AhR

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix-period-aryl hydrocarbon receptor nuclear translocator-single-minded (bHLH-PAS) family of transcription factors, which act as biological sensors by initiating gene expression programs in response to endogenous and exogenous signals.

Cat. No.	Product name	CAS No.	Purity
T9112	(-)-Perillaldehyde	18031-40-8	98%
T9112	(-)-Perillaldehyde shows antibacterial activity.
T4928	L-Kynurenine	2922-83-0	98%
T4928	L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppress...
T1159	Leflunomide	75706-12-6	98%
T1159	Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
T4938	Potassium 1H-indol-3-yl sulfate	2642-37-7	98%
T4938	Potassium 1H-indol-3-yl sulfate is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pat...
T5281	Skatole	83-34-1	98%
T5281	Skatole is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
T1831	StemRegenin 1	1227633-49-9	98%
T1831	StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.
T9822	WAY-605471	378223-81-5	98%
T9822	WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.
T0343	Nimodipine	66085-59-4	98%
T0343	Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T2448	CH-223191	301326-22-7	98%
T2448	CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
T1046	Mexiletine hydrochloride	5370-01-4	98%
T1046	Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. ...
T1960	YL-109	36341-25-0	98%
T1960	YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
T5622	BAY-218	2162982-11-6	98%
T5622	AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
T7202	ITE	448906-42-1	98%
T7202	ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
T10938	D-Kynurenine	13441-51-5	98%
T10938	D-Kynurenine is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D...
T23151	Phortress	328087-38-3	98%
T23151	Phortress is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity.
T4607	CAY 10465	688348-33-6	98%
T4607	CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
T5541	PDM11	1032508-03-4	98%
T5541	PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)
T10007	1,4-Chrysenequinone	100900-16-1	98%
T10007	1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR).
TN1451	Brevifolincarboxylic acid	18490-95-4	98%
TN1451	Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarb...
T4644	Tapinarof	79338-84-4	98%
T4644	Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.