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NOD

Nucleotide-binding oligomerization domain proteins (NODs) are modular cytoplasmic proteins implicated in the recognition of peptidoglycan-derived molecules.
Cat No. product name
TN7099 Antcin A antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
T15052 Dapansutrile Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
T3092 Nigericin sodium salt Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
T3587 NOD-IN-1 NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
T3230 NLRP3-IN-2 It is a NLRP3 Inflammasome Inhibitor I.
T6591 Nodinitib-1 Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
T7597 6-Biopterin 6-Biopterin is a natural product,is a NO synthase cofactor.
T2845 Imperatorin Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T0122 Bergenin Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
T5838 L-Canavanine sulfate L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.
TQ0165 Arglabin Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
T6887 MCC950 sodium MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
T13375 YQ128 YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T4217 INF39 INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
T38361 GSK717 GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
T6S1367 Procyanidin B2 Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
T7682 Asymmetric dimethylarginine Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
TN1273 7,4'-Dihydroxyflavone 4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
T9222 Emlenoflast Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
T4164 CY-09 CY-09 is an NLRP3 inhibitor.
T3701 MCC950 CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and cas...
T0109 Molsidomine Molsidomine is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO)...
T13378 Z-Asp-CH2-DCB Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.
antcin A
TN7099
antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and an...
Dapansutrile
T15052
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
Nigericin sodium salt
T3092
Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi func...
NOD-IN-1
T3587
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
NLRP3-IN-2
T3230
It is a NLRP3 Inflammasome Inhibitor I.
Nodinitib-1
T6591
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
6-Biopterin
T7597
6-Biopterin is a natural product,is a NO synthase cofactor.
Imperatorin
T2845
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Bergenin
T0122
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
L-Canavanine sulfate
T5838
L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.
Arglabin
TQ0165
Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
MCC950 sodium
T6887
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
YQ128
T13375
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
INF39
T4217
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.
GSK717
T38361
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signali...
Procyanidin B2
T6S1367
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inf...
Asymmetric dimethylarginine
T7682
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
7,4'-Dihydroxyflavone
TN1273
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
Emlenoflast
T9222
Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
CY-09
T4164
CY-09 is an NLRP3 inhibitor.
MCC950
T3701
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and ca...
Molsidomine
T0109
Molsidomine is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO)...
Z-Asp-CH2-DCB
T13378
Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.