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REM127 is a small molecular compound that modulates cellular calcium homeostasis and provides neuroprotection. It efficiently restores the imbalance of calcium homeostasis in cell models caused by the pathological accumulation of tau protein. Furthermore, REM127 can effectively cross the blood-brain barrier and offers therapeutic benefits in animal models of Alzheimer's disease, particularly in ameliorating synaptic and cognitive deficits and slowing the progression of amyloid-beta and tau pathologies. This compound is utilized in the research of neurodegenerative diseases.

Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viruses, and is potentially therapeutic against COVID-19.

TREM2 agonist-2 (I-192) is an orally active and potent agonist of myeloid triggered receptor 2 (TREM2) for neurodegenerative disease research.

Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment.

TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells-2 (TREM2) agonist with an EC50 ranging from 3.0 μM to 100 μM.

Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.

Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.

Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.

Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).

Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.

Remogliflozin etabonate (GSK189075A) is a prodrug of regaliflozin and an inhibitor SGLT2 with Ki values of 1.95, 2.14, 8.57, and 43.1μM for hSGLT2, rSGLT2, rSGLT1, and hSGLT1, respectively.

Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-adrenoceptor.

(R)-Apremilast ((R)-CC-10004), the enantiomer of Apremilast, is one of the isoindoline derivatives.

Oxotremorine sesquifumarate is a muscarinic agonist.

(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-Dihydroxy-8-oxo-9-eremophilene-12-oic acid, a phytotoxin recently identified in Alternaria alternata ssp. tenuissima isolates, is linked to fruit spots on apples.

Gremubamab (MEDI3902), a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody, specifically targets and binds to the Pseudomonas aeruginosa PcrV protein and Psl exopolysaccharide. It shows promise for the study of Pseudomonas aeruginosa infections [1] [2].

4-Hydroxytoremifene is a selective estrogen receptor modulator toremifene active metabolite.

Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. cervinatalarvae weight gain and food consumption. 1.Gallagher, R.T., Latch, G.C., and Keogh, R.G.The janthitrems: Fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pasturesAppl. Environ. Microbiol.39(1)272-273(1980) 2.Babu, J.V., Popay, A.J., Miles, C.O., et al.Identification and structure elucidation of janthitrems A and D from Penicillium janthinellum and determination of the tremorgenic and anti-insect activity of janthitrems A and BJ. Agric. Food Chem.66(50)13116-13125(2018)

Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryeg

6β-Ethoxyfuranoeremophilane is a useful organic compound for research related to life sciences and the catalog number is T124153.

Janthitrem f, as a 10-0-acetyljanthitrem e or janthitrem e monoacetate, is a type ofnaphthopyran. Janthitrem F is prepared by Penicillium janthinellum. Tremorgenic mycotoxi.

Janthitrem B is a trematoxin produced by certain isolates of Penicillium violaceum.

Janthitrem E is a type of naphthopyran. Janthitrem E is obtained from Penicillium janthinellum. Tremorgenic mycotoxi.

6β-Ethoxy-8β,10β-dihydroxyeremophil-7(11)-en-12,8α-olide is a useful organic compound for research related to life sciences and the catalog number is T125285.

Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.

Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and ex

Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-α release by lipopolysaccharide (IC50: 104 nM).

Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.

Isoremoxipride hydrobromide is a dopamine antagonist.

Remdesivir de(ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human airway epithelial (HAE) cells, and 30 nM against murine hepatitis virus in delayed brain tumor cells. Notably effective in vitro against SARS-CoV-2 (COVID-19) infection, Remdesivir has garnered attention for its application in controlling the spread of the virus, as supported by references [1] [2].

Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68 with an EC50 of 170 nM, used in the study of autoimmune chronic inflammatory diseases [1].

Territrem A, a mycotoxin that induces tremors, is derived from the fungus Aspergillus terreus [1].

Enazadrem, a 5-lipoxygenase inhibitor, exhibits anti-inflammatory activities.

Remeisterol is a biochemical.

Remikiren is a highly specific renin inhibitor with oral activity for the treatment of hypertensio.

Remdesivir, also known as GS-5734, is a prodrug form of the antiviral nucleoside analog GS-44152. Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit SARS-CoV-2, in vitro and in vivo. Efficacy of remdesivir against Ebola virus has been demonstrated. Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary lesions in SARS-CoV-2-infecetd animals. Remdesivir has been used as a compassionate drug for treating COVID-19 patients. *******WARNING****** Our product remdesivir is a pure chemical solid powder which is only for laboratory research use, NOT FOR HUMAN OR PATIENT USE

Daigremontianin is a bufo dienolide similar to cardioside.

Fremanezumab (TEV-48125), a humanized IgG2a monoclonal antibody, potently and selectively targets the calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide implicated in the central and peripheral mechanisms of migraine. It holds promise for research into chronic migraine treatment [1].

Remtolumab (ABT-122), a dual-variable domain immunoglobulin, neutralizes tumor necrosis factor α (TNFα) and IL-17A, demonstrating dual inhibition of both. This compound is utilized in rheumatoid arthritis (RA) research [1] [2].

Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV.

Acremoxanthone C, a powerful calmodulin (CaM) inhibitor, originates from Purpureocillium lilacinum. It specifically interacts with the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, exhibiting a binding affinity characterized by a dissociation constant (Kd) of 18.25 nM.

Idremcinal is a motilin receptor agonist.

β-Aflatrem is a phenolic natural product. The catalog number is TN5609 and the CAS number is 144446-23-1. β-Aflatrem can be used as a reference standard.

6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane is a natural product from Ligularia songarica.

Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M phase, with the MIC value of 26.1 mic

Penitrem A is a selective antagonist of BK channel with antiproliferative and anti-invasive activities against multiple malignancies.

Siremadlin R Enantiomer is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific inhibitor of MDM-2/p53.

Janthitrem G is a type of naphthopyran. Janthitrem G is obtained from Penicillium janthinellum. Tremorgenic mycotoxi.