Molsidomine is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO...
Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action. |
Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase. |
Dapansutrile is an orally active inhibitor of NLRP3 inflammasome. It has anti-inflammatory and analgesic activity. |
Imperatorin is a modulator of p38,ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo. |
||NLRP3 Inflammasome Inhibitor I
It is a NLRP3 Inflammasome Inhibitor I. |
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors. |
CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and c...
CY-09 is an NLRP3 inhibitor. |
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor. |
L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. |
Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM. |
MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor. |
Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 in...
6-Biopterin is a natural product,is a NO synthase cofactor. |
4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |