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NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.
Cat No. product name
TN2126 Quercetin-3-O-glucose-6''-acetate Quercetin-3-O-glucose-6''-acetate 是 NADPH 氧化酶的抑制剂。 Quercetin-3-O-glucose-6''-acetate 具有抗氧化活性。
T0342 Carvedilol phosphate hemihydrate Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intri...
T8408 GKT136901 GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
T8107 GLX351322 GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T15433 GSK2795039 GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
T6099 Setanaxib GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T10353 APX-115 free base APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox...
T6391 Apocynin Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
T7191 Diphenyleneiodonium chloride Diphenyleneiodonium chloride(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bacte...
T7149 S29434 S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
T1079 Metronidazole Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T16342 KL1333 KL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subseque...
T0809 Dicoumarol Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competiti...
T1609 NAD+ NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is...
T1558 Resveratrol Resveratrol is a polyphenolic phytoalexin with antioxidant and chemopreventive activities. It has a wide spectrum of targets including COX, SIRT, LOC, etc.
T1314 Triclosan Triclosan is an antibacterial and antifungal agent.
T7406 AKR1C3-IN-1 AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
T7374 2-HBA 2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
T0441 Pasiniazid Pasiniazid is an anti-TB and anti-leprosy drug.
T0816 Acetohexamide Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwar...
TN3806 Dehydroglyasperin C Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
T4359 VAS2870 VAS2870 is a NADPH oxidase (NOX) inhibitor.
T4529 ASP-9521 ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
T16361 Nucleocidin Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
T14151 AKR1C1-IN-1 AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
Quercetin-3-O-glucose-6''-acetate
TN2126
Quercetin-3-O-glucose-6''-acetate 是 NADPH 氧化酶的抑制剂。 Quercetin-3-O-glucose-6''-acetate 具有抗氧化活性。
Carvedilol phosphate hemihydrate
T0342
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intri...
GKT136901
T8408
GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
GLX351322
T8107
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
GSK2795039
T15433
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2...
Setanaxib
T6099
GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
APX-115 free base
T10353
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, an...
Apocynin
T6391
Apocynin is a specific NADPH-oxidase inhibitor (IC50: 10 μM).
Diphenyleneiodonium chloride
T7191
Diphenyleneiodonium chloride(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bact...
S29434
T7149
S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).
Metronidazole
T1079
Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
KL1333
T16342
KL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subseque...
Dicoumarol
T0809
Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competiti...
NAD+
T1609
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is...
Resveratrol
T1558
Resveratrol is a polyphenolic phytoalexin with antioxidant and chemopreventive activities. It has a wide spectrum of targets including COX, SIRT, LOC, etc.
Triclosan
T1314
Triclosan is an antibacterial and antifungal agent.
AKR1C3-IN-1
T7406
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
2-HBA
T7374
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
Pasiniazid
T0441
Pasiniazid is an anti-TB and anti-leprosy drug.
Acetohexamide
T0816
Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwar...
Dehydroglyasperin C
TN3806
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
VAS2870
T4359
VAS2870 is a NADPH oxidase (NOX) inhibitor.
ASP-9521
T4529
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
Nucleocidin
T16361
Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
AKR1C1-IN-1
T14151
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).