AhR|Targetmol

AhR

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix-period-aryl hydrocarbon receptor nuclear translocator-single-minded (bHLH-PAS) family of transcription factors, which act as biological sensors by initiating gene expression programs in response to endogenous and exogenous signals.

Cat No.	product name
T0343	Nimodipine	Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T1046	Mexiletine hydrochloride	Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine....
T1159	Leflunomide	Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
T1831	StemRegenin 1	StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.
T1960	YL-109	YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
T2448	CH 223191	CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
T4644	Benvitimod	Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
T4938	Indoxyl sulfate potassium salt	Indoxyl sulfate (potassium salt) is an agonist for the human aryl hydrocarbon receptor (AHR). The aryl hydrocarbon receptor (AhR) has recently emerged as a path...
T4928	L-Kynurenine	L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppres...
T5622	AHR antagonist 1	AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
T7202	ITE	ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
T5541	PDM 11	PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)
T10007	1,4-Chrysenequinone	1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR).

Cat No.

product name

T0343

Nimodipine

Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.

T1046

Mexiletine hydrochloride

Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine....

T1159

Leflunomide

Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.

T1831

StemRegenin 1

StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.

T1960

YL-109

YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.

T2448

CH 223191

CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).

T4644

Benvitimod

Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.

T4938

Indoxyl sulfate potassium salt

Indoxyl sulfate (potassium salt) is an agonist for the human aryl hydrocarbon receptor (AHR). The aryl hydrocarbon receptor (AhR) has recently emerged as a path...

T4928

L-Kynurenine

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppres...

T5622

AHR antagonist 1

AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.

T7202

ITE

ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.

T5541

PDM 11

PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)

T10007

1,4-Chrysenequinone

1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR).