHOT Resveratrol is a polyphenolic phytoalexin with antioxidant and chemopreventive activities. It has a wide spectrum of targets including COX, SIRT, LOC, etc.
T1609 Cozymase NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and i...
T4529 ASP-9521 ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
T6391 Acetovanillone Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
T4359 VAS2870 VAS2870 is a NADPH oxidase (NOX) inhibitor.
T7149 S29434 S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
T7406 AKR1C3-IN-1 AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
T16361 Nucleocidin Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
T14151 AKR1C1-IN-1 AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
TN3806 Dehydroglyasperin C Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemo...
Carvedilol phosphate
T0342CAS 610309-89-2
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
Pasiniazid
T0441CAS 2066-89-9
Pasiniazid is an anti-TB and anti-leprosy drug.
Carvedilol
T0447CAS 72956-09-3
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
Dicumarol
T0809CAS 66-76-2
Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a com...
Acetohexamide
T0816CAS 968-81-0
Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inw...
Metronidazole
T1079CAS 443-48-1
Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
Nitrofurantoin
T1313CAS 67-20-9
Nitrofurantoin, an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inacti...
Triclosan
T1314CAS 3380-34-5
Triclosan is an antibacterial and antifungal agent.
Resveratrol HOT
T1558CAS 501-36-0
Resveratrol is a polyphenolic phytoalexin with antioxidant and chemopreventive activities. It has a wide spectrum of targets including COX, SIRT, LOC, etc.
Cozymase
T1609CAS 53-84-9
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and i...
ASP-9521
T4529CAS 1126084-37-4
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
Acetovanillone
T6391CAS 498-02-2
Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
VAS2870
T4359CAS 722456-31-7
VAS2870 is a NADPH oxidase (NOX) inhibitor.
S29434
T7149CAS 874484-20-5
S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
AKR1C3-IN-1
T7406CAS 327092-81-9
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
Nucleocidin
T16361CAS 24751-69-7
Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
AKR1C1-IN-1
T14151CAS 4906-68-7
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
Dehydroglyasperin C
TN3806CAS 199331-35-6
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemo...