T11154L |
EG01377 2HCl
|
2749438-61-5
|
98%
|
|
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HC...
|
T10863 |
Complement C5-IN-1
|
2365402-67-9
|
98%
|
|
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
|
T7497 |
C3a (70-77)
|
63555-63-5
|
98%
|
|
C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
|
T13379 |
(Z)-Leukadherin-1
|
2055362-72-4
|
98%
|
|
(Z)-Leukadherin-1 is an allosteric agonist of CD11b.
|
T9695L |
POT-4 acetate
|
|
98%
|
|
POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.
|
TP2296L |
TLQP 21 acetate
|
|
98%
|
|
TLQP 21 acetate is a potent agonist of G-protein-coupled receptor complement-3a receptor 1 (C3aR1). The EC50 values are 10.3 μM for mouse and 68.8 μM for human...
|
TP1305L |
LEP(116-130)(mouse)TFA(258276-95-8 free base)
|
TP1305L
|
98%
|
|
LEP(116-130)(mouse) is a synthetic leptin peptide fragment.
|
TP2334 |
PMX 53 acetate(219639-75-5 free base)
|
852629-88-0
|
98%
|
|
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 va...
|
T8509 |
Danicopan
|
1903768-17-1
|
98%
|
|
Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Da...
|
T60161 |
CP-289
|
1349637-14-4
|
98%
|
|
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
|
T1076 |
Dexamethasone
|
50-02-2
|
98%
|
|
Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exosomes containing inflammatory microRNA-15...
|
T60151 |
CP-447697
|
1092847-21-6
|
98%
|
|
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
|
T12506L1 |
PMX 205 acetate(514814-49-4 free base)
|
T12506L1
|
98%
|
|
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
|
T9316 |
JR14a
|
2411440-41-8
|
98%
|
|
JR14a is a potent antagonist of human complement C3a receptor.
|
T12851 |
SB290157 trifluoroacetate
|
1140525-25-2
|
98%
|
|
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
|
T9189 |
Iptacopan hydrochloride
|
1646321-63-2
|
98%
|
|
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and...
|
T64388 |
3-Phenoxybenzaldehyde
|
39515-51-0
|
98%
|
|
3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.
|
T3638 |
Leukadherin-1
|
344897-95-6
|
98%
|
|
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot...
|
T0945 |
Cyclosporin A
|
59865-13-3
|
98%
|
|
Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib...
|
T38287 |
C3a Receptor Agonist
|
944997-60-8
|
98%
|
|
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from bein...
|