1-β-d-glucosylsphingadienine (d-18:2 (4e,8e))

D-Luciferin potassium (D-Luciferin K Salt) is a popular bioluminescent substrate of luciferase in the presence of ATP.

D-Luciferin Sodium is a heterocyclic light-emitting compound and natural ligand for luciferase used to detect cell activity. The salt form of luciferin dissolves in water or other typical buffers.

2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins.

5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.

6-Ethyl-7-hydroxy-4-methylchromen-2-one is a fluorescent dye.

8-(4-iodophenyl)-1,3,5,7-tetramethyl BODIPY is a novel BODIPY fluorescent dye for the treatment of cytotoxicity.

4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.

Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) serves as a chromogenic substrate for peroxidase enzymes, reacting to form a purple indamine dye in the presence of peroxidases and peroxides [1].

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan serves as a precolumn fluorescence derivatization reagent.

D-Ala-Lys-AMCA TFA is a proton-coupled oligopeptide transporter 1 (PEPT1) substrate characterized by its emission of blue fluorescence. It has been demonstrated through fluorescence analysis that this compound can be transported into liver cancer cells and Caco-2 cells. Its utility extends to the characterization of PEPT1-specific substrates or inhibitors [1] [2].

Fluorescein Di-β-D-Glucuronide, a fluorescent probe, enables non-invasive imaging of intestinal bacterial β-glucuronidase activity in nude mice. This compound's utilization for both in vitro and in vivo imaging offers valuable insights into bacterial β-glucuronidase activity, thereby enhancing pharmacodynamic research on its specific inhibitors in animal models [1].

D & C Red no. 31 is an agent of dye.

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine, featuring a phosphatidylethanolamine head group, serves as a fluorescent probe to assess surface lipid oxidation in lipoproteins and plasma [1].

D-Ala-Lys-AMCA TFA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into Caco-2 cells and liver cancer cells.

6-Chloro-3-indoxyl-α-D-mannopyranoside serves as a chromogenic substrate for the enzyme α-mannosidase, producing a salmon-colored precipitate following enzymatic cleavage.

Purple-β-D-Gal, a chromogenic β-galactosidase substrate, undergoes enzymatic hydrolysis by intracellular β-galactosidase, yielding indoxyl molecules that oxidize and dimerize in situ to form water-insoluble indigo precipitates advantageous for β-galactosidase activity detection [1].

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.

N-[4-(2-Benzimidazolyl)phenyl]maleimide serves as a potent fluorescent probe featuring an excitation maximum at 315 nm and emission maximum at 360 nm, suitable for the fluorometry of thiol compounds [1].

4-(Benzyloxy)-2-nitrophenol serves as a synthetic precursor for constructing fluorescent ion indicators [1].

7-Aminoactinomycin D is a fluorescent DNA stain.

D131 is an orange indoline organic dye with an absorption maximum in solution at λ=425 nm [1] [2].

CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].

4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm. The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.

3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin serves as a pteridine-based fluorescent guanosine analogue and DNA uptake tracer utilized extensively for investigation into DNA binding and dynamics. It exhibits an absorbance peak at 350 nm and a corresponding emission peak at 430 nm [1].

Rose-β-D-Gal, a fluorescent dye, serves as a β-galactosidase substrate, producing a pink/magenta color upon reaction that facilitates the detection of β-gal activity [1] [2].

D&C Red No. 8 is a dye.

4-Nitrophenyl β-D-xylopyranoside serves as a chromogenic substrate for β-xylosidase, facilitating the assessment of enzyme activity.

4-Di-1-ASP, a styryl dye, selectively stains glioma cells within live brain tissue, facilitating microscopic analysis of cell structure, viability, and processes including proliferation, endocytosis, cytokinesis, and phagocytosis. It also allows for the observation of mitochondrial structures in living cells. The dye exhibits green fluorescence when visualized under a microscope (λ ex /λ em = 475/606 nm) [1] [2].

4-Methylumbelliferyl-β-D-galactoside (MUG) is a fluorogenic substrate for β-galactosidase (β-gal).1Hydrolysis of MUG by β-gal releases the fluorescent moiety 4-MU, which displays a pH-dependent excitation maximum of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm.2MUG has been used to detect β-gal activity in intact bacteria, yeast, and mammalian cells.1 1.Vidal-Aroca, F., Giannattasio, M., Brunelli, E., et al.One-step high-throughput assay for quantitative detection of β-galactosidase activity in intact Gram-negative bacteria, yeast, and mammalian cellsBiotechniques40(4)433-434(2006) 2.Zhi, H., Wang, J., Wang, S., et al.Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsuleJ. Spectrosc.1(1)147128(2013)

Fluorescein di-beta-D-galactopyranoside (FDG) is a fluorescent substrate for the detection of β-galactosidase in kinetoplastids and animals by flow cytometry , λex=485 nm, λem=535 nm.

8-(2-azidobenzylthio) NAD+ is a derivatized version of NAD+, a signaling molecule and enzyme cofactor, featuring an azido group (azidobenzylthio) that enables click chemistry applications.

AMCA-X, N-succinimidyl ester is an amine-reactive, UV-excitable, blue fluroscent dye.

2,5-Dioxopyrrolidin-1-yl 2-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate is a useful organic compound for research related to life sciences. The catalog number is T67683 and the CAS number is 96735-88-5.

7-(Diethylamino)-4-methyl-2H-chromen-2-one is a useful organic compound for research related to life sciences. The catalog number is T66262 and the CAS number is 91-44-1.

2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye with a nitrogen atom within its structure, which may interact with the nitrogen introduced during the amination step [1].

5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt is a useful organic compound for research related to life sciences. The catalog number is T64896 and the CAS number is 129541-41-9.

4,4'-((4-Iminocyclohexa-2,5-dien-1-ylidene)methylene)dianiline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64740 and the CAS number is 569-61-9.

D-Ala-Lys-AMCA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into Caco-2 cells and liver cancer cells.

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65277 and the CAS number is 6950-82-9.

2-(7-Methoxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T64951 and the CAS number is 62935-72-2.

8-(4-Azidophenacylthio) NAD+ is a clickable variant of the essential signaling molecule and enzyme cofactor, NAD+.

Sodium 2,6-dibromo-4-(3-(3,5-dibromo-4-hydroxy-2-methylphenyl)-2,2-dioxido-3H-benzo[d][1,2]oxathiol-3-yl)-3-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T64788 and the CAS number is 62625-32-5.

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrat (λex=362 nm , λem=445 nm).

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes with LPS or concanavalin A at concentrations of 50 to 150 µM. Utilized in ambiguous base pairing investigations within vinyl chloride-induced mutagenesis research, ε-dATP, along with its related compound ε-ATP—which exhibits an emission peak at 415 nm after being excited at 300 nm—contributes to understanding genetic alterations mechanisms.

D & C Red no. 30 is an agent of red dye.

7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. For preservation, it should be protected from light.

N-(4-(Bis(4-(diethylamino)phenyl)methylene)cyclohexa-2,5-dien-1-ylidene)-N-ethylethanaminium chloride is a useful organic compound for research related to life sciences. The catalog number is T65162 and the CAS number is 2390-59-2.

D&C Red No. 27 Aluminum Lake is a drug and cosmetic synthetic dye. The FDA lists it as a safe additive for drugs and cosmetics as per FDA standards.

2-([1,1-Biphenyl]-4-yl)-5-phenyl-1,3,4-oxadiazole is a useful organic compound for research related to life sciences. The catalog number is T66233 and the CAS number is 852-38-0.

Sodium 4-(3-(4-hydroxy-5-isopropyl-2-methylphenyl)-1,1-dioxido-3H-benzo[c][1,2]oxathiol-3-yl)-2-isopropyl-5-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T66669 and the CAS number is 62625-21-2.