NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.

Cat. No.	Product name	CAS No.	Purity
T3701	MCC950	210826-40-7	98%
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
T9222	Emlenoflast	1995067-59-8	98%
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
T28178	NLRP3-IN-9	88039-46-7	98%
NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...
T15052	Dapansutrile	54863-37-5
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T13375	YQ128	2454246-18-3
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T4164	CY-09	1073612-91-5	100%
CY-09 is an NLRP3 inhibitor.
T7597	6-Biopterin	22150-76-1	95.95%
6-Biopterin is a natural product,is a NO synthase cofactor.
T5838	L-Canavanine sulfate	2219-31-0	98%
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T7682	Asymmetric dimethylarginine	30315-93-6	98%
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T2845	Imperatorin	482-44-0	98.07%
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T3230	NLRP3-IN-2	16673-34-0	98.98%
It is a NLRP3 Inflammasome Inhibitor I.
T38361	GSK717	1595278-21-9	99.01%
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T6887	MCC950 sodium	256373-96-3	99.12%
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
T6S1367	Procyanidin B2	29106-49-8	99.21%
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
T0122	Bergenin	477-90-7	99.43%
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
TN1273	7,4'-Dihydroxyflavone	2196-14-7	99.6%
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
TQ0165	Arglabin	84692-91-1	99.62%
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
T3587	NOD-IN-1	132819-92-2	99.67%
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
T4217	INF39	866028-26-4	99.78%
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
T9572	BMS986299	2242952-69-6	99.93%
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T3701

MCC950

210826-40-7

98%

CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...

T9222

Emlenoflast

1995067-59-8

98%

Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.

T28178

NLRP3-IN-9

88039-46-7

98%

NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-tri...

T15052

Dapansutrile

54863-37-5

Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.

T13375

YQ128

2454246-18-3

YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.

T4164

CY-09

1073612-91-5

100%

CY-09 is an NLRP3 inhibitor.

T7597

6-Biopterin

22150-76-1

95.95%

6-Biopterin is a natural product,is a NO synthase cofactor.

T5838

L-Canavanine sulfate

2219-31-0

98%

L-Canavanine sulfate is a selective inducible NO synthase inhibitor.

T7682

Asymmetric dimethylarginine

30315-93-6

98%

Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)

T2845

Imperatorin

482-44-0

98.07%

Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.

T3230

NLRP3-IN-2

16673-34-0

98.98%

It is a NLRP3 Inflammasome Inhibitor I.

T38361

GSK717

1595278-21-9

99.01%

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...

T6887

MCC950 sodium

256373-96-3

99.12%

MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.

T6S1367

Procyanidin B2

29106-49-8

99.21%

Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...

T0122

Bergenin

477-90-7

99.43%