AhR

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix-period-aryl hydrocarbon receptor nuclear translocator-single-minded (bHLH-PAS) family of transcription factors, which act as biological sensors by initiating gene expression programs in response to endogenous and exogenous signals.

Cat. No.	Product name	CAS No.	Purity
T20625	Prochloraz	67747-09-5	98%
T20625	Prochloraz, a broad-spectrum contact imidazole fungicide, is used against several diseases in wheat, barley, and oleaginous plants but also for the treatment of ...
T5541	PDM11	1032508-03-4
T5541	PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)
T23151	Phortress	328087-38-3	100%
T23151	Phortress is a high affinity AhR ligand that elicits antitumor activity by inducing transcription of CYP1A1.
T4607	CAY 10465	688348-33-6	100%
T4607	CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
T4644	Tapinarof	79338-84-4	100%
T4644	Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
T10938	D-Kynurenine	13441-51-5	97.08%
T10938	D-Kynurenine is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D...
T5622	BAY-218	2162982-11-6	98%
T5622	AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
T7202	ITE	448906-42-1	98%
T7202	ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
T4928	L-Kynurenine	2922-83-0	98.44%
T4928	L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppress...
T1046	Mexiletine hydrochloride	5370-01-4	98.44%
T1046	Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. ...
TN1451	Brevifolincarboxylic acid	18490-95-4	99.42%
TN1451	Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarb...
T4608	PDM2	688348-25-6	99.57%
T4608	PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
T9822	WAY-605471	378223-81-5	99.57%
T9822	WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.
T2448	CH-223191	301326-22-7	99.58%
T2448	CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
T10007	1,4-Chrysenequinone	100900-16-1	99.65%
T10007	1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR).
T0343	Nimodipine	66085-59-4	99.71%
T0343	Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T5281	Skatole	83-34-1	99.74%
T5281	Skatole is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
T1960	YL-109	36341-25-0	99.77%
T1960	YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
T4938	Potassium 1H-indol-3-yl sulfate	2642-37-7	99.87%
T4938	Indoxyl sulfate (potassium salt) is an agonist for the human aryl hydrocarbon receptor (AHR). The aryl hydrocarbon receptor (AhR) has recently emerged as a patho...
T1159	Leflunomide	75706-12-6	99.9%
T1159	Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.