Search Result

Search Results for " mek "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T28012	MEK-IN-4		MEK
	MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.		MEK
T11993	MEK inhibitor		MEK
	MEK inhibitor is a potent MEK inhibitor with antitumor potency.		MEK
T6843	GDC-0623	G-868,GDC0623,RG 7421,MEK inhibitor 1	Apoptosis , MEK
	GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.		Apoptosis , MEK
T10675	MEK-IN-1		MEK
	MEK-IN-1 is a MEK inhibitor.		MEK
T73364	MEK-IN-5
	MEK-IN-5, a potent MEK inhibitor and nitric oxide (NO) donor, effectively decreases pMEK and pERK levels in a dose-dependent and time-dependent fashion. Additionally, it induces apoptosis in MDA-MB-231 cells.
T79047	MEK-IN-6		ERK
	MEK-IN-6 (Example 69), a potent MEK inhibitor, effectively inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells, with an IC50 of 2 nM, making it valuable for cancer research [1].		ERK
T79048	MEK-IN-6 hydrate		MEK
	MEK-IN-6 hydrate (compound 69), a MEK inhibitor, exhibits an IC50 value of 2 nM in A375 cells [1].		MEK
T74361	MEK/PI3K-IN-2
	MEK/PI3K-IN-2 (compound 6s), a potent inhibitor of both MEK and PI3K, demonstrates IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ). This compound effectively reduces pAKT and pERK1/2 levels, exhibiting a...
T74360	MEK/PI3K-IN-1
	MEK/PI3K-IN-1 (compound 6r) is a potent inhibitor targeting both MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces levels of pAKT and pERK1/2, demonst...
T2508	Binimetinib	ARRY-438162,ARRY-162,MEK162	MEK , Autophagy
	Binimetinib (ARRY-162) (MEK162, ARRY-162, ARRY-438162) is an orally available inhibitor of MEK1/2 (IC50: 12 nM) in a cell-free assay.		MEK , Autophagy
T6152	PD318088		MEK
	PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.		MEK
T6692	TAK-733	TAK733,TAK 733	MEK
	TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.		MEK
T2708	SL327	SL 327,SL-327	MEK , DNA/RNA Synthesis
	SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.		MEK , DNA/RNA Synthesis
T6785	BI-847325		Apoptosis , MEK , Aurora Kinase
	BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.		Apoptosis , MEK , Aurora Kinase
T21635	PD184161		MEK
	PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].		MEK
T2443	CI-1040	PD 184352	Apoptosis , MEK
	CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).		Apoptosis , MEK
T21295	BIX02189	BIX 02189	ERK , MEK
	BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).		ERK , MEK
T2623	PD98059	PD 98059	ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
	PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhibits autophagy.		ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
T7610	GW284543	UNC10225170	MEK
	GW284543 (UNC10225170) is a selective inhibitor of MEK5 .		MEK
T21980	PD 198306		MEK
	PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.		MEK
T5412	RO4987655	CH4987655,RG7167	MEK
	RO4987655 (RG7167) is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).		MEK
T6189	Mirdametinib	PD325901,PD0325901	Apoptosis , MEK , Autophagy
	Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis.		Apoptosis , MEK , Autophagy
T6971	Ro 5126766	CH5126766,Avutometinib,VS-6766,RO5126766	Raf , MEK
	RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.		Raf , MEK
T1144L	Lidocaine Hydrochloride hydrate		EGFR , Sodium Channel
	Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.		EGFR , Sodium Channel
T6218	Selumetinib	ARRY-142886,AZD6244	Apoptosis , ERK , MEK
	Selumetinib (AZD6244) (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).		Apoptosis , ERK , MEK
T6760	APS-2-79 hydrochloride	APS-2-79 HCl,APS-2-79	MEK , MAPK
	APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activ...		MEK , MAPK
T0468	Lidocaine	Lignocaine,Alphacaine,Xylocaine	Apoptosis , ERK , NF-κB , MEK , Sodium Channel , Histamine Receptor
	Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammat...
T6083	AZD8330	ARRY-424704,ARRY-704	ERK , MEK
	AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.		ERK , MEK
T2125	Trametinib	GSK1120212,JTP-74057	Apoptosis , MEK , Autophagy
	Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.		Apoptosis , MEK , Autophagy
T6223	U0126-EtOH	U0126 Ethanol,U0126	Mitophagy , Influenza Virus , MEK , Autophagy
	U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).		Mitophagy , Influenza Virus , MEK , Autophagy
T2378	RGB-286638 free base		GSK-3 , MEK , JAK , CDK
	RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 a...		GSK-3 , MEK , JAK , CDK
T3623	Cobimetinib	RG7420,XL518,GDC-0973	Apoptosis , MEK
	Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e...		Apoptosis , MEK
T6636	Refametinib	BAY 86-97661,BAY 869766,RDEA119	MEK
	Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).		MEK
T1144	Lidocaine hydrochloride	Lidocaine HCL,Lignocaine hydrochloride,Xyloneural,Lidothesin	Apoptosis , ERK , NF-κB , MEK , Sodium Channel
	Lidocaine hydrochloride (Lignocaine hydrochloride) is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its ...		Apoptosis , ERK , NF-κB , MEK , Sodium Channel
T6131	Pimasertib	AS703026,MSC1936369B,SAR 245509	MEK
	Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.		MEK
T40206	MEK4 inhibitor-1	MEK4 inhibitor-1
	MEK4 inhibitor-1 is a newly developed compound specifically designed to inhibit the activity of MEK4, a key enzyme involved in pancreatic adenocarcinoma, with an IC 50 value of 61 nM.
T20168	Aurothiomalate sodium	Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others , PKC
	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...		Others , PKC
T5857	Trametinib (DMSO solvate)	Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)	Apoptosis , MEK
	Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)		Apoptosis , MEK
T9321	Zapnometinib	ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid	Influenza Virus , MEK , Antibacterial
	Zapnometinib (ATR-002) is a MEK inhibitor.		Influenza Virus , MEK , Antibacterial
T21332	U0126	U 0126,U-0126	Mitophagy , MEK , Autophagy
	U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively. U0126 inhibits autophagy and mitophagy.		Mitophagy , MEK , Autophagy
T22677	Cobimetinib racemate	Cobimetinib (racemate)	MEK
	Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated protein kinase, is a key component of the RAS/RAF/MEK/ERK pathwa...		MEK
T76777	Bermekimab	MABp1	IL Receptor
	Bermekimab (MABp1) is a humanized monoclonal antibody against interleukin-1α (IL-1α).Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.		IL Receptor
T63547	MEK1/2-IN-2
	MEK1/2-IN-2 is a potent, ATP-competitive MEK1/2 inhibitor that exhibits equal inhibitory effects on wild-type MEK1/2 and a group of MEK1/2 mutant cells.
T72407	C-Met/MEK1/Flt-3-IN-1
	Antiproliferative Against-3 (comp 33) demonstrates significant activity against Hela (IC 50 = 0.21 µM), A549 (IC 50 = 0.39 µM), and MCF-7 (IC 50 = 0.33 µM) cell lines. Additionally, it induces apoptosis in a dose-depende...
T76556	MEK1 Derived Peptide Inhibitor 1
	MEK1 Derived Peptide Inhibitor 1, a peptide inhibitor, prevents the in vitro activation of ERK2 by MEK1, exhibiting an inhibitory concentration (IC 50) of 30 μM. It is utilized in the study of cell-permeable [1].
T79144	PROTAC MEK1 Degrader-1		PROTACs
	PROTAC MEK1 Degrader-1, a targeted protein degradation agent, combines a MEK1 inhibitor with a von Hippel-Lindau ligand to effectively inhibit ERK1/2 phosphorylation. With a pIC50 value of 7.0, it exhibits antiproliferat...		PROTACs
T76557	Myristoyl-MEK1 Derived Peptide Inhibitor 1
	Myristoyl-MEK1 Derived Peptide Inhibitor 1, the myristoylated variant of MEK1 Derived Peptide Inhibitor 1, effectively inhibits ERK activation, demonstrating an inhibitory concentration (IC50) of 10 μM [1].
T62079	MEK4 inhibitor-2
	MEK4 Inhibitor-2, a novel MEK4 inhibitor, demonstrates efficacy against pancreatic adenocarcinoma, exhibiting an IC50 value of 83 nM.
T76798	Bimekizumab
	Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody), a humanized monoclonal antibody, selectively neutralizes IL-17A and IL-17F, both of which promote osteogenic differentiation in human periosteum-derived cells (...
T80543	STE-MEK1(13)	ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂	ERK
	STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes the phosphorylation of ERK1/2, as demonstrated in studies [1] [2].		ERK

Compounds

Synonym: G-868,GDC0623,RG 7421,MEK inhibitor 1

Target: Apoptosis, MEK

Synonym: ARRY-438162,ARRY-162,MEK162

Target: MEK, Autophagy

Synonym: TAK733,TAK 733

Target: MEK

SL327

T2708

Synonym: SL 327,SL-327

Target: MEK, DNA/RNA Synthesis

BI-847325

T6785

Synonym:

Target: Apoptosis, MEK, Aurora Kinase

Target: Apoptosis, MEK

Target: ERK, Aryl Hydrocarbon Receptor, MEK, Autophagy

Synonym: CH4987655,RG7167

Target: MEK

Mirdametinib

T6189

Synonym: PD325901,PD0325901

Target: Apoptosis, MEK, Autophagy

Ro 5126766

T6971

Synonym: CH5126766,Avutometinib,VS-6766,RO5126766

Target: Raf, MEK

Lidocaine Hydrochloride hydrate

T1144L

Synonym:

Target: EGFR, Sodium Channel

Selumetinib

T6218

Synonym: ARRY-142886,AZD6244

Target: Apoptosis, ERK, MEK

APS-2-79 hydrochloride

T6760

Synonym: APS-2-79 HCl,APS-2-79

Target: MEK, MAPK

Lidocaine

T0468

Synonym: Lignocaine,Alphacaine,Xylocaine

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel, Histamine Receptor

AZD8330

T6083

Synonym: ARRY-424704,ARRY-704

Target: ERK, MEK

Trametinib

T2125

Synonym: GSK1120212,JTP-74057

Target: Apoptosis, MEK, Autophagy

U0126-EtOH

T6223

Synonym: U0126 Ethanol,U0126

Target: Mitophagy, Influenza Virus, MEK, Autophagy

RGB-286638 free base

T2378

Synonym:

Target: GSK-3, MEK, JAK, CDK

Cobimetinib

T3623

Synonym: RG7420,XL518,GDC-0973

Target: Apoptosis, MEK

Refametinib

T6636

Synonym: BAY 86-97661,BAY 869766,RDEA119

Target: MEK

Lidocaine hydrochloride

T1144

Synonym: Lidocaine HCL,Lignocaine hydrochloride,Xyloneural,Lidothesin

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel

Pimasertib

T6131

Synonym: AS703026,MSC1936369B,SAR 245509

Target: MEK

MEK4 inhibitor-1

T40206

Synonym: MEK4 inhibitor-1

Target:

Aurothiomalate sodium

T20168

Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate

Target: Others, PKC

Trametinib (DMSO solvate)

T5857

Synonym: Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)

Target: Apoptosis, MEK

zapnometinib

T9321

Synonym: ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid

Target: Influenza Virus, MEK, Antibacterial

U0126

T21332

Synonym: U 0126,U-0126

Target: Mitophagy, MEK, Autophagy

Cobimetinib racemate

T22677

Synonym: Cobimetinib (racemate)

c-Met/MEK1/Flt-3-IN-1

T72407

Synonym:

Target:

MEK1 Derived Peptide Inhibitor 1

T76556

Synonym:

Target:

PROTAC MEK1 Degrader-1

T79144

Synonym:

Target: PROTACs

Myristoyl-MEK1 Derived Peptide Inhibitor 1

Synonym: ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂

Target: ERK

Cat No.	Product Name	Synonyms	Targets
TMS2181	Trans-Zeatin	(E)-Zeatin	ERK , MEK , Endogenous Metabolite
	trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.		ERK , MEK , Endogenous Metabolite
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
T2836	Isorhamnetin	3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin	MEK , PI3K , Endogenous Metabolite
	Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...		MEK , PI3K , Endogenous Metabolite
T6S1740	Nardosinone		Others
	1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...		Others
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T17261	Xantocillin		Others
	Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.		Others
TN1953	Morusinol		ERK , MEK , Autophagy , Ras
	Morusinol is a flavonoid extracted from the root bark of Morus alba. Morusinol has antiplatelet and anticancer activities, inhibits arterial thrombosis in vivo, and exerts antitumor activity by inducing autophagy, G2/M c...		ERK , MEK , Autophagy , Ras

Natural Products

trans-Zeatin

TMS2181

Synonym: (E)-Zeatin

Target: ERK, MEK, Endogenous Metabolite

anemarsaponin B

T7030

Synonym:

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Isorhamnetin

T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

Target: Apoptosis, Akt, JNK, Autophagy

Target: ERK, MEK, Autophagy, Ras

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00812	Midkine Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPK-00024	Midkine Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPK-00023	Midkine Protein, Human, Recombinant (His & Avi)	Human	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPJ-01378	Mp1 Protein, Human, Recombinant (His)	Human	E. coli
	Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding pro...
TMPY-04365	MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04748	MKK6 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04544	MEK2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/...
TMPY-04749	MKK6 Protein, Human, Recombinant (S207D, T211D)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04364	MKK6 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04569	MEK1 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	MEK1, also known as MAP2K1 and MKK1, is a member of the dual-specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kin...
TMPY-04756	MEK1 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	MEK1, also known as MAP2K1 and MKK1, is a member of the dual-specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kin...
TMPY-03564	TSPAN8 Protein, Human, Recombinant (His)	Human	HEK293
	Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-04410	MAP4K5 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and MAP4K5, is a cytoplasm protein that belongs to the protein ...
TMPY-04374	MST4 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains ...
TMPY-04412	Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein,...
TMPY-03675	TSPAN8 Protein, Human, Recombinant (mFc)	Human	HEK293
	Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPY-02519	BLVRB Protein, Human, Recombinant (His)	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann...
TMPY-04389	MAP3K8 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that ...
TMPY-04562	GRK2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, inte...
TMPH-00297	S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)	Bovine	E. coli
	S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal act...

Midkine Protein, Mouse, Recombinant (His)

TMPK-00812

Species: Mouse

Expression System: E. coli

Midkine Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00024

Species: Human

Expression System: E. coli

Midkine Protein, Human, Recombinant (His & Avi)

TMPK-00023

Species: Human

Expression System: E. coli

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus-Insect Cells

Mp1 Protein, Human, Recombinant (His)

TMPJ-01378

Species: Human

Expression System: E. coli

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)

TMPY-04365

Species: Human

Expression System: Baculovirus-Insect Cells

MKK6 Protein, Human, Recombinant

TMPY-04748

Species: Human

Expression System: Baculovirus-Insect Cells

MEK2 Protein, Human, Recombinant (GST)

TMPY-04544

Species: Human

Expression System: Baculovirus-Insect Cells

MKK6 Protein, Human, Recombinant (S207D, T211D)

TMPY-04749

Species: Human

Expression System: Baculovirus-Insect Cells

MKK6 Protein, Human, Recombinant (His & GST)

TMPY-04364

Species: Human

Expression System: Baculovirus-Insect Cells

MEK1 Protein, Mouse, Recombinant (His & GST)

TMPY-04569

Species: Mouse

Expression System: Baculovirus-Insect Cells

MEK1 Protein, Mouse, Recombinant

TMPY-04756

Species: Mouse

Expression System: Baculovirus-Insect Cells

TSPAN8 Protein, Human, Recombinant (His)

TMPY-03564

Species: Human

Expression System: HEK293

FGF-4 Protein, Human, Recombinant

TMPY-05004

Species: Human

Expression System: E. coli

MAP4K5 Protein, Human, Recombinant (His & GST)

TMPY-04410

Species: Human

Expression System: Baculovirus-Insect Cells

MST4 Protein, Human, Recombinant (GST)

TMPY-04374

Species: Human

Expression System: Baculovirus-Insect Cells

Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)

TMPY-04412

Species: Human

Expression System: Baculovirus-Insect Cells

TSPAN8 Protein, Human, Recombinant (mFc)

TMPY-03675

Species: Human

Expression System: HEK293

BLVRB Protein, Human, Recombinant (His)

TMPY-02519

Species: Human

Expression System: E. coli

MAP3K8 Protein, Human, Recombinant (GST)

TMPY-04389

Species: Human

Expression System: Baculovirus-Insect Cells

GRK2 Protein, Human, Recombinant (His & GST)

TMPY-04562

Species: Human

Expression System: Baculovirus-Insect Cells

S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)

TMPH-00297

Species: Bovine

Expression System: E. coli

Cat No.	Product Name
L2192	Anti-Pancreatic Cancer Compound Library	2267 compounds
	A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS;
L1610	FDA-Approved Kinase Inhibitor Library	266 compounds
	A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600	Kinase Inhibitor Library	2720 compounds
	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;

Libraries

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2267

FDA-Approved Kinase Inhibitor Library

L1610

Compounds: 266

Kinase Inhibitor Library

L1600

Compounds: 2720