T11366 |
Garcinol
|
78824-30-3
|
98%
|
|
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-...
|
T9373 |
DCH36_06
|
593273-05-3
|
|
|
DCH36_06 as a bona fide is a potent p300/CBP inhibitor
|
T11563 |
Histone Acetyltransferase Inhibitor II
|
932749-62-7
|
100%
|
|
Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 µM).with anti-acetylase activity in...
|
T15216 |
EML 425
|
1675821-32-5
|
100%
|
|
EML 425 is a potent and selective inhibitor of CREB binding protein (CBP)/p300 (IC50s: 2.9 and 1.1 μM, respectively).
|
T4679 |
WM-1119
|
2055397-28-7
|
96.59%
|
|
WM-1119 is a highly potent, selective KAT6A/B inhibitor
|
T9102 |
WM-3835
|
2229025-70-9
|
97.47%
|
|
WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferati...
|
T1516 |
Curcumin
|
458-37-7
|
97.51%
|
|
Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin bl...
|
T28471 |
PU139
|
158093-65-3
|
97.61%
|
|
PU139 is a novel inhibitor of histone acetyltransferase (HAT).
|
T6133 |
Remodelin hydrobromide
|
1622921-15-6
|
98%
|
|
Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
|
T14073 |
A-485
|
1889279-16-6
|
98.32%
|
|
A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively).
|
T8658 |
NEO2734
|
2081072-29-7
|
98.56%
|
|
NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).
|
T3217 |
PF-CBP1 hydrochloride
|
2070014-93-4
|
99%
|
|
PF-CBP1 is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM r...
|
T6668 |
SGC-CBP30
|
1613695-14-9
|
99.03%
|
|
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
|
T6584 |
MG 149
|
1243583-85-8
|
99.1%
|
|
MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
|
T3969 |
I-CBP112
|
1640282-31-0
|
99.1%
|
|
I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.
|
T12345 |
CBP/p300-IN-3
|
2299226-01-8
|
99.14%
|
|
P300/CBP-IN-3 is an inhibitor of p300/CBP histone acetyltransferase.
|
T5468 |
YF-2
|
1311423-89-8
|
99.19%
|
|
YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM...
|
T2452 |
C646
|
328968-36-1
|
99.21%
|
|
C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).
|
T9167 |
PF-9363
|
2569009-58-9
|
99.25%
|
|
PF-9363 is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.
|
T3499 |
Remodelin
|
949912-58-7
|
99.39%
|
|
Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.
|